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All Outputs (3)

Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage (2021)
Journal Article
Zhu, Q., Sang, F., Withey, S., Tang, W., Dietmann, S., Klisch, D., …Alberio, R. (2021). Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage. Cell Reports, 34(6), Article 108735. https://doi.org/10.1016/j.celrep.2021.108735

Investigations of the human germline and programming are challenging because of limited access to embryonic material. However, the pig as a model may provide insights into transcriptional network and epigenetic reprogramming applicable to both specie... Read More about Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage.

Untangling early embryo development using single cell genomics (2020)
Journal Article
Alberio, R. (2020). Untangling early embryo development using single cell genomics. Theriogenology, 150, 55-58. https://doi.org/10.1016/j.theriogenology.2020.01.062

The zygote undergoes five cell divisions prior to the first signs of lineage segregation. Blastocyst formation requires segregation of the trophectoderm, needed for implantation, and the inner cell mass, which differentiate towards the major lineages... Read More about Untangling early embryo development using single cell genomics.

Exogenous human OKSM factors maintain pluripotency gene expression of bovine and porcine iPS-like cells obtained with STEMCCA delivery system (2018)
Journal Article
Canizo, J. R., Vazquez Echegaray, C., Klisch, D., Aller, J. F., Paz, D. A., Alberio, R. H., …Guberman, A. S. (2018). Exogenous human OKSM factors maintain pluripotency gene expression of bovine and porcine iPS-like cells obtained with STEMCCA delivery system. BMC Research Notes, 11, Article 509. https://doi.org/10.1186/s13104-018-3627-8

Objectives The use of induced pluripotent stem (iPS) cells as an alternative to embryonic stem cells to produce transgenic animals requires the development of a biotechnological platform for their generation. In this study, different strategies fo... Read More about Exogenous human OKSM factors maintain pluripotency gene expression of bovine and porcine iPS-like cells obtained with STEMCCA delivery system.