TNF and IFN Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein
(2010)
Journal Article
Clarke, D. L., Clifford, R. L., Jindarat, S., Proud, D., Pang, L., Belvisi, M., & Knox, A. J. (2010). TNF and IFN Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein. Journal of Biological Chemistry, 285(38), 29101-29110. https://doi.org/10.1074/jbc.m109.0999952
Asthmatic airway smooth muscle (ASM) expresses interferon-?-inducible protein-10 (CXCL10), a chemokine known to mediate mast cell migration into ASM bundles that has been reported in the airways of asthmatic patients. CXCL10 is elevated in patients s... Read More about TNF and IFN Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein.