Research Repository

See what's under the surface


Bacteriophage ZCKP1: a potential treatment for Klebsiella pneumoniae isolated from diabetic foot patients (2018)
Journal Article
Taha, O. A., Connerton, P., Connerton, I., & El-Shibiny, A. (2018). Bacteriophage ZCKP1: a potential treatment for Klebsiella pneumoniae isolated from diabetic foot patients. Frontiers in Microbiology, 9, doi:10.3389/fmicb.2018.02127

The recorded growth in infection by multidrug resistant bacteria necessitates prompt efforts towards developing alternatives to antibiotics, such as bacteriophage therapy. Immuno-compromised patients with diabetes mellitus are particularly prone to f... Read More

Campylobacters and their bacteriophages from chicken liver: the prospect for phage biocontrol (2016)
Journal Article
Firlieyanti, A. S., Connerton, P. L., & Connerton, I. F. (2016). Campylobacters and their bacteriophages from chicken liver: the prospect for phage biocontrol. International Journal of Food Microbiology, 237, doi:10.1016/j.ijfoodmicro.2016.08.026. ISSN 0168-1605

Consumption of foods containing chicken liver has been associated with Campylobacter enteritis. Campylobacters can contaminate the surface of livers post-mortem but can also arise through systemic infection of colonising bacteria in live birds. The u... Read More

Filamentation of Campylobacter in broth cultures (2015)
Journal Article
Ghaffar, N. M., Connerton, P. L., & Connerton, I. F. (2015). Filamentation of Campylobacter in broth cultures. Frontiers in Microbiology, 6(657), doi:10.3389/fmicb.2015.00657. ISSN 1664-302X

The transition from rod to filamentous cell morphology has been identified as a response to stressful conditions in many bacterial species and has been ascribed to confer certain survival advantages. Filamentation of Campylobacter jejuni was demonstr... Read More

Host adaption to the bacteriophage carrier state of Campylobacter jejuni (2015)
Journal Article
Brathwaite, K. J., Siringan, P., Connerton, P. L., & Connerton, I. F. (2015). Host adaption to the bacteriophage carrier state of Campylobacter jejuni. Research in Microbiology, doi:10.1016/j.resmic.2015.05.003. ISSN 0923-2508

The carrier state of the foodborne pathogen Campylobacter jejuni represents an alternative life cycle whereby virulent bacteriophage can persistent in association with host bacteria without commitment to lysogeny. Host bacteria exhibit significant ph... Read More

Alternative bacteriophage life cycles: the carrier state of Campylobacter jejuni (2014)
Journal Article
Siringan, P., Connerton, P. L., Cummmings, N. J., & Connerton, I. F. (2014). Alternative bacteriophage life cycles: the carrier state of Campylobacter jejuni. Open Biology, 4(3), doi:10.1098/rsob.130200. ISSN 2046-2441

Members of the genus Campylobacter are frequently responsible for human enteric disease, often through consumption of contaminated poultry products. Bacteriophages are viruses that have the potential to control pathogenic bacteria, but understanding... Read More

Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens (2005)
Journal Article
Loc Carrillo, C., Atterbury, R. J., El-Shibiny, A., Connerton, P. L., Dillon, E., Scott, A., & Connerton, I. F. (2005). Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens. Applied and Environmental Microbiology, 71(11), doi:10.1128/AEM.71.11.6554-6563.2005. ISSN 0099-2240

Colonization of broiler chickens by the enteric pathogen Campylobacter jejuni is widespread and difficult to prevent. Bacteriophage therapy is one possible means by which this colonization could be controlled, thus limiting the entry of campylobacter... Read More

Correlation of Campylobacter bacteriophage with reduced presence of hosts in broiler chicken ceca (2005)
Journal Article
Atterbury, R. J., Dillon, E., Swift, C., Connerton, P. L., Frost, J., Dodd, C. E., …Connerton, I. F. (2005). Correlation of Campylobacter bacteriophage with reduced presence of hosts in broiler chicken ceca. Applied and Environmental Microbiology, 71(8), doi:10.1128/AEM.71.8.4885-4887.2005. ISSN 0099-2240

Campylobacter jejuni and Campylobacter-specific bacteriophage were enumerated from broiler chicken ceca selected from 90 United Kingdom flocks (n = 205). C. jejuni counts in the presence of bacteriophage (mean log10 5.1 CFU/g) were associated with a... Read More

Isolation and characterization of Campylobacter bacteriophages from retail poultry (2003)
Journal Article
Atterbury, R. J., Connerton, P. L., Dodd, C. E., Rees, C. E., & Connerton, I. F. (2003). Isolation and characterization of Campylobacter bacteriophages from retail poultry. Applied and Environmental Microbiology, 69(8), doi:10.1128/AEM.69.8.4511-4518.2003. ISSN 0099-2240

The ability of phages to survive processing is an important aspect of their potential use in the biocontrol of Campylobacter in poultry production. To this end, we have developed a procedure to recover Campylobacter bacteriophages from chilled and fr... Read More