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All Outputs (5)

A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status (2015)
Journal Article
Crossland, H., Sood, S., PHILLIPS, B., Gallagher, I. J., ATHERTON, P., Lunnon, K., …Timmons, A. H. A. J. A. (2015). A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status. Genome Biology, 16(1), 1-17. https://doi.org/10.1186/s13059-015-0750-x

Background Diagnostics of the human ageing process may help predict future healthcare needs or guide preventative measures for tackling diseases of older age. We take a transcriptomics approach to build the first reproducible multi-tissue RNA expres... Read More about A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status.

Internal comparison between deuterium oxide (D2O) and L-[ring-13C6] phenylalanine for acute measurement of muscle protein synthesis in humans (2015)
Journal Article
Smith, K., Cegielski, J., Wilkinson, D., Phillips, B., Boereboom, C., Lund, J., & Atherton, P. (2015). Internal comparison between deuterium oxide (D2O) and L-[ring-13C6] phenylalanine for acute measurement of muscle protein synthesis in humans. Physiological Reports, 3(7), https://doi.org/10.14814/phy2.12433

Stable isotope tracer methodologies are becoming increasingly widespread in metabolic research; yet a number of factors restrict their implementation, such as, i.v infusions, multiple cannulae, tissue samples, and significant cost. We recently valida... Read More about Internal comparison between deuterium oxide (D2O) and L-[ring-13C6] phenylalanine for acute measurement of muscle protein synthesis in humans.

Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise (2015)
Journal Article
Bukhari, S. S., Phillips, B. E., Wilkinson, D. J., Limb, M. C., Rankin, D., Mitchell, W. K., …Atherton, P. J. (2015). Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise. AJP - Endocrinology and Metabolism, 308(12), E1056-E1065. https://doi.org/10.1152/ajpendo.00481.2014

© 2015 American Physiological Society. All Rights Reseved. Dysregulated anabolic responses to nutrition/exercise may contribute to sarcopenia; however, these characteristics are poorly defined in female populations. We determined the effects of two f... Read More about Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise.

Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling (2015)
Journal Article
Brook, M. S., Wilkinson, D. J., Mitchell, W. K., Lund, J. N., Szewczyk, N. J., Greenhaff, P. L., …Atherton, P. (2015). Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling. FASEB Journal, 29(11), https://doi.org/10.1096/fj.15-273755