Skip to main content

Research Repository

Advanced Search

All Outputs (4)

In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B (2015)
Journal Article
Qazzaz, M. E., Raja, V. J., Lim, K., Kam, T., Lee, J. B., Gershkovich, P., & Bradshaw, T. D. (2016). In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B. Cancer Letters, 370(2), https://doi.org/10.1016/j.canlet.2015.10.013

Natural products play a pivotal role in medicine especially in the cancer arena. Many drugs that are currently used in cancer chemotherapy originated from or were inspired by nature. Jerantinine B (JB) is one of seven novel Aspidosperma indole alkalo... Read More about In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B.

Development of a simple and sensitive HPLC-UV method for the simultaneous determination of cannabidiol and ?(9)-tetrahydrocannabinol in rat plasma (2015)
Journal Article
Zgair, A., Wong, J., Sabri, A., Fischer, P., Barrett, D., Constantinescu, C., & Gershkovich, P. (2015). Development of a simple and sensitive HPLC-UV method for the simultaneous determination of cannabidiol and ?(9)-tetrahydrocannabinol in rat plasma. Journal of Pharmaceutical and Biomedical Analysis, 114, 145-151. doi:10.1016/j.jpba.2015.05.019

Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis (2015)
Journal Article
Benito-Gallo, P., Franceschetto, A., Wong, J. C., Marlow, M., Zann, V., Scholes, P., & Gershkovich, P. (2015). Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis. European Journal of Pharmaceutics and Biopharmaceutics, 93, https://doi.org/10.1016/j.ejpb.2015.04.027

Triglycerides (TG) are one of the most common excipients used in oral lipid-based formulations. The chain length of the TG plays an important role in the oral bioavailability of the co-administered drug. Fatty acid (FA) chain-length specificity of po... Read More about Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis.

Characterisation of human saliva as a platform for oral dissolution medium development (2015)
Journal Article
Gittings, S., Turnbull, N., Henry, B., Roberts, C. J., & Gershkovich, P. (2015). Characterisation of human saliva as a platform for oral dissolution medium development. European Journal of Pharmaceutics and Biopharmaceutics, 91, 16-24. https://doi.org/10.1016/j.ejpb.2015.01.007

Human saliva is a biological fluid of great importance in the field of dissolution testing. However, until now, no consensus has been reached on its key characteristics relevant to dissolution testing. As a result, it is difficult to select or develo... Read More about Characterisation of human saliva as a platform for oral dissolution medium development.