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Culturing and Mating of Aspergillus fumigatus (2019)
Journal Article
Ashton, G. D., & Dyer, P. S. (2019). Culturing and Mating of Aspergillus fumigatus. Current Protocols in Microbiology, 54(1), doi:10.1002/cpmc.87

Aspergillus fumigatus is an opportunistic human fungal pathogen, capable of causing invasive aspergillosis in patients with compromised immune systems. The fungus was long considered a purely asexual organism. However, a sexual cycle was reported in... Read More about Culturing and Mating of Aspergillus fumigatus.

Whole-genome sequence data uncover widespread heterothallism in the largest group of lichen-forming fungi (2019)
Journal Article
Pizarro, D., Dal Grande, F., Don Leavitt, S., Stanley Dyer, P., Schmitt, I., Crespo, A., …Kumar Divakar, P. (2019). Whole-genome sequence data uncover widespread heterothallism in the largest group of lichen-forming fungi. Genome Biology and Evolution, 11(3), 721-730. doi:10.1093/gbe/evz027

Fungal reproduction is regulated by the mating-type (MAT1) locus, which typically comprises two idiomorphic genes. The presence of one or both allelic variants at the locus determines the reproductive strategy in Fungi – homothallism vs. heterothalli... Read More about Whole-genome sequence data uncover widespread heterothallism in the largest group of lichen-forming fungi.

Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus (2017)
Journal Article
Vries, R. P. D., Riley, R., Wiebenga, A., Aguilar-Osorio, G., Amillis, S., Akemi Uchima, C., …Grigoriev, I. V. (2017). Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus. Genome Biology, 18, doi:10.1186/s13059-017-1151-0. ISSN 1474-760X

Background: The fungal genus Aspergillus is of critical importance to humankind. Species include those with industrial applications, important pathogens of humans, animals and crops, a source of potent carcinogenic contaminants of food, and an import... Read More about Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.

Phenotypic heterogeneity in fungi: Importance and methodology (2016)
Journal Article
Hewitt, S. K., Foster, D. S., Dyer, P. S., & Avery, S. V. (2016). Phenotypic heterogeneity in fungi: Importance and methodology. Fungal Biology Reviews, 30(4), 176-184. https://doi.org/10.1016/j.fbr.2016.09.002

Phenotypic heterogeneity describes the variation that exists between individual cells, spores or other biological entities within genetically-uniform populations of fungi or other organisms. Studies over the last 10–-15 years have successfully used l... Read More about Phenotypic heterogeneity in fungi: Importance and methodology.

Sexual reproduction of human fungal pathogens (2014)
Journal Article
Heitman, J., Carter, D. A., Dyer, P. S., & Soll, D. R. (in press). Sexual reproduction of human fungal pathogens. Cold Spring Harbor perspectives in medicine, 4(8), doi:10.1101/cshperspect.a019281

We review here recent advances in our understanding of sexual reproduction in fungal pathogens that commonly infect humans, including Candida albicans, Cryptococcus neoformans/gattii, and Aspergillus fumigatus. Where appropriate or relevant, we intro... Read More about Sexual reproduction of human fungal pathogens.

Differences in MAT gene distribution and expression between Rhynchosporium species on grasses (2014)
Journal Article
King, K., West, J., Fitt, B., & Dyer, P. S. (2015). Differences in MAT gene distribution and expression between Rhynchosporium species on grasses. Plant Pathology, 64(2), doi:10.1111/ppa.12265

Leaf blotch is a globally important disease of barley crops and other grasses that is caused by at least five host-specialized species in the fungal genus Rhynchosporium. The pathogen R. commune (specialized to barley, brome-grass and Italian ryegras... Read More about Differences in MAT gene distribution and expression between Rhynchosporium species on grasses.

Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress (2013)
Journal Article
Holland, S. L., Reader, T., Dyer, P. S., & Avery, S. V. (2013). Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress. Environmental Microbiology, doi:10.1111/1462-2920.12243

Populations of genetically uniform microorganisms exhibit phenotypic heterogeneity, where individual cells have varying phenotypes. Such phenotypes include fitness-determining traits. Phenotypic heterogeneity has been linked to increased populati... Read More about Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress.

Sexual reproduction and mating-type-mediated strain development in the penicillin-producing fungus Penicillium chrysogenum (2013)
Journal Article
Böhm, J., Hoff, B., O'Gorman, C. M., Wolfers, S., Klix, V., Binger, D., …Kück, U. (2013). Sexual reproduction and mating-type-mediated strain development in the penicillin-producing fungus Penicillium chrysogenum. Proceedings of the National Academy of Sciences, 110(4), doi:10.1073/pnas.1217943110

Penicillium chrysogenum is a filamentous fungus of major medical and historical importance, being the original and present-day industrial source of the antibiotic penicillin. The species has been considered asexual for more than 100 y, and despite co... Read More about Sexual reproduction and mating-type-mediated strain development in the penicillin-producing fungus Penicillium chrysogenum.