A novel Bayesian approach to accounting for uncertainty in fMRI-derived estimates of cerebral oxygen metabolism fluctuations

Simon, Aaron B.; Dubowitz, David J.; Blockley, Nicholas P.; Buxton, Richard B.

doi:10.1016/j.neuroimage.2016.01.001

All Outputs (4)

A streamlined acquisition for mapping baseline brain oxygenation using quantitative BOLD (2016)
Journal Article
Stone, A. J., & Blockley, N. P. (2017). A streamlined acquisition for mapping baseline brain oxygenation using quantitative BOLD. NeuroImage, 147, 79-88. https://doi.org/10.1016/j.neuroimage.2016.11.057

Improving the specificity of R2′ to the deoxyhaemoglobin content of brain tissue: Prospective correction of macroscopic magnetic field gradients (2016)
Journal Article
Blockley, N. P., & Stone, A. J. (2016). Improving the specificity of R2′ to the deoxyhaemoglobin content of brain tissue: Prospective correction of macroscopic magnetic field gradients. NeuroImage, 135, 253-260. https://doi.org/10.1016/j.neuroimage.2016.04.013

The reversible transverse relaxation rate, R2′, is sensitive to the deoxyhaemoglobin content of brain tissue, enabling information about the oxygen extraction fraction to be obtained. However, R2′ is also sensitive to macroscopic magnetic field gradi... Read More about Improving the specificity of R2′ to the deoxyhaemoglobin content of brain tissue: Prospective correction of macroscopic magnetic field gradients.

Measurement of oxygen extraction fraction (OEF): An optimized BOLD signal model for use with hypercapnic and hyperoxic calibration (2016)
Journal Article
Merola, A., Murphy, K., Stone, A. J., Germuska, M. A., Griffeth, V. E., Blockley, N. P., …Wise, R. G. (2016). Measurement of oxygen extraction fraction (OEF): An optimized BOLD signal model for use with hypercapnic and hyperoxic calibration. NeuroImage, 129, 159-174. https://doi.org/10.1016/j.neuroimage.2016.01.021

© 2016 The Authors. Several techniques have been proposed to estimate relative changes in cerebral metabolic rate of oxygen consumption (CMRO2) by exploiting combined BOLD fMRI and cerebral blood flow data in conjunction with hypercapnic or hyperoxic... Read More about Measurement of oxygen extraction fraction (OEF): An optimized BOLD signal model for use with hypercapnic and hyperoxic calibration.

A novel Bayesian approach to accounting for uncertainty in fMRI-derived estimates of cerebral oxygen metabolism fluctuations (2016)
Journal Article
Simon, A. B., Dubowitz, D. J., Blockley, N. P., & Buxton, R. B. (2016). A novel Bayesian approach to accounting for uncertainty in fMRI-derived estimates of cerebral oxygen metabolism fluctuations. NeuroImage, 129, 198-213. https://doi.org/10.1016/j.neuroimage.2016.01.001

Calibrated blood oxygenation level dependent (BOLD) imaging is a multimodal functional MRI technique designed to estimate changes in cerebral oxygen metabolism from measured changes in cerebral blood flow and the BOLD signal. This technique addresses... Read More about A novel Bayesian approach to accounting for uncertainty in fMRI-derived estimates of cerebral oxygen metabolism fluctuations.