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Mechanisms underlying effects of kiwifruit on intestinal function shown by MRI in healthy volunteers (2019)
Journal Article
Wilkinson-Smith, V., Dellschaft, N., Ansell, J., Hoad, C., Marciani, L., Gowland, P., & Spiller, R. (2019). Mechanisms underlying effects of kiwifruit on intestinal function shown by MRI in healthy volunteers. Alimentary Pharmacology and Therapeutics, doi:10.1111/apt.15127

Background: Chronic constipation affects approximately 17% of the population worldwide and remains an important unmet need since patients are often dissatisfied with treatment. Kiwifruit may offer an alternative to traditional laxatives and have been... Read More

Tissue cell stress response to obesity and its interaction with late gestational diet (2017)
Journal Article
Saroha, V., Dellschaft, N. S., Keisler, D. H., Gardner, D. S., Budge, H., Sebert, S. P., & Symonds, M. E. (2018). Tissue cell stress response to obesity and its interaction with late gestational diet. Reproduction, Fertility and Development, 30, doi:10.1071/RD16494. ISSN 1031-3613

Intra-uterine growth restriction in late pregnancy can contribute to adverse long term metabolic health in the offspring. We utilised an animal (sheep) model of maternal dietary manipulation in late pregnancy, combined with exposure of the offspring... Read More

Beyond obesity - thermogenic adipocytes and cardiometabolic health (2017)
Journal Article
Aldiss, P., Dellschaft, N. S., Sacks, H., Budge, H., & Symonds, M. E. (in press). Beyond obesity - thermogenic adipocytes and cardiometabolic health. Hormone Molecular Biology and Clinical Investigation, 31(2), doi:10.1515/hmbci-2017-0007. ISSN 1868-1883

The global prevalence of obesity and related cardiometabolic disease continues to increase through the 21st century. Whilst multi-factorial, obesity is ultimately caused by chronic caloric excess. However, despite numerous interventions focussing on... Read More

Effect of pre- and postnatal growth and post-weaning activity on glucose metabolism in the offspring (2015)
Journal Article
Dellschaft, N. S., Alexandre-Gouabau, M., Gardner, D. S., Antignac, J., Keisler, D. H., Budge, H., …Sebert, S. P. (2015). Effect of pre- and postnatal growth and post-weaning activity on glucose metabolism in the offspring. Journal of Endocrinology, 224(2), doi:10.1530/JOE-14-0600. ISSN 0022-0795

Maternal caloric restriction during late gestation reduces birth weight, but whether long-term adverse metabolic outcomes of intra-uterine growth retardation (IUGR) are dependent on either accelerated postnatal growth or exposure to an obesogenic env... Read More