All Outputs (4)

Simultaneous Tracking of Pseudomonas aeruginosa motility in liquid and at the Solid-Liquid Interface Reveals Differential Roles for the Flagellar Stators (2019)
Journal Article
Hook, A. L., Flewellen, J. L., Dubern, J., Carabelli, A., Zald, I. M., Berry, R. M., …Alexander, M. R. (2019). Simultaneous Tracking of Pseudomonas aeruginosa motility in liquid and at the Solid-Liquid Interface Reveals Differential Roles for the Flagellar Stators. mSystems, 4(5), Article e00390-19. https://doi.org/10.1128/mSystems.00390-19

Bacteria sense chemicals, surfaces, and other cells and move toward some and away from others. Studying how single bacterial cells in a population move requires sophisticated tracking and imaging techniques. We have established quantitative methodolo... Read More about Simultaneous Tracking of Pseudomonas aeruginosa motility in liquid and at the Solid-Liquid Interface Reveals Differential Roles for the Flagellar Stators.

Polymer microparticles with defined surface chemistry and topography mediate the formation of stem cell aggregates and cardiomyocyte function (2019)
Journal Article
Alvarez-Paino, M., Amer, M. H., Nasir, A., Cuzzucoli Crucitti, V., Thorpe, J., Burroughs, L., …Rose, F. (2019). Polymer microparticles with defined surface chemistry and topography mediate the formation of stem cell aggregates and cardiomyocyte function. ACS Applied Materials and Interfaces, 11(38), 34560-34574. https://doi.org/10.1021/acsami.9b04769

Surface-functionalized microparticles are relevant to fields spanning engineering and biomedicine, with uses ranging from cell culture to advanced cell delivery. Varying topographies of biomaterial surfaces are also being investigated as mediators of... Read More about Polymer microparticles with defined surface chemistry and topography mediate the formation of stem cell aggregates and cardiomyocyte function.

3D inkjet printing of tablets exploiting bespoke complex geometries for controlled and tuneable drug release (2017)
Journal Article
Kyobula, M., Adedeji, A., Alexander, M. R., Saleh, E., Wildman, R. D., Ashcroft, I., …Roberts, C. J. (2017). 3D inkjet printing of tablets exploiting bespoke complex geometries for controlled and tuneable drug release. Journal of Controlled Release, 261, 207-215. https://doi.org/10.1016/j.jconrel.2017.06.025

A hot melt 3D inkjet printing method with the potential to manufacture formulations in complex and adaptable geometries for the controlled loading and release of medicines is presented. This first use of a precisely controlled solvent free inkjet pri... Read More about 3D inkjet printing of tablets exploiting bespoke complex geometries for controlled and tuneable drug release.

Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers (2016)
Journal Article
Adlington, K., Nguyen, N. T., Eaves, E., Yang, J., Chang, C. Y., Li, J., …Irvine, D. J. (2016). Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers. Biomacromolecules, 17(9), 2830-2838. https://doi.org/10.1021/acs.biomac.6b00615

© 2016 American Chemical Society. Developing medical devices that resist bacterial attachment and subsequent biofilm formation is highly desirable. In this paper, we report the optimization of the molecular structure and thus material properties of a... Read More about Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers.