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Will MRI of gastrointestinal function parallel the clinical success of cine cardiac MRI? (2018)
Journal Article
Hoad, C., Clarke, C., Marciani, L., Graves, M. J., & Corsetti, M. (2018). Will MRI of gastrointestinal function parallel the clinical success of cine cardiac MRI?. British Journal of Radiology, doi:10.1259/bjr.20180433

Cine cardiac MRI is generally accepted as the “gold-standard” for functional myocardial assessment. It only took a few years after the development of commercial MRI systems for functional cardiac imaging to be developed, with electrocardiogram (ECG)-... Read More

Opioid receptors in the GI tract: targets for treatment of both diarrhea and constipation in functional bowel disorders? (2018)
Journal Article
Pannemans, J., & Corsetti, M. (2018). Opioid receptors in the GI tract: targets for treatment of both diarrhea and constipation in functional bowel disorders?. Current Opinion in Pharmacology, 43, 53-58. doi:10.1016/j.coph.2018.08.008

Opioids have been used for centuries, mostly as a sedative and to treat pain. Currently, they are used on a global scale for the treatment of acute and chronic pain in diseases as osteoarthritis, fibromyalgia, and low back pain. Binding of opioids on... Read More

Rome Foundation Working Team report on post-infection irritable bowel syndrome (2018)
Journal Article
Barbara, G., Grover, M., Bercik, P., Corsetti, M., Ghoshal, U. C., Ohman, L., & Rajilić-Stojanović, M. (2019). Rome Foundation Working Team report on post-infection irritable bowel syndrome. Gastroenterology, 156(1), 46-58.e7. doi:10.1053/j.gastro.2018.07.011

Background & Aims: The existence of postinfection irritable bowel syndrome (PI-IBS) has been substantiated by epidemiology studies conducted in diverse geographic and clinical settings. However, the available evidence has not been well summarized, an... Read More

The global impact of IBS: time to think about IBS-specific models of care? (2017)
Journal Article
Corsetti, M., & Whorwell, P. (2017). The global impact of IBS: time to think about IBS-specific models of care?. Therapeutic Advances in Gastroenterology, 10(9), 727-736. doi:10.1177/1756283x17718677

Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal (GI) disorder that can significantly erode the quality of life (QoL) of sufferers and places a major cost burden on healthcare services. This paper reviews the literature on th... Read More

Gastrointestinal and systemic monitoring of posaconazole in humans after fasted and fed state administration of a solid dispersion (2016)
Journal Article
Hens, B., Corsetti, M., Brouwers, J., & Augustijns, P. (2016). Gastrointestinal and systemic monitoring of posaconazole in humans after fasted and fed state administration of a solid dispersion. Journal of Pharmaceutical Sciences, 105(9), 2904-2912. doi:10.1016/j.xphs.2016.03.027

The purpose of this study was to explore the intraluminal behavior and systemic exposure of posaconazole in humans after oral intake of a novel delayed-release tablet (Noxafil®), containing posaconazole dispersed in a matrix of hydroxypropyl methylce... Read More