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A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults (2018)
Journal Article
Din, U., Brook, M., Selby, A. L., Quinlan, J. I., Boereboom, C., Abdullah, H., …Smith, K. (2019). A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults. Clinical Nutrition, 38(5), 2071-2078. https://doi.org/10.1016/j.clnu.2018.09.025

Age-related sarcopenia and dynapenia are associated with frailty and metabolic diseases. Resistance exercise training (RET) adjuvant to evidence-based nutritional intervention(s) have been shown as mitigating strategies. Given that HMB supplementatio... Read More about A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults.

Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training (2018)
Journal Article
Ahtiainen, J. P., Lensu, S., Ruotsalainen, I., Schumann, M., Ihalainen, J. K., Fachada, V., …Kainulainen, H. (2018). Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training. Experimental Physiology, https://doi.org/10.1113/ep087144

The purpose of this study was to determine whether rats selectively bred for low and high response to aerobic exercise training co-segregate for differences in muscle adaptations to ladder-climbing resistance training. Five high-responder (HRT) and f... Read More about Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training.

Tart cherry concentrate does not enhance muscle protein synthesis response to exercise and protein in healthy older men (2018)
Journal Article
Jackman, S. R., Brook, M. S., Pulsford, R. M., Cockcroft, E. J., Campbell, M. I., Rankin, D., …Bowtell, J. L. (2018). Tart cherry concentrate does not enhance muscle protein synthesis response to exercise and protein in healthy older men. Experimental Gerontology, 110, 202-208. https://doi.org/10.1016/j.exger.2018.06.007

Background: Oxidative stress and inflammation may contribute to anabolic resistance in response to protein and exercise in older adults. We investigated whether consumption of montmorency cherry concentrate (MCC) increased anabolic sensitivity to pro... Read More about Tart cherry concentrate does not enhance muscle protein synthesis response to exercise and protein in healthy older men.

Environmental hypoxia favors myoblast differentiation and fast phenotype but blunts activation of protein synthesis after resistance exercise in human skeletal muscle (2018)
Journal Article
Gnimassou, O., Fernández-Verdejo, R., Brook, M., Naslain, D., Balan, E., Sayda, M., …Deldicque, L. (2018). Environmental hypoxia favors myoblast differentiation and fast phenotype but blunts activation of protein synthesis after resistance exercise in human skeletal muscle. FASEB Journal, 32, https://doi.org/10.1096/fj.201800049rr

We hypothesized that a single session of resistance exercise performed in moderate hypoxic (FiO2: 14%) environmental conditions would potentiate the anabolic response during the recovery period spent in normoxia. Twenty subjects performed a 1-leg kne... Read More about Environmental hypoxia favors myoblast differentiation and fast phenotype but blunts activation of protein synthesis after resistance exercise in human skeletal muscle.