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Driving next generation manufacturing through advanced metals characterisation capability (2024)
Journal Article
Clare, A., Seita, M., Speidel, A., Collins, P., & Clark, M. (2024). Driving next generation manufacturing through advanced metals characterisation capability. Scripta Materialia, Article 116009. https://doi.org/10.1016/j.scriptamat.2024.116009

Understanding the effects of manufacturing methods upon materials has driven constant innovation for over 300 years. While our ability to fabricate metallurgical wonders extends into the annals of history our ability to understand the scientific prin... Read More about Driving next generation manufacturing through advanced metals characterisation capability.

Classification of cancer cells at the sub-cellular level by phonon microscopy using deep learning (2023)
Journal Article
Pérez-Cota, F., Martínez-Arellano, G., La Cavera III, S., Hardiman, W., Thornton, L., Fuentes-Domínguez, R., …Clark, M. (2023). Classification of cancer cells at the sub-cellular level by phonon microscopy using deep learning. Scientific Reports, 13, Article 16228. https://doi.org/10.1038/s41598-023-42793-9

There is a consensus about the strong correlation between the elasticity of cells and tissue and their normal, dysplastic, and cancerous states. However, developments in cell mechanics have not seen significant progress in clinical applications. In t... Read More about Classification of cancer cells at the sub-cellular level by phonon microscopy using deep learning.

Living cells as a biological analog of optical tweezers – a non-invasive microrheology approach (2023)
Journal Article
Hardiman, W., Clark, M., Friel, C., Huett, A., Pérez-Cota, F., Setchfield, K., …Tassieri, M. (2023). Living cells as a biological analog of optical tweezers – a non-invasive microrheology approach. Acta Biomaterialia, 166, 317-325. https://doi.org/10.1016/j.actbio.2023.04.039

Microrheology, the study of fluids on micron length-scales, promises to reveal insights into cellular biology, including mechanical biomarkers of disease and the interplay between biomechanics and cellular function. Here a minimally-invasive passive... Read More about Living cells as a biological analog of optical tweezers – a non-invasive microrheology approach.

Parallel imaging with phonon microscopy using a multi-core fibre bundle detection (2023)
Journal Article
Fuentes-Domínguez, R., Yao, M., Hardiman, W., La Cavera III, S., Setchfield, K., Pérez-Cota, F., …Clark, M. (2023). Parallel imaging with phonon microscopy using a multi-core fibre bundle detection. Photoacoustics, 31, Article 100493. https://doi.org/10.1016/j.pacs.2023.100493

In this paper, we show a proof-of-concept method to parallelise phonon microscopy measurements for cell elasticity imaging by demonstrating a 3-fold increase in acquisition speed which is limited by current acquisition hardware. Phonon microscopy is... Read More about Parallel imaging with phonon microscopy using a multi-core fibre bundle detection.

Imaging Microstructure on Optically Rough Surfaces Using Spatially Resolved Acoustic Spectroscopy (2023)
Journal Article
Li, W., Dryburgh, P., Pieris, D., Patel, R., Clark, M., & Smith, R. J. (2023). Imaging Microstructure on Optically Rough Surfaces Using Spatially Resolved Acoustic Spectroscopy. Applied Sciences, 13(6), Article 3424. https://doi.org/10.3390/app13063424

The microstructure of a material defines many of its mechanical properties. Tracking the microstructure of parts during their manufacturing is needed to ensure the designed performance can be obtained, especially for additively manufactured parts. Me... Read More about Imaging Microstructure on Optically Rough Surfaces Using Spatially Resolved Acoustic Spectroscopy.

Polarization-Sensitive Super-Resolution Phononic Reconstruction of Nanostructures (2022)
Journal Article
Fuentes-Domínguez, R., Naznin, S., La Cavera III, S., Cousins, R., Pérez-Cota, F., Smith, R. J., & Clark, M. (2022). Polarization-Sensitive Super-Resolution Phononic Reconstruction of Nanostructures. ACS Photonics, https://doi.org/10.1021/acsphotonics.1c01607

In this paper, we show for the first time the polarization-sensitive super-resolution phononic reconstruction of multiple nanostructures in a liquid environment by overcoming the diffraction limit of the optical system (1 μm). By using time-resolved... Read More about Polarization-Sensitive Super-Resolution Phononic Reconstruction of Nanostructures.

Measurement of the single crystal elasticity matrix of polycrystalline materials (2021)
Journal Article
Dryburgh, P., Li, W., Pieris, D., Fuentes-Domínguez, R., Patel, R., Smith, R. J., & Clark, M. (2022). Measurement of the single crystal elasticity matrix of polycrystalline materials. Acta Materialia, 225, Article 117551. https://doi.org/10.1016/j.actamat.2021.117551

Many engineering metals are polycrystalline, as such the elasticity, crystalline orientation and grain distribution are cardinal factors in determining the physical properties of the material. The grain distribution can be measured using a number of... Read More about Measurement of the single crystal elasticity matrix of polycrystalline materials.

Phonon imaging in 3D with a fibre probe (2021)
Journal Article
La Cavera III, S., Pérez-Cota, F., Smith, R. J., & Clark, M. (2021). Phonon imaging in 3D with a fibre probe. Light: Science and Applications, 10, Article 91. https://doi.org/10.1038/s41377-021-00532-7

We show for the first time that a single ultrasonic imaging fibre is capable of simultaneously accessing 3D spatial information and mechanical properties from microscopic objects. The novel measurement system consists of two ultrafast lasers that exc... Read More about Phonon imaging in 3D with a fibre probe.

3D phonon microscopy with sub-micron axial-resolution (2021)
Journal Article
Smith, R. J., Perez-Cota, F., Marques, L., & Clark, M. (2021). 3D phonon microscopy with sub-micron axial-resolution. Scientific Reports, 11(1), Article 3301. https://doi.org/10.1038/s41598-021-82639-w

© 2021, The Author(s). Brillouin light scattering (BLS) is an emerging method for cell imaging and characterisation. It allows elasticity-related contrast, optical resolution and label-free operation. Phonon microscopy detects BLS from laser generate... Read More about 3D phonon microscopy with sub-micron axial-resolution.

Single pixel camera methodologies for spatially resolved acoustic spectroscopy (2021)
Journal Article
Patel, R., Sharples, S. D., Clark, M., Somekh, M. G., & Li, W. (2021). Single pixel camera methodologies for spatially resolved acoustic spectroscopy. Applied Physics Letters, 118(5), Article 051102. https://doi.org/10.1063/5.0040123

Spatially resolved acoustic spectroscopy (SRAS) is a laser ultrasound technique used to determine the crystallographic orientation (i.e. microstructure) of materials through the generation and measurement of surface acoustic wave velocity on a sample... Read More about Single pixel camera methodologies for spatially resolved acoustic spectroscopy.

Design of a resonant Luneburg lens for surface acoustic waves (2020)
Journal Article
Fuentes-Domínguez, R., Yao, M., Colombi, A., Dryburgh, P., Pieris, D., Jackson-Crisp, A., …Clark, M. (2021). Design of a resonant Luneburg lens for surface acoustic waves. Ultrasonics, 111, Article 106306. https://doi.org/10.1016/j.ultras.2020.106306

© 2020 In this work we employ additive manufacturing to print a circular array of micropillars on an aluminium slab turning its top surface into a graded index metasurface for surface acoustic waves (SAW). The graded metasurface reproduces a Luneburg... Read More about Design of a resonant Luneburg lens for surface acoustic waves.

Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells (2020)
Journal Article
Pérez-Cota, F., Fuentes-Domínguez, R., La Cavera III, S., Hardiman, W., Yao, M., Setchfield, K., …Clark, M. (2020). Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells. Journal of Applied Physics, 128(16), Article 160902. https://doi.org/10.1063/5.0023744

© 2020 Author(s). Characterization of the elasticity of biological cells is growing as a new way to gain insight into cell biology. Cell mechanics are related to most aspects of cellular behavior, and applications in research and medicine are broad.... Read More about Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells.

Tailored elastic surface to body wave Umklapp conversion (2020)
Journal Article
Chaplain, G. J., De Ponti, J. M., Colombi, A., Fuentes-Dominguez, R., Dryburg, P., Pieris, D., …Craster, R. V. (2020). Tailored elastic surface to body wave Umklapp conversion. Nature Communications, 11(1), Article 3267. https://doi.org/10.1038/s41467-020-17021-x

© 2020, The Author(s). Elastic waves guided along surfaces dominate applications in geophysics, ultrasonic inspection, mechanical vibration, and surface acoustic wave devices; precise manipulation of surface Rayleigh waves and their coupling with pol... Read More about Tailored elastic surface to body wave Umklapp conversion.

Characterising the size and shape of metallic nano-structures by their acoustic vibrations (2020)
Journal Article
Fuentes-Domínguez, R., Naznin, S., Marques, L., Pérez-Cota, F., Smith, R. J., & Clark, M. (2020). Characterising the size and shape of metallic nano-structures by their acoustic vibrations. Nanoscale, 12(26), 14230-14236. https://doi.org/10.1039/d0nr03410j

© 2020 The Royal Society of Chemistry. The characterisation of metallic nano-structures is of great importance as their optical properties are strongly dependent on their size and shape. Inaccurate size or shape characterisation can result in mislead... Read More about Characterising the size and shape of metallic nano-structures by their acoustic vibrations.

Determining the crystallographic orientation of hexagonal crystal structure materials with surface acoustic wave velocity measurements (2020)
Journal Article
Lain'e, S. J., Dryburgh, P., Smith, R. J., Marrow, P., Lainé, S. J., Sharples, S. D., …Li, W. (2020). Determining the crystallographic orientation of hexagonal crystal structure materials with surface acoustic wave velocity measurements. Ultrasonics, 108, Article 106171. https://doi.org/10.1016/j.ultras.2020.106171

© 2020 Throughout our engineered environment, many materials exhibit a crystalline lattice structure. The orientation of such lattices is crucial in determining functional properties of these structures, including elasticity and magnetism. Hence, too... Read More about Determining the crystallographic orientation of hexagonal crystal structure materials with surface acoustic wave velocity measurements.

Apparent attenuation by opto-acoustic defocus in phonon microscopy (2020)
Journal Article
Fuentes-Domínguez, R., La Cavera, S., Pérez-Cota, F., La Cavera III, S., Naznin, S., Fuentes-Dominguez, R., …Clark, M. (2020). Apparent attenuation by opto-acoustic defocus in phonon microscopy. Photoacoustics, 19, Article 100180. https://doi.org/10.1016/j.pacs.2020.100180

© 2020 The Author(s) Understanding the mechanical properties of biological cells is a challenging problem for the life sciences partly because there are limited methods for mapping elasticity with high resolution. Phonon microscopy is a form of Brill... Read More about Apparent attenuation by opto-acoustic defocus in phonon microscopy.

Laser Induced Phased Arrays (LIPA) to detect nested features in additively manufactured components (2019)
Journal Article
Pieris, D., Stratoudaki, T., Javadi, Y., Lukacs, P., Catchpole-Smith, S., Wilcox, P. D., …Clark, M. (2020). Laser Induced Phased Arrays (LIPA) to detect nested features in additively manufactured components. Materials and Design, 187, Article 108412. https://doi.org/10.1016/j.matdes.2019.108412

© 2019 The Authors. Additive manufacturing (AM) has the capability to build complex parts with internal features, which have many advantages over conventionally manufactured parts. This makes AM an alternative for advanced manufacturing sectors. AM c... Read More about Laser Induced Phased Arrays (LIPA) to detect nested features in additively manufactured components.

Wireless Nanobioelectronics for Electrical Intracellular Sensing (2019)
Journal Article
Sanjuan-Alberte, P., Jain, A., Shaw, A. J., Abayzeed, S. A., Domínguez, R. F., Alea-Reyes, M. E., …Rawson, F. J. (2019). Wireless Nanobioelectronics for Electrical Intracellular Sensing. ACS Applied Nano Materials, 2(10), 6397-6408. https://doi.org/10.1021/acsanm.9b01374

For the field of bioelectronics to make an impact on healthcare, there is an urgent requirement for the development of “wireless” electronic systems to enable modulation of chemistry inside of cells. Herein we report on an intracellular wireless elec... Read More about Wireless Nanobioelectronics for Electrical Intracellular Sensing.

Time resolved Brillouin fiber-spectrometer (2019)
Journal Article
La Cavera, S., Pérez-Cota, F., Fuentes-Domínguez, R., Smith, R. J., & Clark, M. (2019). Time resolved Brillouin fiber-spectrometer. Optics Express, 27(18), 25064-25071. https://doi.org/10.1364/OE.27.025064

This report introduces a novel time resolved Brillouin spectrometer, consisting of an opto-acoustic transducer which resides on the tip of a single-mode optical fiber of arbitrary length with 125 µm outer diameter and 5 µm sensing diameter. Demonstra... Read More about Time resolved Brillouin fiber-spectrometer.

Spatially resolved acoustic spectroscopy (SRAS) microstructural imaging (2019)
Journal Article
Clark, M., Clare, A., Dryburgh, P., Li, W., Patel, R., Pieris, D., …Smith, R. (2019). Spatially resolved acoustic spectroscopy (SRAS) microstructural imaging. AIP Conference Proceedings, 2102, Article 020001. https://doi.org/10.1063/1.5099705

© 2019 Author(s). Spatially resolved acoustic spectroscopy (SRAS) is an acoustic microscopy technique that can image the microstructure and measure the crystallographic orientation of grains or crystals in the material. It works by measuring the velo... Read More about Spatially resolved acoustic spectroscopy (SRAS) microstructural imaging.