All Outputs (4)

Impact of neospora caninum infection on the bioenergetics and transcriptome of cerebrovascular endothelial cells (2020)
Journal Article
Elsheikha, H. M., Alkurashi, M., Palfreman, S., Castellanos, M., Kong, K., Ning, E., …MacNaughtan, W. (2020). Impact of neospora caninum infection on the bioenergetics and transcriptome of cerebrovascular endothelial cells. Pathogens, 9(9), Article 710. https://doi.org/10.3390/pathogens9090710

In this work, the effects of the protozoan Neospora caninum on the bioenergetics, chemical composition, and elemental content of human brain microvascular endothelial cells (hBMECs) were investigated. We showed that N. caninum can impair cell mitocho... Read More about Impact of neospora caninum infection on the bioenergetics and transcriptome of cerebrovascular endothelial cells.

Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells (2019)
Journal Article
Ahmed, M., Jinks, N., Babaei-Jadidi, R., Kashfi, H., Castellanos-Uribe, M., May, S. T., …Nateri, A. S. (2019). Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells. Cancers, 12(1), Article 106. https://doi.org/10.3390/cancers12010106

Tumour-promoting inflammation is involved in colorectal cancer (CRC) development and therapeutic resistance. However, the antibiotics and antibacterial drugs and signalling that regulate the potency of anticancer treatment upon forced differentiation... Read More about Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells.

Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner (2016)
Journal Article
Kroes, A., Broekgaarden, C., Castellanos Uribe, M., May, S., van Loon, J. J., & Dicke, M. (2017). Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner. Oecologia, 183(1), 107-120. https://doi.org/10.1007/s00442-016-3758-3

Plants are commonly attacked by multiple herbivorous species. Yet, little is known about transcriptional patterns underlying plant responses to multiple insect attackers feeding simultaneously. Here, we assessed= transcriptomic responses of Arabidops... Read More about Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner.

The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana (2015)
Journal Article
Seguela-Arnaud, M., Smith, C., Castellanos Uribe, M., May, S., Fischl, H., McKenzie, N., & Bevan, M. W. (2015). The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana. BMC Plant Biology, 15(1), Article 215. https://doi.org/10.1186/s12870-015-0592-4

Background: Plant cell walls are dynamic structures involved in all aspects of plant growth, environmental interactions and defense responses, and are the most abundant renewable source of carbon-containing polymers on the planet. To balance rigidity... Read More about The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana.