All Outputs (11)

Translation of plasma technology from the lab to the food industry (2017)
Journal Article
Cullen, P., Lalor, J., Scally, L., Boehm, D., Milosavljević, V., Bourke, P., & Keener, K. (2018). Translation of plasma technology from the lab to the food industry. Plasma Processes and Polymers, 15(2), Article 1700085. https://doi.org/10.1002/ppap.201700085

The potential of cold plasma as a food processing aid has been demonstrated for a range of processes and products. The potential applications of plasma technology are extensive and include: microbial decontamination, pest control, toxin elimination,... Read More about Translation of plasma technology from the lab to the food industry.

The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria (2016)
Journal Article
Rauch, C., Cherkaoui-Rbati, M., Egan, S. A., & Leigh, J. A. (2017). The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria. BBA - Biomembranes, 1859(2), https://doi.org/10.1016/j.bbamem.2016.12.002

Background: The anionic-polyelectrolyte nature of the wall of Gram-positive bacteria has long been suspected to be involved in homeostasis of essential cations and bacterial growth. A better understanding of the coupling between the biophysics and th... Read More about The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria.

Palimpsest: improving assisted curation of loco-specific literature (2016)
Journal Article
Alex, B., Grover, C., Oberlander, J., Thomson, T., Anderson, M., Loxley, J., …Zhou, K. (2017). Palimpsest: improving assisted curation of loco-specific literature. Digital Scholarship in the Humanities, 32(Supp 1), Article i4-i16. https://doi.org/10.1093/llc/fqw050

Text mining and information visualization techniques applied to large-scale historical and literary document collections have enabled new types of humanities research. The assumption behind such efforts is often that trends will emerge from the analy... Read More about Palimpsest: improving assisted curation of loco-specific literature.

Investigating splicing variants uncovered by next-generation sequencing the Alzheimer’s disease candidate genes, CLU, PICALM, CR1, ABCA7, BIN1, the MS4A locus, CD2AP, EPHA1 and CD33 (2016)
Journal Article
Clement, N., Braae, A., Turton, J., Lord, J., Guetta-Baranes, T., Medway, C., …Morgan, K. (in press). Investigating splicing variants uncovered by next-generation sequencing the Alzheimer’s disease candidate genes, CLU, PICALM, CR1, ABCA7, BIN1, the MS4A locus, CD2AP, EPHA1 and CD33. Journal of Alzheimer's Disease and Parkinsonism, 6(6), https://doi.org/10.4172/2161-0460.1000276

Late onset Alzheimer’s disease (LOAD), the most common cause of late onset dementia, has a strong genetic component. To date, 21 disease-risk loci have been identified through genome wide association studies (GWAS). However, the causative functional... Read More about Investigating splicing variants uncovered by next-generation sequencing the Alzheimer’s disease candidate genes, CLU, PICALM, CR1, ABCA7, BIN1, the MS4A locus, CD2AP, EPHA1 and CD33.

Brown adipose tissue activation as measured by infrared thermography by mild anticipatory psychological stress in lean healthy females (2016)
Journal Article
Robinson, L. J., Law, J., Symonds, M. E., & Budge, H. (2016). Brown adipose tissue activation as measured by infrared thermography by mild anticipatory psychological stress in lean healthy females. Experimental Physiology, 101(4), 549-557. https://doi.org/10.1113/EP085642

Brown adipose tissue (BAT) has been implicated in the pathogenesis of obesity, type 2 diabetes and the metabolic syndrome and is a potential therapeutic target. Brown adipose tissue can have a significant impact on energy balance and glucose homeosta... Read More about Brown adipose tissue activation as measured by infrared thermography by mild anticipatory psychological stress in lean healthy females.

Streptococcus uberis strains isolated from the bovine mammary gland evade immune recognition by mammary epithelial cells, but not of macrophages (2016)
Journal Article
Günther, J., Czabanska, A., Bauer, I., Leigh, J. A., Holst, O., & Seyfert, H. (2016). Streptococcus uberis strains isolated from the bovine mammary gland evade immune recognition by mammary epithelial cells, but not of macrophages. Veterinary Research, 47(13), https://doi.org/10.1186/s13567-015-0287-8

Streptococcus uberis is frequently isolated from the mammary gland of dairy cattle. Infection with some strains can induce mild subclinical inflammation whilst others induce severe inflammation and clinical mastitis. We compared here the inflammatory... Read More about Streptococcus uberis strains isolated from the bovine mammary gland evade immune recognition by mammary epithelial cells, but not of macrophages.

Heritability of attractiveness to mosquitoes (2015)
Journal Article
Mandela Fernández-Grandon, G., Gezan, S. A., Armour, J. A., Pickett, J. A., & Logan, J. G. (in press). Heritability of attractiveness to mosquitoes. PLoS ONE, 10(4), Article e0122716. https://doi.org/10.1371/journal.pone.0122716

Female mosquitoes display preferences for certain individuals over others, which is determined by differences in volatile chemicals produced by the human body and detected by mosquitoes. Body odour can be controlled genetically but the existence of a... Read More about Heritability of attractiveness to mosquitoes.

Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field (2014)
Journal Article
Rauch, C., & Leigh, J. A. (in press). Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field. BBA - General Subjects, 1850(4), https://doi.org/10.1016/j.bbagen.2014.12.004

Background: Electroporation is a method of choice to transform living cells. The ability of electroporation to transfer small or large chemicals across the lipid bilayer membrane of eukaryotic cells or Gram-negative bacteria relies on the formation o... Read More about Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field.

Two distinct populations of Bovine IL-17+ T-cells can be induced and WC1+IL-17+?? T-cells are effective killers of protozoan parasites (2014)
Journal Article
Peckham, R., Brill, R., Foster, D. S., Bowen, A., Leigh, J. A., Coffey, T. J., & Flynn, R. J. (2014). Two distinct populations of Bovine IL-17+ T-cells can be induced and WC1+IL-17+?? T-cells are effective killers of protozoan parasites. Scientific Reports, 4, Article 5431. https://doi.org/10.1038/srep05431

IL-17 has emerged as a key player in the immune system, exhibiting roles in protection from infectious diseases and promoting inflammation in autoimmunity. Initially thought to be CD4 T-cell-derived, the sources of IL-17 are now known to be varied an... Read More about Two distinct populations of Bovine IL-17+ T-cells can be induced and WC1+IL-17+?? T-cells are effective killers of protozoan parasites.

Insight into lithium transport in lithium nitridometallate battery materials from muon spin relaxation (2013)
Journal Article
Powell, A. S., Stoeva, Z., Lord, J. S., Smith, R. I., Gregory, D. H., & Titman, J. J. (2013). Insight into lithium transport in lithium nitridometallate battery materials from muon spin relaxation. Physical Chemistry Chemical Physics, 15(3), https://doi.org/10.1039/c2cp43318d

Muon spin relaxation and powder neutron diffraction have been combined to study three lithium cobalt nitride battery materials. Neutron diffraction shows that these retain the P6/mmm space group of Li3N with Co located only on Li(1) sites. The lattic... Read More about Insight into lithium transport in lithium nitridometallate battery materials from muon spin relaxation.

Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions (2012)
Journal Article
Lord, J., Turton, J., Medway, C., Shi, H., Brown, K., Lowe, J., …Morgan, K. (2012). Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions. International Journal of Molecular Epidemiology and Genetics, IJMEG, 3(4),

CLU, PICALM and CR1 were identified as genetic risk factors for late onset Alzheimer’s disease (AD) in two large genome wide association studies (GWAS) published in 2009, but the variants that convey this alteration in disease risk, and how the genes... Read More about Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions.