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All Outputs (4)

Low-Power Sonication Can Alter Extracellular Vesicle Size and Properties (2021)
Journal Article
Nizamudeen, Z. A., Xerri, R., Parmenter, C., Suain, K., Markus, R., Chakrabarti, L., & Sottile, V. (2021). Low-Power Sonication Can Alter Extracellular Vesicle Size and Properties. Cells, 10(9), Article 2413. https://doi.org/10.3390/cells10092413

Low-power sonication is widely used to disaggregate extracellular vesicles (EVs) after isolation, however, the effects of sonication on EV samples beyond dispersion are unclear. The present study analysed the characteristics of EVs collected from mes... Read More about Low-Power Sonication Can Alter Extracellular Vesicle Size and Properties.

A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats (2019)
Journal Article
Pollard, A. K., Ingram, T. L., Ortori, C. A., Shephard, F., Brown, M., Liddell, S., …Chakrabarti, L. (2019). A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats. Aging, 11(6), 1664-1685. https://doi.org/10.18632/aging.101861

It is accepted that smaller mammals with higher metabolic rates have shorter lifespans. The very few species that do not follow these rules can give insights into interesting differences. The recorded maximum lifespans of bats are exceptional - over... Read More about A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats.

Mouse mitochondrial lipid composition is defined by age in brain and muscle (2017)
Journal Article
Pollard, A. K., Ortori, C. A., Stöger, R., Barrett, D. A., & Chakrabarti, L. (in press). Mouse mitochondrial lipid composition is defined by age in brain and muscle. Aging, 9(3), https://doi.org/10.18632/aging.101204

Functionality of the lipid rich mitochondrial organelle declines with increased age. Recent advances in lipidomic technologies allowed us to perform a global characterisation of lipid composition in two different tissue types and age ranges. Ultra-hi... Read More about Mouse mitochondrial lipid composition is defined by age in brain and muscle.