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3D phonon microscopy with sub-micron axial-resolution (2021)
Journal Article
Smith, R. J., Perez-Cota, F., Marques, L., & Clark, M. (2021). 3D phonon microscopy with sub-micron axial-resolution. Scientific Reports, 11(1), Article 3301. https://doi.org/10.1038/s41598-021-82639-w

© 2021, The Author(s). Brillouin light scattering (BLS) is an emerging method for cell imaging and characterisation. It allows elasticity-related contrast, optical resolution and label-free operation. Phonon microscopy detects BLS from laser generate... Read More about 3D phonon microscopy with sub-micron axial-resolution.

Highly sensitive label-free antibody detection using a long period fibre grating sensor (2018)
Journal Article
Liu, L., Marques, L., Correia, R., Morgan, S. P., Lee, S., Tighe, P. J., …Korposh, S. (2018). Highly sensitive label-free antibody detection using a long period fibre grating sensor. Sensors and Actuators B: Chemical, 271, 24-32. https://doi.org/10.1016/j.snb.2018.05.109

An optical fibre long period grating (LPG) biosensor is appealing in the detection of biomolecules because of the high sensitivity, label-free and real-time measurement. The miniaturized size, ability of remote sensing and immunity to electromagnetic... Read More about Highly sensitive label-free antibody detection using a long period fibre grating sensor.

Cell imaging by phonon microscopy: sub-optical wavelength ultrasound for non-invasive imaging (2017)
Journal Article
Perez-Cota, F., Smith, R. J., Moradi, E., Leija, A. L., Velickovic, K., Marques, L., …Clark, M. (2017). Cell imaging by phonon microscopy: sub-optical wavelength ultrasound for non-invasive imaging

The mechanical properties of cells play an important role in cell function and behavior. This paper presents recent developments that have enabled the use of laser-generated phonons (ultrasound) with sub-optical wavelengths to look inside living cell... Read More about Cell imaging by phonon microscopy: sub-optical wavelength ultrasound for non-invasive imaging.

Size characterisation method and detection enhancement of plasmonic nanoparticles in a pump–probe system (2017)
Journal Article
Fuentes-Domínguez, R., Smith, R. J., Pérez-Cota, F., Marques, L., Peña-Rodríguez, O., & Clark, M. (2017). Size characterisation method and detection enhancement of plasmonic nanoparticles in a pump–probe system. Applied Sciences, 7(8), Article 819. https://doi.org/10.3390/app7080819

The optical resonance of metal nanoparticles can be used to enhance the generation and detection of their main vibrational mode. In this work, we show that this method allows the accurate characterisation of the particle’s size because the vibrationa... Read More about Size characterisation method and detection enhancement of plasmonic nanoparticles in a pump–probe system.

High resolution 3D imaging of living cells with sub-optical wavelength phonons (2016)
Journal Article
Perez-Cota, F., Smith, R. J., Moradi, E., Marques, L., Webb, K. F., & Clark, M. (2016). High resolution 3D imaging of living cells with sub-optical wavelength phonons. Scientific Reports, 6, Article 39326. https://doi.org/10.1038/srep39326

Label-free imaging of living cells below the optical diffraction limit poses great challenges for optical microscopy. Biologically relevant structural information remains below the Rayleigh limit and beyond the reach of conventional microscopes. Supe... Read More about High resolution 3D imaging of living cells with sub-optical wavelength phonons.

Novel highly sensitive protein sensors based on tapered optical fibres modified with Au-based nanocoatings (2016)
Journal Article
Urrutia, A., Bojan, K., Marques, L., Mullaney, K., Goicoechea, J., James, S., …Tatam, R. (in press). Novel highly sensitive protein sensors based on tapered optical fibres modified with Au-based nanocoatings. Journal of Sensors, 2016, https://doi.org/10.1155/2016/8129387

Novel protein sensors based on tapered optical fibres modified with Au coatings deposited using two different procedures are proposed. Au-based coatings are deposited onto a nonadiabatic tapered optical fibre using (i) a novel facile method composed... Read More about Novel highly sensitive protein sensors based on tapered optical fibres modified with Au-based nanocoatings.

Thin-film optoacoustic transducers for the subcellular Brillouin oscillation imaging of individual biological cells (2015)
Journal Article
Perez-Cota, F., Smith, R. J., Moradi, E., Marques, L., Webb, K. F., & Clark, M. (2015). Thin-film optoacoustic transducers for the subcellular Brillouin oscillation imaging of individual biological cells. Applied Optics, 54(28), https://doi.org/10.1364/AO.54.008388

Mechanical characterisation and imaging of biological tissue has piqued interest in the applicability to cell and tissue biology. One method, based on detection of Brillouin oscillations, has already lead to demonstrations on biological cells using u... Read More about Thin-film optoacoustic transducers for the subcellular Brillouin oscillation imaging of individual biological cells.

Highly sensitive optical fibre long period grating biosensor anchored with silica core gold shell nanoparticles (2015)
Journal Article
Marques, L. M., Hernandez, F. U., James, S. W., Morgan, S. P., Clark, M., Tatam, R. P., & Korposh, S. (2016). Highly sensitive optical fibre long period grating biosensor anchored with silica core gold shell nanoparticles. Biosensors and Bioelectronics, 75, https://doi.org/10.1016/j.bios.2015.08.046

An optical fibre long period grating (LPG), modified with a coating of silica core gold shell (SiO2:Au) nanoparticles (NPs) deposited using the layer-by-layer method, was employed for the development of a biosensor. The SiO2:Au NPs were electrostatic... Read More about Highly sensitive optical fibre long period grating biosensor anchored with silica core gold shell nanoparticles.

Facile approach to generating polymeric nanoarrays containing populations of nanoparticles (2015)
Journal Article
Marques, L., Chen, X., Roberts, C. J., Clark, M., & Aylott, J. W. (2015). Facile approach to generating polymeric nanoarrays containing populations of nanoparticles. Micro and Nano Letters, 10(8), 378-383. doi:10.1049/mnl.2015.0041

The production of nanoarrays containing a population of entrapped, heterogeneous nanoparticles is reported. The nanoarray consists of a nanoporous film with pores of diameter 60-180 nm, formed from the phase separation of two immiscible polymers: pol... Read More about Facile approach to generating polymeric nanoarrays containing populations of nanoparticles.

Optically excited nanoscale ultrasonic transducers (2015)
Journal Article
Smith, R. J., Cota, F. P., Marques, L., Chen, X., Arca, A., Webb, K., …Clark, M. (2015). Optically excited nanoscale ultrasonic transducers. Journal of the Acoustical Society of America, 137(1), 219-227. https://doi.org/10.1121/1.4904487

© 2015 Acoustical Society of America. In order to work at higher ultrasonic frequencies, for instance, to increase the resolution, it is necessary to fabricate smaller and higher frequency transducers. This paper presents an ultrasonic transducer cap... Read More about Optically excited nanoscale ultrasonic transducers.

CHOTs optical transducers (2011)
Journal Article
Arca, A., Aylott, J., Marques, L., Clark, M., Somekh, M., Smith, R., …Chen, X. (2011). CHOTs optical transducers. Nondestructive Testing and Evaluation, 26(3-4), 353-366. https://doi.org/10.1080/10589759.2011.573555

Laser ultrasonics conventionally use direct absorption in the sample to generate ultrasound and monitor the sample to detect the ultrasound. However, in some circumstances there are significant advantages to using an optical transducer - a device to... Read More about CHOTs optical transducers.