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All Outputs (5)

Use of biochemical tests of placental function for improving pregnancy outcome (2015)
Journal Article
Heazell, A. E., Whitworth, M., Duley, L., & Thornton, J. (2015). Use of biochemical tests of placental function for improving pregnancy outcome. Cochrane Library, 2015(11), Article CD011202. https://doi.org/10.1002/14651858.CD011202.pub2

BACKGROUND: The placenta has an essential role in determining the outcome of pregnancy. Consequently, biochemical measurement of placentally-derived factors has been suggested as a means to improve fetal and maternal outcome of pregnancy. OBJ... Read More about Use of biochemical tests of placental function for improving pregnancy outcome.

Cord pilot trial: update to randomised trial protocol (2015)
Journal Article
on behalf of the Cord Pilot Trial Collaborative Group, , Bradshaw, L. E., Pushpa-Rajah, A., Dorling, J., Mitchell, E. J., & Duley, L. (2015). Cord pilot trial: update to randomised trial protocol. Trials, 16(1), 1-3. https://doi.org/10.1186/s13063-015-0936-2

Background: The Cord Pilot Trial aimed to assess the feasibility of conducting a large UK randomised trial to compare the effects of alternative polices for timing of cord clamping (immediate within 20 seconds or deferred after at least 2 minutes) fo... Read More about Cord pilot trial: update to randomised trial protocol.

Facilitating return to work through early specialist health-based interventions (FRESH): Protocol for a feasibility randomised controlled trial (2015)
Journal Article
Radford, K. A., Phillips, J., Jones, T., Gibson, A., Sutton, C., Watkins, C., …Shakespeare, D. (2015). Facilitating return to work through early specialist health-based interventions (FRESH): Protocol for a feasibility randomised controlled trial. Pilot and Feasibility Studies, 1, Article 24. https://doi.org/10.1186/s40814-015-0017-z

© 2015 Radford et al. Background: Over one million people sustain traumatic brain injury each year in the UK and more than 10 % of these are moderate or severe injuries, resulting in cognitive and psychological problems that affect the ability to wor... Read More about Facilitating return to work through early specialist health-based interventions (FRESH): Protocol for a feasibility randomised controlled trial.

Safety and efficacy of intensive vs. guideline antiplatelet therapy in high-risk patients with recent ischemic stroke or transient ischemic attack: rationale and design of the Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke (TARDIS) trial (ISRCTN47823388) (2015)
Journal Article
Beridze, M., Christensen, H., Dineen, R. A., Duley, L., Heptinstall, S., James, M., …Bath, P. M. (2015). Safety and efficacy of intensive vs. guideline antiplatelet therapy in high-risk patients with recent ischemic stroke or transient ischemic attack: rationale and design of the Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke (TARDIS) trial (ISRCTN47823388). International Journal of Stroke, 10(7), https://doi.org/10.1111/ijs.12538

RATIONALE: The risk of recurrence following a stroke or transient ischemic attack is high, especially immediately after the event. HYPOTHESIS: Because two antiplatelet agents are superior to one in patients with non-cardioembolic events, more... Read More about Safety and efficacy of intensive vs. guideline antiplatelet therapy in high-risk patients with recent ischemic stroke or transient ischemic attack: rationale and design of the Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke (TARDIS) trial (ISRCTN47823388).

Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation (2015)
Journal Article
Lim, W. S., Brittain, C., Duley, L., Edwards, S., Gordon, S., Montgomery, A., …Wootton, D. (2015). Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation. Health Technology Assessment, 19(16), https://doi.org/10.3310/hta19160

Background: There are no completed randomised trials of the use of corticosteroids in patients with severe influenza infection. Corticosteroid use in influenza is widespread, non-systematic and marked by controversy. A recent meta-analysis of observa... Read More about Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation.