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3D chemical characterization of frozen hydrated hydrogels using ToF-SIMS with argon cluster sputter depth profiling (2015)
Journal Article
Taylor, M., Scurr, D., Lutolf, M., Buttery, L. D., Zelzer, M., & Alexander, M. R. (2015). 3D chemical characterization of frozen hydrated hydrogels using ToF-SIMS with argon cluster sputter depth profiling. Biointerphases, 11(2), doi:10.1116/1.4928209. ISSN 1934-8630

Hydrogels have been used extensively in bioengineering as artificial cell culture supports. Investigation of the interrelationship between cellular response to the hydrogel and its chemistry ideally requires methods that allow characterization withou... Read More

Precision assembly of complex cellular microenvironments using holographic optical tweezers (2015)
Journal Article
Kirkham, G. R., Britchford, E., Upton, T., Ware, J., Gibson, G., Devaud, Y., …Shakesheff, K. M. (2015). Precision assembly of complex cellular microenvironments using holographic optical tweezers. Scientific Reports, 5, doi:10.1038/srep08577. ISSN 2045-2322

The accurate study of cellular microenvironments is limited by the lack of technologies that can manipulate cells in 3D at a sufficiently small length scale. The ability to build and manipulate multicellular microscopic structures will facilitate a m... Read More