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Correlation between breast cancer and lifestyle within the Gulf Cooperation Council countries: A systematic review (2020)
Journal Article
Tanner, L. T. A., & Cheung, K. L. (2020). Correlation between breast cancer and lifestyle within the Gulf Cooperation Council countries: A systematic review. World Journal of Clinical Oncology, 11(4), 217-242. https://doi.org/10.5306/wjco.v11.i4.217

BACKGROUND In the six Gulf Cooperation Council countries (GCCCs), Bahrain, Saudi Arabia, Kuwait, Oman, Qatar and the United Arab Emirates, breast cancer (BC) is the greatest cause of cancer incidence and mortality. Obesity and physical inactivity ar... Read More about Correlation between breast cancer and lifestyle within the Gulf Cooperation Council countries: A systematic review.

Treatment strategies and survival outcomes in breast cancer (2020)
Journal Article
Cheung, K. L. (2020). Treatment strategies and survival outcomes in breast cancer. Cancers, 12(3), https://doi.org/10.3390/cancers12030735

Treatment strategies for breast cancer are wide-ranging and often based on a multi-modality approach, depending on the stage and biology of the tumour and the acceptance and tolerance of the patient. They may include surgery, radiotherapy, and system... Read More about Treatment strategies and survival outcomes in breast cancer.

Treatment strategies and survival outcomes in older women with breast cancer: a comparative study between the FOCUS cohort and Nottingham cohort (2018)
Journal Article
Schuil, H., Derks, M., Liefers, G., Portielje, J., van de Velde, C., Syed, B., …Bastiaannet, E. (in press). Treatment strategies and survival outcomes in older women with breast cancer: a comparative study between the FOCUS cohort and Nottingham cohort. Journal of Geriatric Oncology, https://doi.org/10.1016/j.jgo.2018.05.004

Objective: Clinical trials investigating breast cancer treatment often exclude or misrepresent older adults. This study compares treatment patterns and survival of older women diagnosed with breast cancer between a Dutch and a British observational c... Read More about Treatment strategies and survival outcomes in older women with breast cancer: a comparative study between the FOCUS cohort and Nottingham cohort.

Fulvestrant for the treatment of advanced breast cancer (2018)
Journal Article
Blackburn, S. A., Parks, R. M., & Cheung, K. (2018). Fulvestrant for the treatment of advanced breast cancer. Expert Review of Anticancer Therapy, 18(7), 619-628. https://doi.org/10.1080/14737140.2018.1473038

Introduction: The current issues with endocrine therapy for treatment of advanced breast cancer include balance of efficacy of therapy versus tolerability as well as hormone resistance. The efficacy of fulvestrant, a selective oestrogen receptor degr... Read More about Fulvestrant for the treatment of advanced breast cancer.

Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome (2017)
Journal Article
Syed, B. M., Morgan, D., Setty, T., Green, A. R., Paish, E. C., Ellis, I. O., & Cheung, K. (2017). Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome. PLoS ONE, 12(12), Article e0188528. https://doi.org/10.1371/journal.pone.0188528

Background Older women are at the greatest risk of breast cancer development and a considerable number present with comorbidities. Although the majority of breast cancers in this age group express oestrogen receptor (ER), which makes endocrine the... Read More about Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome.

Controversial issues in the management of older adults with early breast cancer (2017)
Journal Article
Mislang, A. R., Cheung, K., Hamaker, M. E., Kunkler, I., Markopoulos, C., Orecchia, R., …Biganzoli, L. (in press). Controversial issues in the management of older adults with early breast cancer. Journal of Geriatric Oncology, https://doi.org/10.1016/j.jgo.2017.05.004

It is well recognized that the incidence of breast cancer increases significantly with age. Despite this, older people remain under-represented in many clinical trials and their management relies on extrapolation of data from younger patients. Provid... Read More about Controversial issues in the management of older adults with early breast cancer.

Axillary reverse mapping in N0 patients requiring sentinel lymph node biopsy: a systematic review of the literature and necessity of a randomised study (2017)
Journal Article
Parks, R., & Cheung, K. (2017). Axillary reverse mapping in N0 patients requiring sentinel lymph node biopsy: a systematic review of the literature and necessity of a randomised study. Breast, 33, https://doi.org/10.1016/j.breast.2017.02.019

Objectives: Axillary reverse mapping (ARM) is a technique to map and preserve arm lymphatics which may be damaged during surgery, resulting in lymphoedema. This work systematically reviews the incidence of lymphoedema following sentinel lymph node bi... Read More about Axillary reverse mapping in N0 patients requiring sentinel lymph node biopsy: a systematic review of the literature and necessity of a randomised study.

What influences healthcare professionals' treatment preferences for older women with operable breast cancer?: an application of the discrete choice experiment (2017)
Journal Article
Morgan, J., Walters, S., Collins, K., Robinson, T., Cheung, K., Audisio, R., …Wyld, L. (2017). What influences healthcare professionals' treatment preferences for older women with operable breast cancer?: an application of the discrete choice experiment. EJSO - European Journal of Surgical Oncology, 43(7), https://doi.org/10.1016/j.ejso.2017.01.012

Introduction Primary endocrine therapy (PET) is used variably in the UK as an alternative to surgery for older women with operable breast cancer. Guidelines state that only patients with “significant comorbidity” or “reduced life expectancy” shoul... Read More about What influences healthcare professionals' treatment preferences for older women with operable breast cancer?: an application of the discrete choice experiment.

Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer (2016)
Journal Article
Hunt, K. K., Karakas, C., Ha, M. J., Biernacka, A., Yi, M., Sahin, A., …Keyomarsi, K. (2017). Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer. Clinical Cancer Research, 23(12), 2991-3002. https://doi.org/10.1158/1078-0432.ccr-16-2217

Background: Low-molecular-weight-cyclin E (LMW-E) detected by Western blot, predicts for reduced breast cancer survival, however, it is impractical for clinical use. LMW-E lacks a nuclear localization signal which leads to accumulation in the cytopla... Read More about Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer.