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All Outputs (13)

Seasonality as a driver of pH1N12009 influenza vaccination campaign impact (2023)
Journal Article
Bolton, K. J., McCaw, J. M., Dafilis, M. P., McVernon, J., & Heffernan, J. M. (2023). Seasonality as a driver of pH1N12009 influenza vaccination campaign impact. Epidemics, 45, Article 100730. https://doi.org/10.1016/j.epidem.2023.100730

Although the most recent respiratory virus pandemic was triggered by a Coronavirus, sustained and elevated prevalence of highly pathogenic avian influenza viruses able to infect mammalian hosts highlight the continued threat of pandemics of influenza... Read More about Seasonality as a driver of pH1N12009 influenza vaccination campaign impact.

Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university (2023)
Journal Article
Fairbanks, E. L., Bolton, K. J., Jia, R., Figueredo, G. P., Knight, H., & Vedhara, K. (2023). Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university. Epidemics, 43, Article 100688. https://doi.org/10.1016/j.epidem.2023.100688

We survey 62 users of a university asymptomatic SARS-CoV-2 testing service on details of their activities, protective behaviours and contacts in the 7 days prior to receiving a positive or negative SARS-CoV-2 PCR test result in the period October 202... Read More about Influence of setting-dependent contacts and protective behaviours on asymptomatic SARS-CoV-2 infection amongst members of a UK university.

Uncertainty and error in SARS-CoV-2 epidemiological parameters inferred from population-level epidemic models (2022)
Journal Article
Whittaker, D. G., Herrera-Reyes, A. D., Hendrix, M., Owen, M. R., Band, L. R., Mirams, G. R., …Preston, S. P. (2023). Uncertainty and error in SARS-CoV-2 epidemiological parameters inferred from population-level epidemic models. Journal of Theoretical Biology, 558, Article 111337. https://doi.org/10.1016/j.jtbi.2022.111337

During the SARS-CoV2 pandemic, epidemic models have been central to policy-making. Public health responses have been shaped by model-based projections and inferences, especially related to the impact of various non-pharmaceutical interventions. Accom... Read More about Uncertainty and error in SARS-CoV-2 epidemiological parameters inferred from population-level epidemic models.

The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout (2022)
Journal Article
Knight, H., Jia, R., Ayling, K., Blake, H., Morling, J. R., Villalon, A. M., …Vedhara, K. (2023). The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout. Perspectives in Public Health, 143(4), 220-224. https://doi.org/10.1177/17579139221094750

Aims: Development and rollout of vaccines offers the best opportunity for population protection against the SARS-CoV-2 (COVID-19) virus. However, hesitancy towards the vaccines might impede successful uptake in the United Kingdom, particularly in you... Read More about The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout.

Relationship between Anxiety, Depression, and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Proof of Concept (2022)
Journal Article
Vedhara, K., Ayling, K., Jia, R., Fairclough, L., Morling, J. R., Ball, J. K., …Tighe, P. (2022). Relationship between Anxiety, Depression, and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Proof of Concept. Journal of Infectious Diseases, 225(12), 2137-2141. https://doi.org/10.1093/infdis/jiac006

Background: Psychological factors can influence susceptibility to viral infections. We examined whether such influences are evident in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Methods: Participants (n=102) completed mea... Read More about Relationship between Anxiety, Depression, and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Proof of Concept.

SARS-CoV-2 infection in UK university students: Lessons from September-December 2020 and modelling insights for future student return (2021)
Journal Article
Enright, J., Hill, E. M., Stage, H. B., Bolton, K. J., Nixon, E. J., Fairbanks, E. L., …Tildesley, M. J. (2021). SARS-CoV-2 infection in UK university students: Lessons from September-December 2020 and modelling insights for future student return. Royal Society Open Science, 8(8), Article 210310. https://doi.org/10.1098/rsos.210310

In this paper, we present work on SARS-CoV-2 transmission in UK higher education settings using multiple approaches to assess the extent of university outbreaks, how much those outbreaks may have led to spillover in the community, and the expected ef... Read More about SARS-CoV-2 infection in UK university students: Lessons from September-December 2020 and modelling insights for future student return.

Prospective examination of mental health in university students during the COVID-19 pandemic (2021)
Working Paper
Jia, R., Knight, H., Ayling, K., Coupland, C., Corner, J., Denning, C., …Vedhara, K. Prospective examination of mental health in university students during the COVID-19 pandemic

Background The impact of changing social restrictions on the mental health of students during the COVID-19 pandemic warrants exploration. Aims To prospectively examine changes to university students’ mental health during the pandemic. Methods S... Read More about Prospective examination of mental health in university students during the COVID-19 pandemic.

Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study (2021)
Journal Article
Blake, H., Knight, H., Jia, R., Corner, J., Morling, J. R., Denning, C., …Vedhara, K. (2021). Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study. International Journal of Environmental Research and Public Health, 18(8), Article 4182. https://doi.org/10.3390/ijerph18084182

We aimed to explore university students’ perceptions and experiences of SARS-CoV-2 mass asymptomatic testing, social distancing and self-isolation, during the COVID-19 pandemic. This qualitative study comprised of four rapid online focus groups condu... Read More about Students’ views towards sars-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the covid-19 pandemic: A qualitative study.

Students’ Views Towards SARS-CoV-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study (2021)
Working Paper
Blake, H., Knight, H., Jia, R., Corner, J., Morling, J. R., Denning, C., …Vedhara, K. Students’ Views Towards SARS-CoV-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study

We aimed to explore university students’ perceptions and experiences of SARS-CoV-2 mass asymptomatic testing, social distancing and self-isolation during the COVID-19 pandemic. This qualitative study comprised of four rapid online focus groups conduc... Read More about Students’ Views Towards SARS-CoV-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study.

Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort (2020)
Working Paper
Jia, R., Knight, H., Blake, H., Corner, J., Denning, C., Ball, J., …Vedhara, K. Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort

Objective: This study examined the COVID-19 risk perceptions and mental health of university students on returning to campus in the midst of the COVID-19 pandemic. Methods: An online survey was completed during the first four weeks of the academic... Read More about Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort.

Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection (2019)
Journal Article
Venkatesan, S., Myles, P. R., Bolton, K. J., Muthuri, S. G., Al Khuwaitir, T., Anovadiya, A. P., …Nguyen-Van-Tam, J. S. (2020). Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection. Journal of Infectious Diseases, 221(3), 356–366. https://doi.org/10.1093/infdis/jiz152

© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. BACKGROUND: The effect of neuraminidase inhibitor (NAI) treatment o... Read More about Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection.

Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control (2015)
Journal Article
Bolton, K. J., McCaw, J. M., Brown, L., Jackson, D., Kedzierska, K., & McVernon, J. (2015). Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control. PLoS ONE, 10(3), https://doi.org/10.1371/journal.pone.0120138

Vaccines that trigger an influenza-specific cytotoxic T cell (CTL) response may aid pandemic control by limiting the transmission of novel influenza A viruses (IAV). We consider interventions with hypothetical CTL-inducing vaccines in a range of epid... Read More about Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control.

The influence of changing host immunity on 1918–19 pandemic dynamics (2014)
Journal Article
Bolton, K., McCaw, J., McVernon, J., & Mathews, J. (2014). The influence of changing host immunity on 1918–19 pandemic dynamics. Epidemics, 8, 18-27. https://doi.org/10.1016/j.epidem.2014.07.004

The sociological and biological factors which gave rise to the three pandemic waves of Spanish influenza in England during 1918–19 are still poorly understood. Symptom reporting data available for a limited set of locations in England indicates that... Read More about The influence of changing host immunity on 1918–19 pandemic dynamics.