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Cryo-scanning electron microscopy demonstrates that ice morphology is not associated with the post-thaw survival of domestic boar (Sus domesticus) spermatozoa: A comparison of directional and conventional freezing methods (2022)
Journal Article
Gillis, J. D., Holt, W. V., Penfold, L. M., Woad, K. J., Graham, J. K., Watts, J. A., …Yon, L. (2022). Cryo-scanning electron microscopy demonstrates that ice morphology is not associated with the post-thaw survival of domestic boar (Sus domesticus) spermatozoa: A comparison of directional and conventional freezing methods. Cryobiology, 108, 10-18. https://doi.org/10.1016/j.cryobiol.2022.08.006

Directional freezing (in 2 or 10 ml hollow glass tubes) has been reported to improve post-thaw sperm survival parameters compared to conventional methods (in 0.5 ml straws). However, the biophysical properties that increase post-thaw survival are poo... Read More about Cryo-scanning electron microscopy demonstrates that ice morphology is not associated with the post-thaw survival of domestic boar (Sus domesticus) spermatozoa: A comparison of directional and conventional freezing methods.

A randomised controlled trial to evaluate the impact of indoor living space on dairy cow production, reproduction and behaviour (2022)
Journal Article
Thompson, J. S., Hudson, C. D., Huxley, J. N., Kaler, J., Robinson, R. S., Woad, K. J., …Green, M. J. (2022). A randomised controlled trial to evaluate the impact of indoor living space on dairy cow production, reproduction and behaviour. Scientific Reports, 12(1), Article 3849. https://doi.org/10.1038/s41598-022-07826-9

As a global society, we have a duty to provide suitable care and conditions for farmed livestock to protect animal welfare and ensure the sustainability of our food supply. The suitability and biological impacts of housing conditions for intensively... Read More about A randomised controlled trial to evaluate the impact of indoor living space on dairy cow production, reproduction and behaviour.

Transforming growth factor-β1 disrupts angiogenesis during the follicular–luteal transition through the Smad–serpin family E member 1 (SERPINE1)/serpin family B member 5 (SERPINB5) signalling pathway in the cow (2021)
Journal Article
Yan, L., Qu, X., Yu, J., Robinson, B., Woad, K., & Shi, Z. (2021). Transforming growth factor-β1 disrupts angiogenesis during the follicular–luteal transition through the Smad–serpin family E member 1 (SERPINE1)/serpin family B member 5 (SERPINB5) signalling pathway in the cow. Reproduction, Fertility and Development, 33(10), 643-654. https://doi.org/10.1071/RD20325

Intense angiogenesis is critical for the development of the corpus luteum and is tightly regulated by numerous factors. However, the exact role transforming growth factor beta 1 (TGFB1) plays during this follicular-luteal transition remains unclear.... Read More about Transforming growth factor-β1 disrupts angiogenesis during the follicular–luteal transition through the Smad–serpin family E member 1 (SERPINE1)/serpin family B member 5 (SERPINB5) signalling pathway in the cow.

Maternal protein restriction affects fetal ovary development in sheep (2021)
Journal Article
Nwachukwu, C. U., Woad, K. J., Barnes, N., Gardner, D. S., & Robinson, R. S. (2021). Maternal protein restriction affects fetal ovary development in sheep. Reproduction and Fertility, 2(2), 161-171. https://doi.org/10.1530/raf-20-0073

Maternal malnutrition has important developmental consequences for the foetus. Indeed, adverse fetal ovarian development could have lifelong impact, with potentially reduced ovarian reserve and fertility of the offspring. This study investigated the... Read More about Maternal protein restriction affects fetal ovary development in sheep.

Detrimental effects of uterine disease and lipopolysaccharide on luteal angiogenesis (2020)
Journal Article
Mohammed, Z. A., Robinson, R. S., Harris, R., McLaughlin, Y., Turnbull, K. E., Mann, G. E., & Woad, K. J. (2020). Detrimental effects of uterine disease and lipopolysaccharide on luteal angiogenesis. Journal of Endocrinology, 245(1), 79-92. https://doi.org/10.1530/JOE-19-0443

© 2020 Society for Endocrinology Reproductive tract inflammatory disease (RTID) commonly occurs after the traumatic events of parturition and adversely affects follicular function. This study is the first to describe the cellular and steroidogenic ch... Read More about Detrimental effects of uterine disease and lipopolysaccharide on luteal angiogenesis.

Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles (2019)
Journal Article
Mohammed, A., Woad, K. J., Mann, G. E., Craigon, J., Raine-Fenning, N., & Robinson, R. S. (2019). Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles. Fertility and Sterility, 112(3), 491-502.e3. https://doi.org/10.1016/j.fertnstert.2019.04.021

© 2019 American Society for Reproductive Medicine Objective: To evaluate the effectiveness of progestogen supplementation in improving clinical pregnancy rates in women undergoing fresh IVF cycles and to compare different routes, start times, duratio... Read More about Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles.

Gene expression profiling of breast tumours from New Zealand patients (2017)
Journal Article
Muthukaruppan, A., Lasham, A., Blenkiron, C., Woad, K. J., Black, M. A., Knowlton, N., …Shelling, A. N. (2017). Gene expression profiling of breast tumours from New Zealand patients. New Zealand Medical Journal, 130(1464), Article 7396

AIMS: New Zealand has one of the highest rates of breast cancer incidence in the world. We investigated the gene expression profiles of breast tumours from New Zealand patients, compared them to gene expression profiles of international breast cancer... Read More about Gene expression profiling of breast tumours from New Zealand patients.

Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors (2016)
Journal Article
Muthukaruppan, A., Lasham, A., Woad, K. J., Black, M. A., Blenkiron, C., Miller, L. D., …Print, C. G. (2017). Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors. Clinical Breast Cancer, 17(2), https://doi.org/10.1016/j.clbc.2016.09.001

Background Molecular markers have transformed our understanding of the heterogeneity of breast cancer and have allowed the identification of genomic profiles of estrogen receptor (ER)-? signaling. However, our understanding of the transcriptional... Read More about Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors.

Luteal angiogenesis and its control (2016)
Journal Article
Woad, K. J., & Robinson, R. S. (2016). Luteal angiogenesis and its control. Theriogenology, 86(1), 221-228. https://doi.org/10.1016/j.theriogenology.2016.04.035

Angiogenesis, the formation of new blood vessels from pre-existing ones, is critical to luteal structure and function; In addition, it is a complex and tightly regulated process. Not only does rapid and extensive angiogenesis occur to provide the cor... Read More about Luteal angiogenesis and its control.