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Insights into the influence of the cooling profile on the reconstitution times of amorphous lyophilized protein formulations (2015)
Journal Article
Beech, K. E., Biddlecombe, J. G., van der Walle, C. F., Stevens, L. A., Rigby, S. P., Burley, J. C., …Allena, S. (2015). Insights into the influence of the cooling profile on the reconstitution times of amorphous lyophilized protein formulations. European Journal of Pharmaceutics and Biopharmaceutics, 96, 247-254. https://doi.org/10.1016/j.ejpb.2015.07.029

Lyophilized protein formulations must be reconstituted back into solution prior to patient administration and in this regard long reconstitution times are not ideal. The factors that govern reconstitution time remain poorly understood. The aim of thi... Read More about Insights into the influence of the cooling profile on the reconstitution times of amorphous lyophilized protein formulations.