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Use of neuraminidase inhibitors for rapid containment of influenza: a systematic review and meta-analysis of individual and household transmission studies (2014)
Journal Article
Okoli, G., Otete, H., Beck, C., & Nguyen-Van-Tam, J. (2014). Use of neuraminidase inhibitors for rapid containment of influenza: a systematic review and meta-analysis of individual and household transmission studies. PLoS ONE, 9(12), doi:10.1371/journal.pone.0113633

Objectives: To assess the effectiveness of neuraminidase inhibitors for use in rapid containment of influenza. Method: We conducted a systematic review and meta-analysis in accordance with the PRISMA statement. Healthcare databases and sources of gr... Read More about Use of neuraminidase inhibitors for rapid containment of influenza: a systematic review and meta-analysis of individual and household transmission studies.

Neuraminidase inhibitors: who, when, where? (2014)
Journal Article
Nguyen-Van-Tam, J. S., Venkatesan, S., Muthuri, S. G., & Myles, P. R. (2015). Neuraminidase inhibitors: who, when, where?. Clinical Microbiology and Infection, 21(3), doi:10.1016/j.cmi.2014.11.020

Although the neuraminidase inhibitors (NIs), oseltamivir and zanamivir were first licensed in 1999, their clinical effectiveness is still hotly debated. Two rigorous systematic reviews and meta-analyses of the data from clinical trials conducted in c... Read More about Neuraminidase inhibitors: who, when, where?.

Cochrane column (2014)
Journal Article
Nguyen-Van-Tam, J. S., & Nicholson, K. G. (2014). Cochrane column. International Journal of Epidemiology, 43(6), doi:10.1093/ije/dyu219

Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis (2014)
Journal Article
Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J. S., & Lim, W. S. (2015). Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis. Journal of Infectious Diseases, 212(2), 183-194. https://doi.org/10.1093/infdis/jiu645

Background: Most studies have reported that corticosteroid therapy adversely influences influenza-related outcomes. Methods: Electronic databases were searched from inception to March 2013 for experimental and observational studies investigating s... Read More about Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis.

A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims (2014)
Journal Article
Wang, M., Barasheed, O., Rashid, H., Booy, R., El Bashir, H., Haworth, E., …Heron, L. (in press). A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims. Journal of Epidemiology and Global Health, 5(2), doi:10.1016/j.jegh.2014.08.002

BACKGROUND: Cost-effective interventions are needed to control the transmission of viral respiratory tract infections (RTIs) in mass gatherings. Facemasks are a promising preventive measure, however, previous studies on the efficacy of facemasks have... Read More about A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims.

Effectiveness of travel restrictions in the rapid containment of human influenza: a systematic review (2014)
Journal Article
Mateus, A., Otete, H. E., Beck, C. R., Dolan, G. P., & Nguyen-Van-Tam, J. S. (in press). Effectiveness of travel restrictions in the rapid containment of human influenza: a systematic review. Bulletin of the World Health Organization, 92(12), doi:10.2471/blt.14.135590

OBJECTIVE: To assess the effectiveness of internal and international travel restrictions in the rapid containment of influenza. METHODS: We conducted a systematic review according to the requirements of the Preferred Reporting Items for Systemati... Read More about Effectiveness of travel restrictions in the rapid containment of human influenza: a systematic review.

Accumulation of human-adapting mutations during circulation of A(H1N1)pdm09 influenza virus in humans in the United Kingdom (2014)
Journal Article
Elderfield, R. A., Watson, S. J., Godlee, A., Adamson, W. E., Thompson, C. I., Dunning, J., …Nguyen-Van-Tam, J. (in press). Accumulation of human-adapting mutations during circulation of A(H1N1)pdm09 influenza virus in humans in the United Kingdom. Journal of Virology, 88(22), doi:10.1128/JVI.01636-14

The influenza pandemic that emerged in 2009 provided an unprecedented opportunity to study adaptation of a virus recently acquired from an animal source during human transmission. In the United Kingdom, the novel virus spread in three temporally dist... Read More about Accumulation of human-adapting mutations during circulation of A(H1N1)pdm09 influenza virus in humans in the United Kingdom.

Influenza vaccination among Australian Hajj pilgrims: uptake, attitudes, and barriers (2014)
Journal Article
Barasheed, O., Rashid, H., Heron, L., Ridda, I., Haworth, E., Nguyen-Van-Tam, J. S., …Booy, R. (2014). Influenza vaccination among Australian Hajj pilgrims: uptake, attitudes, and barriers. Journal of Travel Medicine, 21(6), doi:10.1111/jtm.12146

Background: Hajj is the largest annual mass gathering where the risk of respiratory infection is high. Although the Saudi Arabian authority recommends influenza vaccination for Hajj pilgrims, the uptake is variable. Influenza vaccine uptake data amon... Read More about Influenza vaccination among Australian Hajj pilgrims: uptake, attitudes, and barriers.

Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK (2014)
Journal Article
Nyland, G., McKenzie, B., Myles, P. R., Semple, M., Lim, W., Openshaw, P. J., …Nguyen-Van-Tam, J. (in press). Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK. Epidemiology and Infection, 143(6), https://doi.org/10.1017/S0950268814001873

Data were extracted from the case records of UK patients admitted with laboratory-confirmed influenza A(H1N1)pdm09. White and non-White patients were characterized by age, sex, socioeconomic status, pandemic wave and indicators of pre-morbid health s... Read More about Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK.

The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis (2014)
Journal Article
Convalescent Plasma Study Group, , Mair-Jenkins, J., Saavedra-Campos, M., Baillie, J. K., Cleary, P., Khaw, F., …Nguyen-Van-Tam, J. S. (2015). The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis. Journal of Infectious Diseases, 211(1), 80-90. https://doi.org/10.1093/infdis/jiu396

Background: Administration of convalescent plasma, serum, or hyperimmune immunoglobulin may be of clinical benefit for treatment of severe acute respiratory infections (SARIs) of viral etiology. We conducted a systematic review and exploratory meta-a... Read More about The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis.

Reply: Letter to the editor, Cochrane rearranged (2014)
Journal Article
Beyer, W., McElhaney, J., Smith, D., Monto, A., Nguyen-Van-Tam, J. S., & Osterhaus, A. (2015). Reply: Letter to the editor, Cochrane rearranged. Vaccine, 33(1), doi:10.1016/j.vaccine.2014.05.045

Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data (2014)
Journal Article
Muthuri, S. G., Venkatesan, S., Myles, P. R., Leonardi-Bee, J., Al Khuwaitir, T. S., Al Mamun, A., …Nguyen-Van-Tam, J. (2014). Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data. Lancet Respiratory Medicine, 2(5), doi:10.1016/S2213-2600(14)70041-4

Neuraminidase inhibitors were widely used during the 2009/10 influenza A H1N1 pandemic, but evidence for their effectiveness in reducing mortality is uncertain. We did a meta-analysis of individual participant data to investigate the association betw... Read More about Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.

Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study (2014)
Journal Article
Hayward, A. C., Fragaszy, E. B., Bermingham, A., Wang, L., Copas, A., Edmunds, W. J., …Zambon, M. (in press). Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study. Lancet Respiratory Medicine, 2(6), https://doi.org/10.1016/s2213-2600%2814%2970034-7

BACKGROUND: Assessment of the effect of influenza on populations, including risk of infection, illness if infected, illness severity, and consultation rates, is essential to inform future control and prevention. We aimed to compare the community burd... Read More about Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study.

The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident (2013)
Journal Article
Puleston, R. L., Mallaghan, C. M., Modha, D. E., Hunter, P. R., Nguyen-Van-Tam, J. S., Regan, C. M., …Chalmers, R. M. (2014). The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident. Journal of Water and Health, 12(1), doi:10.2166/wh.2013.097

Background: We report the first identified outbreak of cryptosporidiosis with Cryptosporidium cuniculus following a water quality incident in Northamptonshire, UK. Methods: A standardised, enhanced Cryptosporidium exposure questionnaire was adminis... Read More about The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident.


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