Research Repository

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Antacid therapy for gastroesophageal reflux in preterm infants: a systematic review (2018)
Journal Article
Dermyshi, E., Mackie, C., Kigozi, P., Schoonakker, B., & Dorling, J. (2018). Antacid therapy for gastroesophageal reflux in preterm infants: a systematic review. BMJ Paediatrics Open, 2(1), doi:10.1136/bmjpo-2018-000287. ISSN 2399-9772

Background: Gastro-oesophageal reflux is prevalent in preterm infants. Despite widespread use in clinical practice, there is still much controversy over the efficacy and safety of drug interventions, particularly antacid therapy. Objective: To syste... Read More

Feed thickener for infants up to six months of age with gastro-oesophageal reflux (Review) (2017)
Journal Article
Kwok, T. C., Ojha, S., & Dorling, J. (in press). Feed thickener for infants up to six months of age with gastro-oesophageal reflux (Review). Cochrane Database of Systematic Reviews, doi:10.1002/14651858.CD003211.pub2. ISSN 1469-493X

Background Gastro-oesophageal reflux (GOR) is common in infants, and feed thickeners are often used to manage it in infants as they are simple to use and perceived to be harmless. However, conflicting evidence exists to support the use of feed thick... Read More

Randomised trial of cord clamping and initial stabilisation at very preterm birth (2017)
Journal Article
Duley, L., Dorling, J., Pushpa-Rajah, A., Oddie, S. J., William Yoxall, C., Schoonakker, B., …Fawke, J. A. (2017). Randomised trial of cord clamping and initial stabilisation at very preterm birth. Archives of Disease in Childhood. Fetal and Neonatal Edition, 103(1), F6-F14. doi:10.1136/archdischild-2016-312567

Objectives: For very preterm births, to compare alternative policies for umbilical cord clamping and immediate neonatal care. Design: Parallel group randomised (1:1) trial, using sealed opaque numbered envelopes. Setting: Eight UK tertiary mate... Read More

Fifteen minute consultation: stabilisaton of the high risk newborn infant beside the mother (2017)
Journal Article
Batey, N., Yoxall, B., Fawke, J., Duley, L., & Dorling, J. (2017). Fifteen minute consultation: stabilisaton of the high risk newborn infant beside the mother. Archives of Disease in Childhood, 102, doi:10.1136/archdischild-2016-312276. ISSN 0003-9888

Paediatric and adult resuscitation is often performed with family present. Current guidelines recommend deferred umbilical cord clamping as part of immediate neonatal care, requiring neonatal assessment next to the mother. This paper describes strate... Read More

Cord pilot trial: update to randomised trial protocol (2015)
Journal Article
Bradshaw, L. E., Pushpa-Rajah, A., Dorling, J., Mitchell, E. J., & Duley, L. (2015). Cord pilot trial: update to randomised trial protocol. Trials, 16, 1-3. doi:10.1186/s13063-015-0936-2

Background: The Cord Pilot Trial aimed to assess the feasibility of conducting a large UK randomised trial to compare the effects of alternative polices for timing of cord clamping (immediate within 20 seconds or deferred after at least 2 minutes) fo... Read More

Cord pilot trial - immediate versus deferred cord clamping for very preterm birth (before 32 weeks gestation): study protocol for a randomized controlled trial (2014)
Journal Article
controlled trial. Trials, 15(258), doi:10.1186/1745-6215-15-258. ISSN 1745-6215

Background: Preterm birth is the most important single determinant of adverse outcome in the United Kingdom; one in every 70 babies (1.4%) is born before 32 weeks (very preterm), yet these births account for over half of infant deaths. Deferring cor... Read More

Elective preterm birth for fetal gastroschisis (Review) (2013)
Journal Article
Grant, N. H., Dorling, J., & Thornton, J. (2013). Elective preterm birth for fetal gastroschisis (Review). Cochrane Database of Systematic Reviews, 2013(6), doi:10.1002/14651858.CD009394.pub2. ISSN 1469-493X

Background: Gastroschisis is an uncommon congenital defect of the interior abdominal wall that results in herniation of intestinal loops outside the abdominal cavity. Babies with gastroschisis generally do well, but there remains a mortality rate of... Read More