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Electrophysiological characterisation of central sensitisation in canine spontaneous osteoarthritis (2018)
Journal Article
Hunt, J. R., Goff, M., Jenkins, H., Harris, J., Knowles, T. G., Lascelles, D., …Murrell, J. C. (2018). Electrophysiological characterisation of central sensitisation in canine spontaneous osteoarthritis. PAIN, 159(11), 2318–2330. doi:10.1097/j.pain.0000000000001336

In man, central sensitisation (CS) contributes to the pain of osteoarthritis (OA). Dogs with spontaneous OA may also exhibit CS. Electrophysiological reflex measurements are more objective than behavioural assessments, and can be used to evaluate CS... Read More

Gainfully employing descending controls in acute and chronic pain management (2018)
Journal Article
White, K., Targett, M., & Harris, J. (2018). Gainfully employing descending controls in acute and chronic pain management. Veterinary Journal, 237, doi:10.1016/j.tvjl.2018.05.005. ISSN 1532-2971

Specific primary afferent fibres termed nociceptors are responsible for transmitting nociceptive information. Centrally the axonal terminals of these fibres synapse with secondary projection neurones in the spinal dorsal horn to transmit nociceptive... Read More