Research Repository

See what's under the surface


Neonatal head and torso vibration exposure during inter-hospital transfer (2017)
Journal Article
Blaxter, L., Yeo, M., McNally, D., Crowe, J. A., Henry, C., Hill, S., …Sharkey, D. (in press). Neonatal head and torso vibration exposure during inter-hospital transfer. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, doi:10.1177/0954411916680235. ISSN 0954-4119

Inter-hospital transport of premature infants is increasingly common, given the centralisation of neonatal intensive care. However, it is known to be associated with anomalously increased morbidity, most notably brain injury, and with increased morta... Read More

Anti-confocal assessment of middle ear inflammation (2016)
Journal Article
Jung, D. S., Crowe, J. A., Birchall, J. P., Somekh, M. G., & See, C. W. (2016). Anti-confocal assessment of middle ear inflammation. Biomedical Optics Express, 8(1), doi:10.1364/BOE.8.000230. ISSN 2156-7085

To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The... Read More

Motion limitations of non-contact photoplethysmography due to the optical and topological properties of skin, Phys Meas (2016)
Journal Article
Butler, M., Crowe, J., Hayes-Gill, B., & Rodmell, P. (2016). Motion limitations of non-contact photoplethysmography due to the optical and topological properties of skin, Phys Meas. Physiological Measurement, 37(5), doi:10.1088/0967-3334/37/5/N27

Non-contact photoplethysmography (PPG) provides multiple benefits over in-contact methods, but is not as tolerant to motion due to the lack of mechanical coupling between the subject and sensor. One limitation of non-contact photoplethysmography is... Read More

Motion limitations of non-contact photoplethysmography due to the optical and topological properties of skin (2016)
Journal Article
Butler, M., Crowe, J. A., Hayes-Gill, B. R., & Rodmell, P. I. (2016). Motion limitations of non-contact photoplethysmography due to the optical and topological properties of skin. Physiological Measurement, 37(5), doi:10.1088/0967-3334/37/5/N27. ISSN 0967-3334

Non-contact photoplethysmography (PPG) provides multiple benefits over in-contact methods, but is not as tolerant to motion due to the lack of mechanical coupling between the subject and sensor. One limitation of non-contact photoplethysmography is d... Read More

An automated quasi-continuous capillary refill timing device (2015)
Journal Article
Blaxter, L., Morris, D. E., Crowe, J. A., Henry, C., Hill, S. J., Sharkey, D., …Hayes-Gill, B. R. (in press). An automated quasi-continuous capillary refill timing device. Physiological Measurement, 37(1), doi:10.1088/0967-3334/37/1/83. ISSN 0967-3334

Capillary refill time (CRT) is a simple means of cardiovascular assessment which is widely used in clinical care. Currently, CRT is measured through manual assessment of the time taken for skin tone to return to normal colour following blanching of t... Read More

Anti-confocal versus confocal assessment of the middle ear simulated by Monte Carlo methods (2015)
Journal Article
Jung, D. S., Crowe, J. A., Birchall, J. P., Somekh, M. G., & See, C. W. (2015). Anti-confocal versus confocal assessment of the middle ear simulated by Monte Carlo methods. Biomedical Optics Express, 6(10), 3820-3825. doi:10.1364/BOE.6.003820

The ability to monitor the inflammatory state of the middle ear mucosa would provide clinical utility. To enable spectral measurements on the mucosa whilst rejecting background signal from the eardrum an anti-confocal system is investigated. In contr... Read More

Objective methods for reliable detection of concealed depression (2015)
Journal Article
Solomon, C., Valstar, M. F., Morriss, R. K., & Crowe, J. (2015). Objective methods for reliable detection of concealed depression. Frontiers in ICT, 2, doi:10.3389/fict.2015.00005

Recent research has shown that it is possible to automatically detect clinical depression from audio-visual recordings. Before considering integration in a clinical pathway, a key question that must be asked is whether such systems can be easily fool... Read More

Monte Carlo photon simulation of an anti-confocal system to monitor middle ear inflammation (2015)
Conference Proceeding
Jung, D. S., Birchall, J. P., Crowe, J. A., See, C. W., & Somekh, M. G. (2015). Monte Carlo photon simulation of an anti-confocal system to monitor middle ear inflammation. In Optical Molecular Probes, Imaging and Drug Delivery 2015, Paper# JT3A.41. doi:10.1364/BODA.2015.JT3A.41

Monte Carlo simulations of an anti-confocal system to monitor middle ear inflammation showed that using a stop to reject the scattering plane, the eardrum, rather than a pinhole to select the imaging plane, improved the signal-to-background ratio.

Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients (2014)
Journal Article
Grubb, M., Carpenter, J., Crowe, J. A., Teoh, J., Marlow, N., Ward, C., …Hayes-Gill, B. R. (2014). Forehead reflectance photoplethysmography to monitor heart rate: preliminary results from neonatal patients. Physiological Measurement, 35(5), doi:10.1088/0967-3334/35/5/881. ISSN 0967-3334

Around 5%–10% of newborn babies require some form of resuscitation at birth and heart rate (HR) is the best guide of efficacy. We report the development and first trial of a device that continuously monitors neonatal HR, with a view to deployment in... Read More

Medical device design for adolescent adherence and developmental goals: a case study of a cystic fibrosis physiotherapy device (2014)
Journal Article
Lang, A. R., Martin, J. L., Sharples, S., & Crowe, J. A. (2014). Medical device design for adolescent adherence and developmental goals: a case study of a cystic fibrosis physiotherapy device. Patient Preference and Adherence, 2014(8), doi:10.2147/PPA.S59423. ISSN 1177-889X

Purpose: This study investigates the psychosocial aspects of adolescent medical device use and the impact on adolescent adherence and goals for the transitional years between child and adulthood. Patients and methods: Interviews were carried out w... Read More

A web-based tool for eliciting probability distributions from experts (2013)
Journal Article
Morris, D. E., Oakley, J. E., & Crowe, J. A. (2014). A web-based tool for eliciting probability distributions from experts. Environmental Modelling and Software, 52, doi:10.1016/j.envsoft.2013.10.010. ISSN 1364-8152

We present a web-based probability distribution elicitation tool: The MATCH Uncertainty Elicitation Tool. The Tool is designed to help elicit probability distributions about uncertain model parameters from experts, in situations where suitable data i... Read More

Laser Doppler blood flow imaging using a CMOS imaging sensor with on-chip signal processing (2013)
Journal Article
He, D., Nguyen, H. C., Hayes-Gill, B. R., Zhu, Y., Crowe, J. A., Gill, C., …Morgan, S. P. (2013). Laser Doppler blood flow imaging using a CMOS imaging sensor with on-chip signal processing. Sensors, 13(9), doi:10.3390/s130912632. ISSN 1424-8220

The first fully integrated 2D CMOS imaging sensor with on-chip signal processing for applications in laser Doppler blood flow (LDBF) imaging has been designed and tested. To obtain a space efficient design over 64 × 64 pixels means that standard proc... Read More

User requirements for the development of smartphone self-reporting applications in healthcare (2013)
Conference Proceeding
Craven, M. P., Selvarajah, K., Miles, R., Schnädelbach, H., Massey, A., Vedhara, K., …Crowe, J. (2013). User requirements for the development of smartphone self-reporting applications in healthcare. In Human-Computer Interaction. Applications and Servicesdoi:10.1007/978-3-642-39262-7_5

Two case studies of the development of Smartphone self-reporting mHealth applications are described: a wellness diary for asthma management combined with Bluetooth pulse oximeter and manual peak flow measurements; and a questionnaire for ecological a... Read More

Native Apps versus Web Apps: which is best for healthcare applications? (2013)
Journal Article
Selvarajah, K., Craven, M. P., Massey, A., Crowe, J., Vedhara, K., & Raine-Fenning, N. (2013). Native Apps versus Web Apps: which is best for healthcare applications?. Lecture Notes in Artificial Intelligence, 8005, doi:10.1007/978-3-642-39262-7_22. ISSN 0302-9743

Smartphone applications (Apps) provide a new way to deliver healthcare, illustrated by the fact that healthcare Apps are estimated to make up over 30% of new Apps currently being developed; with this number seemingly set to increase as the benefits b... Read More

Marked variation in newborn resuscitation practice: a national survey in the UK (2012)
Journal Article
Mann, C., Ward, C., Grubb, M., Hayes-Gill, B., Crowe, J., Marlow, N., & Sharkey, D. (2012). Marked variation in newborn resuscitation practice: a national survey in the UK. Resuscitation, 83(5), doi:10.1016/j.resuscitation.2012.01.002. ISSN 0300-9572

Abstract Background Although international newborn resuscitation guidance has been in force for some time, there are no UK data on current newborn resuscitation practices. Objective Establish delivery room (DR) resuscitation practices in the UK... Read More

A user-centred approach to requirements elicitation in medical device development: a case study from an industry perspective (2012)
Journal Article
Martin, J. L., Clarke, D. J., Morgan, S. P., Crowe, J. A., & Murphy, E. (2012). A user-centred approach to requirements elicitation in medical device development: a case study from an industry perspective. Applied Ergonomics, 43(1), doi:10.1016/j.apergo.2011.05.002. ISSN 0003-6870

The healthcare industry is dependent upon the provision of well designed medical devices. To achieve this it is recommended that user-centred design should begin early, and continue throughout device development. This is a challenge, particularly f... Read More

Surgeon opinion on new technologies in orthopaedic surgery (2011)
Journal Article
Craven, M. P., Martin, J. L., & Crowe, J. A. (2011). Surgeon opinion on new technologies in orthopaedic surgery. Journal of Medical Engineering and Technology, 35(3-4), 139-148. doi:10.3109/03091902.2011.554596

Technological advances such as computer navigation systems and robotics, includingsupport systems for minimally invasive surgery, have the potential to revolutionise howorthopaedic surgery is carried out. However uptake has so far been limited. Incre... Read More

Medical Device Development: the challenge for ergonomics (2008)
Journal Article
Martin, J. L., Norris, B. J., Murphy, E., & Crowe, J. A. (2008). Medical Device Development: the challenge for ergonomics. Applied Ergonomics, 39(3), ISSN 0003-6870

High quality, well designed medical devices are necessary to provide safe and effective clinical care for patients as well as to ensure the health and safety of professional and lay device users. Capturing the user requirements of users and incorpor... Read More