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All Outputs (10)

Evaluating a clinical tool (FAMCAT) for identifying familial hypercholesterolaemia in primary care: a retrospective cohort study (2020)
Journal Article
Akyea, R. K., Qureshi, N., Kai, J., de Lusignan, S., Sherlock, J., McGee, C., & Weng, S. (2020). Evaluating a clinical tool (FAMCAT) for identifying familial hypercholesterolaemia in primary care: a retrospective cohort study. BJGP Open, 4(5), 1-10. https://doi.org/10.3399/bjgpopen20X101114

Background: Familial hypercholesterolaemia (FH) is an inherited lipid disorder causing premature heart disease, which is severely underdiagnosed. Improving the identification of people with FH in primary care settings would help to reduce avoidable h... Read More about Evaluating a clinical tool (FAMCAT) for identifying familial hypercholesterolaemia in primary care: a retrospective cohort study.

An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK (2020)
Journal Article
Patel, M., Lee, S., Levell, N., Smart, P., Kai, J., Thomas, K., & Leighton, P. (2020). An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK. BMJ Open, 10, Article e034692. https://doi.org/10.1136/bmjopen-2019-034692

Objectives: To explore health care professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis.

Setting: UK nationwide.

Participants: 20 qualified HCPs, who had a minimum of two years clinical experience as a... Read More about An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK.

Evidence generated from a realist synthesis of trials on educational weight loss interventions in type 2 diabetes mellitus (2020)
Journal Article
Maula, A., Kendrick, D., Kai, J., & Griffiths, F. (2021). Evidence generated from a realist synthesis of trials on educational weight loss interventions in type 2 diabetes mellitus. Diabetic Medicine, 38(1), Article e14394. https://doi.org/10.1111/dme.14394

Background: Obesity and diabetes are major public health problems. Current approaches to weight loss show varying success. Complex community‐based interventions work through several interconnected stages. An individual’s actions in response to an int... Read More about Evidence generated from a realist synthesis of trials on educational weight loss interventions in type 2 diabetes mellitus.

Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models (2020)
Journal Article
Akyea, R. K., Leonardi-Bee, J., Asselbergs, F. W., Patel, R. S., Durrington, P., Wierzbicki, A. S., …Weng, S. F. (2020). Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models. BMJ Open, 10(7), Article e034564. https://doi.org/10.1136/bmjopen-2019-034564

Introduction: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. With advances in early diagnosis and treatment of CVD and increasing life expectancy, more people are surviving initial CVD events. However, models t... Read More about Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models.

Defining Coordinated Care for People with Rare Conditions: A Scoping Review (2020)
Journal Article
Walton, H., Hudson, E., Simpson, A., Ramsay, A. I. G., Kai, J., Morris, S., …Sutcliffe, A. G. (2020). Defining Coordinated Care for People with Rare Conditions: A Scoping Review. International Journal of Integrated Care, 20(2), Article 14. https://doi.org/10.5334/ijic.5464

Introduction: To coordinate care effectively for rare conditions, we need to understand what coordinated care means. This review aimed to define coordinated care and identify components of coordinated care within the context of rare diseases; by draw... Read More about Defining Coordinated Care for People with Rare Conditions: A Scoping Review.

Understanding the influence of parent-clinician communication on antibiotic prescribing for children with respiratory tract infections in primary care: a qualitative observational study using a conversation analysis approach (2019)
Journal Article
Cabral, C., Horwood, J., Symonds, J., Ingram, J., Lucas, P. J., Redmond, N. M., …Barnes, R. K. (2019). Understanding the influence of parent-clinician communication on antibiotic prescribing for children with respiratory tract infections in primary care: a qualitative observational study using a conversation analysis approach. BMC Family Practice, 20(1), Article 102. https://doi.org/10.1186/s12875-019-0993-9

Background: Acute respiratory tract infections (RTI) in children are a common reason for antibiotic prescribing. Clinicians’ prescribing decisions are influenced by perceived parental expectations for antibiotics, however there is evidence that paren... Read More about Understanding the influence of parent-clinician communication on antibiotic prescribing for children with respiratory tract infections in primary care: a qualitative observational study using a conversation analysis approach.

Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study (2019)
Journal Article
Iyen, B., Qureshi, N., Leonardi-Bee, J., Kai, J., Akyea, R. K., Roderick, P., …Weng, S. (2019). Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study. Atherosclerosis, 287, 8-15. https://doi.org/10.1016/j.atherosclerosis.2019.05.017

Background and aims: Familial hypercholesterolaemia (FH) is a known major cause of premature heart disease. However, the risks of atherosclerotic disease in other vascular regions are less known. We determined the risk of major cardiovascular disease... Read More about Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study.

Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease (2019)
Journal Article
Akyea, R., Kai, J., Qureshi, N., Iyen, B., & Weng, S. (2019). Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease. Heart, 105(13), 975-981. https://doi.org/10.1136/heartjnl-2018-314253

Objective:
To assess low-density lipoprotein cholesterol (LDL-C) response in patients after initiation of statins, and future risk of CVD.

Method:
Prospective cohort study of 165,411 primary care patients, from the UK Clinical Practice Research... Read More about Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease.