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All Outputs (6)

A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease (2016)
Journal Article
Thomas, K. S., Batchelor, J. M., Bath-Hextall, F., Chalmers, J., Clarke, T., Crowe, S., …Williams, H. C. (2016). A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease. Programme Grants for Applied Research, 4(18), https://doi.org/10.3310/pgfar04180

Background Skin diseases are very common and can have a large impact on the quality of life of patients and caregivers. This programme addressed four diseases: (1) eczema, (2) vitiligo, (3) squamous cell skin cancer (SCC) and (4) pyoderma gangreno... Read More about A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease.

Patient-Oriented Eczema Measure (POEM), a core instrument to measure symptoms in clinical trials: a Harmonising Outcome Measures for Eczema (HOME) statement (2016)
Journal Article
Spuls, P., Gerbens, L., Simpson, E., Apfelbacher, C., Chalmers, J., Thomas, K., …Schmitt, J. (2017). Patient-Oriented Eczema Measure (POEM), a core instrument to measure symptoms in clinical trials: a Harmonising Outcome Measures for Eczema (HOME) statement. British Journal of Dermatology, 176(4), 979-984. https://doi.org/10.1111/bjd.15179

Background: The Harmonising Outcome Measures for Eczema (HOME) initiative has defined four core outcome domains for a core outcome set (COS) to be measured in all atopic eczema (AE) trials to ensure cross-trial comparison: clinical signs, symptoms, q... Read More about Patient-Oriented Eczema Measure (POEM), a core instrument to measure symptoms in clinical trials: a Harmonising Outcome Measures for Eczema (HOME) statement.

Strategies used for measuring long-term control in atopic dermatitis trials: A systematic review (2016)
Journal Article
Barbarot, S., Rogers, N. K., Abuabara, K., Aubert, H., Chalmers, J., Flohr, C., …Thomas, K. S. (2016). Strategies used for measuring long-term control in atopic dermatitis trials: A systematic review. Journal of The American Academy of Dermatology, 75(5), https://doi.org/10.1016/j.jaad.2016.05.043

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease. There are no standardised methods for capturing long-term control of AD. Objective: To identify how long-term control has been captured in published randomised controlled t... Read More about Strategies used for measuring long-term control in atopic dermatitis trials: A systematic review.

A functional mechanistic study of the effect of emollients on the structure and function of the skin barrier (2016)
Journal Article
Danby, S., Chalmers, J., Brown, K., Williams, H., & Cork, M. (2016). A functional mechanistic study of the effect of emollients on the structure and function of the skin barrier. British Journal of Dermatology, 175(5), 1011-1019. https://doi.org/10.1111/bjd.14684

Background: Preventing relapses of atopic dermatitis (AD) through the regular use of topical products to repair the skin barrier defect is an emerging concept. It is still unclear if some commonly used emollients exert a positive effect on the skin b... Read More about A functional mechanistic study of the effect of emollients on the structure and function of the skin barrier.