All Outputs (8)

A Case Series Exploration of Multi-Regional Expression Heterogeneity in Triple-Negative Breast Cancer Patients (2022)
Journal Article
Xu, Q., Kaur, J., Wylie, D., Mittal, K., Li, H., Kolachina, R., …Aneja, R. (2022). A Case Series Exploration of Multi-Regional Expression Heterogeneity in Triple-Negative Breast Cancer Patients. International Journal of Molecular Sciences, 23(21), Article 13322. https://doi.org/10.3390/ijms232113322

Extensive intratumoral heterogeneity (ITH) is believed to contribute to therapeutic failure and tumor recurrence, as treatment-resistant cell clones can survive and expand. However, little is known about ITH in triple-negative breast cancer (TNBC) be... Read More about A Case Series Exploration of Multi-Regional Expression Heterogeneity in Triple-Negative Breast Cancer Patients.

Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis (2022)
Journal Article
Chattopadhyay, K., Wang, H., Kaur, J., Nalbant, G., Almaqhawi, A. K., Kundakci, B., …Leonardi-Bee, J. (2022). Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Frontiers in Pharmacology, 13, Article 821810. https://doi.org/10.3389/fphar.2022.821810

Introduction: Many Ayurvedic medicines have the potential for managing type 2 diabetes mellitus (T2DM), with previous systematic reviews demonstrating effectiveness and safety for specific Ayurvedic medicines. However, many of the reviews need updati... Read More about Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis.

Selection of eligible participants for screening for lung cancer using primary care data (2021)
Journal Article
O’Dowd, E. L., Ten Haaf, K., Kaur, J., Duffy, S. W., Hamilton, W., Hubbard, R. B., …Baldwin, D. R. (2022). Selection of eligible participants for screening for lung cancer using primary care data. Thorax, 77(9), 882-890. https://doi.org/10.1136/thoraxjnl-2021-217142

Lung cancer screening is effective if offered to people at increased risk of the disease. Currently, direct contact with potential participants is required for evaluating risk. A way to reduce the number of ineligible people contacted might be to app... Read More about Selection of eligible participants for screening for lung cancer using primary care data.

Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials (2021)
Journal Article
Kundakci, B., Kaur, J., Goh, S. L., Hall, M., Doherty, M., Zhang, W., & Abhishek, A. (2022). Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials. PAIN, 163(8), 1432-1445. https://doi.org/10.1097/j.pain.0000000000002500

Fibromyalgia is a highly heterogeneous condition, but the most common symptoms are widespread pain, fatigue, poor sleep, and low mood. Nonpharmacological interventions are recommended as first-line treatment of fibromyalgia. However which interventio... Read More about Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials.

Comparative efficacy and safety of acetaminophen, topical and oral non-steroidal anti-inflammatory drugs for knee osteoarthritis: evidence from a network meta-analysis of randomized controlled trials and real-world data (2021)
Journal Article
Zeng, C., Doherty, M., Persson, M., Yang, Z., Sarmanova, A., Zhang, Y., …Zhang, W. (2021). Comparative efficacy and safety of acetaminophen, topical and oral non-steroidal anti-inflammatory drugs for knee osteoarthritis: evidence from a network meta-analysis of randomized controlled trials and real-world data. Osteoarthritis and Cartilage, 29(9), 1242-1251. https://doi.org/10.1016/j.joca.2021.06.004

Objective: Current global guidelines regarding the first-line analgesics (acetaminophen, topical or oral non-steroidal anti-inflammatory drugs [NSAIDs]) for knee osteoarthritis remain controversial and their comparative risk–benefit profiles have yet... Read More about Comparative efficacy and safety of acetaminophen, topical and oral non-steroidal anti-inflammatory drugs for knee osteoarthritis: evidence from a network meta-analysis of randomized controlled trials and real-world data.

Reliability of detection of ultrasound and MRI features of hand osteoarthritis: a systematic review and meta-analysis (2021)
Journal Article
Obotiba, A. D., Swain, S., Kaur, J., Doherty, M., Zhang, W., & Abhishek, A. (2022). Reliability of detection of ultrasound and MRI features of hand osteoarthritis: a systematic review and meta-analysis. Rheumatology, 61(2), 542-553. https://doi.org/10.1093/rheumatology/keab470

OBJECTIVES: To systematically review the literature on inter- and intra-rater reliability of scoring US and MRI changes in hand OA. METHODS: MEDLINE, EMBASE, CINHAL, Web of Science and AMED were searched from inception to January 2020. Kappa (κ), wei... Read More about Reliability of detection of ultrasound and MRI features of hand osteoarthritis: a systematic review and meta-analysis.

Synovitis and bone marrow lesions associate with symptoms and radiographic progression in hand osteoarthritis: a systematic review and meta-analysis of observational studies (2021)
Journal Article
Obotiba, A. D., Swain, S., Kaur, J., Yaseen, K., Doherty, M., Zhang, W., & Abhishek, A. (2021). Synovitis and bone marrow lesions associate with symptoms and radiographic progression in hand osteoarthritis: a systematic review and meta-analysis of observational studies. Osteoarthritis and Cartilage, 29(7), 946-955. https://doi.org/10.1016/j.joca.2021.03.018

Aims: To systematically review observational studies for the association between features detected on ultrasound (US) and magnetic resonance imaging (MRI) and, symptoms, signs and radiographic progression of hand osteoarthritis (OA). Methods: Medline... Read More about Synovitis and bone marrow lesions associate with symptoms and radiographic progression in hand osteoarthritis: a systematic review and meta-analysis of observational studies.

Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis—a systematic review and meta-analysis of randomized controlled trials and observational studies (2021)
Journal Article
Ayub, S., Kaur, J., Espahbodi, S., Hall, M., Doherty, M., & Zhang, W. (2021). Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis—a systematic review and meta-analysis of randomized controlled trials and observational studies. Rheumatology, 60(4), 1629–1639. https://doi.org/10.1093/rheumatology/keaa808

Objectives To investigate the efficacy and safety of multiple intra-articular corticosteroid (IACS) injections for the treatment of OA. Methods We conducted electronic searches of several databases for randomized controlled trials (RCTs) and obs... Read More about Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis—a systematic review and meta-analysis of randomized controlled trials and observational studies.