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All Outputs (19)

Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study (2023)
Journal Article
ALSumri, H., Szatkowski, L., Gibson, J., Fiaschi, L., & Bains, M. (2023). Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study. International Journal of Fertility & Sterility, 17(2), 107-114. https://doi.org/10.22074/IJFS.2022.550111.1310

Background: To understand the psychosocial experience of infertility among women with polycystic ovarian syndrome in Oman. Materials and Methods: In this qualitative study, semi-structured interviews were conducted with 20 Omani women diagnosed w... Read More about Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study.

Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman (2022)
Journal Article
Alsumri, H., Fiaschi, L., Gibson, J., Bains, M., & Szatkowski, L. (2022). Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman. Journal of Health and Medical Informatics, 13, Article 54

Objectives: To examine the association between PCOS and selected metabolic, pregnancy and neonatal outcomes among pregnant women and their newborns. Methods: Cohort study using electronic hospital records from two tertiary hospitals in Oman. Data wer... Read More about Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman.

Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink (2021)
Journal Article
Peach, E. J., Pearce, F. A., Gibson, J., Andrew J. Cooper, A. J., Chen, L., & Knaggs, R. D. (2021). Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink. American Journal of Epidemiology, 190(7), 1324-1331. https://doi.org/10.1093/aje/kwab042

Self-controlled study designs can be used to assess the association between exposures and acute outcomes while controlling for important confounders. Using routinely collected health data, a self-controlled case series design was used to investigate... Read More about Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink.

Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink (2021)
Journal Article
Peach, E., Pearce, F., Gibson, J., Cooper, A., Chen, L., & Knaggs, R. (2021). Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink. American Journal of Epidemiology, 190(7), 1324-1331. https://doi.org/10.1093/aje/kwab042

Self-controlled study designs can be used to assess the association between exposures and acute outcomes while controlling for important confounders. Using routinely collected health data, a self-controlled case series design was used to investigate... Read More about Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink.

Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study (2020)
Journal Article
Siraj, R., McKeever, T., Gibson, J., Gordon, A., & Bolton, C. (2021). Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study. Respiratory Medicine, 177, Article 106288. https://doi.org/10.1016/j.rmed.2020.106288

Background: Although cognitive impairment and dementia are common comorbidities in patients with chronic obstructive pulmonary disease (COPD), estimates of incidence following a diagnosis of COPD are inconclusive. Objective: To determine the incidenc... Read More about Risk of incident dementia and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD): A large UK population-based study.

Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study (2020)
Journal Article
Tan, S., Szatkowski, L., Moreton, W., Fiaschi, L., McKeever, T., Gibson, J., & Sharkey, D. (2020). Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study. European Respiratory Journal, 56(1), https://doi.org/10.1183/13993003.00202-2020

Background Globally, bronchopulmonary dysplasia (BPD) continues to increase in preterm infants. Recent studies exploring subsequent early childhood respiratory morbidity have been small or focused on hospital admissions. Primary aim Examine early... Read More about Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study.

Epidemiology of bronchiectasis in the UK: Findings from the British lung foundation’s ‘Respiratory health of the nation’ project (2019)
Journal Article
Snell, N., Gibson, J., Jarrold, I., & Quint, J. K. (2019). Epidemiology of bronchiectasis in the UK: Findings from the British lung foundation’s ‘Respiratory health of the nation’ project. Respiratory Medicine, 158, 21-23. https://doi.org/10.1016/j.rmed.2019.09.012

Key findings of this national survey of non-cystic fibrosis bronchiectasis epidemiology were that its prevalence, incidence and mortality have all increased over recent years; we estimate that around 212,000 people are currently living with bronchiec... Read More about Epidemiology of bronchiectasis in the UK: Findings from the British lung foundation’s ‘Respiratory health of the nation’ project.

Assessment of discharge treatment prescribed to women admitted to hospital for hyperemesis gravidarum (2018)
Journal Article
Fiaschi, L., Housley, G., Nelson-Piercy, C., Gibson, J., Raji, A., Deb, S., & Tata, L. (2019). Assessment of discharge treatment prescribed to women admitted to hospital for hyperemesis gravidarum. International Journal of Clinical Practice, 73(1), Article e13261. https://doi.org/10.1111/ijcp.13261

Aims: Prescribing drug treatment for the management of hyperemesis gravidarum (HG), the most severe form of nausea and vomiting in pregnancy, remains controversial. Since most manufacturers do not recommend prescribing antiemetics during pregnancy, l... Read More about Assessment of discharge treatment prescribed to women admitted to hospital for hyperemesis gravidarum.

Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health (2018)
Journal Article
Gibson, J. E., Ander, E. L., Cave, M., Bath-Hextall, F., Musah, A., & Leonardi-Bee, J. (2018). Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health. Population Health Metrics, 16(12), https://doi.org/10.1186/s12963-018-0168-2

Background: Long-term, low-level exposure to toxic elements in soil may be harmful to human health but large longitudinal cohort studies with sufficient follow-up time to study these effects are cost-prohibitive and impractical. Linkage of routinely... Read More about Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health.

Risk of fall in patients with COPD (2018)
Journal Article
Hakamy, A., Bolton, C. E., Gibson, J. E., & McKeever, T. M. (2018). Risk of fall in patients with COPD. Thorax, 73(11), 1079-1080. https://doi.org/10.1136/thoraxjnl-2017-211008

A matched cohort study was conducted to determine the incidence of falls in patients following a diagnosis of COPD using a UK primary care database. 44 400 patients with COPD and 175?545 non-COPD subjects were identified. The incidence rate of fall p... Read More about Risk of fall in patients with COPD.

The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database (2017)
Journal Article
Hakamy, A., McKeever, T. M., Gibson, J. E., & Bolton, C. E. (in press). The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database. npj Primary Care Respiratory Medicine, 27(1), Article 58. https://doi.org/10.1038/s41533-017-0058-2

Pulmonary rehabilitation is recommended for patients with COPD to improve physical function, breathlessness and quality of life. Using The Health Information Network (THIN) primary care database in UK, we compared the demographic and clinical paramet... Read More about The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database.

Adverse maternal and birth outcomes in women admitted to hospital for hyperemesis gravidarum: A population-based cohort study (2017)
Journal Article
Fiaschi, L., Nelson-Piercy, C., Gibson, J. E., Szatkowski, L., & Tata, L. J. (in press). Adverse maternal and birth outcomes in women admitted to hospital for hyperemesis gravidarum: A population-based cohort study. Paediatric and Perinatal Epidemiology, 32(1), https://doi.org/10.1111/ppe.12416

Background: Evidence for risks of adverse maternal and birth outcomes in women with hyperemesis gravidarum (HG) is predominantly from small studies, unknown, or conflicting. Methods: A population-based cohort study using secondary health care reco... Read More about Adverse maternal and birth outcomes in women admitted to hospital for hyperemesis gravidarum: A population-based cohort study.

A supervised adverse drug reaction signalling framework imitating Bradford Hill’s causality considerations (2015)
Journal Article
Reps, J. M., Garibaldi, J. M., Aickelin, U., Gibson, J. E., & Hubbard, R. B. (2015). A supervised adverse drug reaction signalling framework imitating Bradford Hill’s causality considerations. Journal of Biomedical Informatics, 56, https://doi.org/10.1016/j.jbi.2015.06.011

Big longitudinal observational medical data potentially hold a wealth of information and have been recognised as potential sources for gaining new drug safety knowledge. Unfortunately there are many complexities and underlying issues when analysing l... Read More about A supervised adverse drug reaction signalling framework imitating Bradford Hill’s causality considerations.

What characteristics of primary care and patients are associated with early death in patients with lung cancer in the UK? (2014)
Journal Article
O'Dowd, E. L., McKeever, T. M., Baldwin, D. R., Anwar, S., Powell, H. A., Gibson, J. E., …Hubbard, R. B. (2015). What characteristics of primary care and patients are associated with early death in patients with lung cancer in the UK?. Thorax, 70(2), https://doi.org/10.1136/thoraxjnl-2014-205692

Background: The UK has poor lung cancer survival rates and high early mortality, compared to other countries. We aimed to identify factors associated with early death, and features of primary care that might contribute to late diagnosis. Methods: Al... Read More about What characteristics of primary care and patients are associated with early death in patients with lung cancer in the UK?.

First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study (2014)
Journal Article
Ban, L., West, J., Gibson, J. E., Fiaschi, L., Sokal, R., Doyle, P., …Tata, L. J. (2014). First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study. PLoS ONE, 9(6), Article e100996. https://doi.org/10.1371/journal.pone.0100996

BACKGROUND: Despite their widespread use the effects of taking benzodiazepines and non-benzodiazepine hypnotics during pregnancy on the risk of major congenital anomaly (MCA) are uncertain. The objectives were to estimate absolute and relative risks... Read More about First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study.

Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study (2014)
Journal Article
Ban, L., Gibson, J. E., West, J., Fiaschi, L., Sokal, R., Smeeth, L., …Tata, L. J. (in press). Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study. BJOG: An International Journal of Obstetrics and Gynaecology, 121(12), https://doi.org/10.1111/1471-0528.12682

OBJECTIVE: To estimate risks of major congenital anomaly (MCA) among children of mothers prescribed antidepressants during early pregnancy or diagnosed with depression but without antidepressant prescriptions. DESIGN: Population-based cohort study.... Read More about Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study.

Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs (2014)
Journal Article
Reps, J., M. Garibaldi, J., Aickelin, U., Soria, D., E. Gibson, J., & B. Hubbard, R. (2014). Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs. Drug Safety, 37(3), 163-170. https://doi.org/10.1007/s40264-014-0137-z

Background: Children are frequently prescribed medication `o-label', meaning there has not been sucient testing of the medication to determine its safety or eectiveness. The main reason this safety knowledge is lacking is due to ethical restrictions... Read More about Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs.

A Novel Semisupervised Algorithm for Rare Prescription Side Effect Discovery (2013)
Journal Article
Reps, J. M., Garibaldi, J. M., Aickelin, U., Soria, D., Gibson, J. E., & Hubbard, R. B. (2014). A Novel Semisupervised Algorithm for Rare Prescription Side Effect Discovery. IEEE Journal of Biomedical and Health Informatics, 18(2), 537-547. https://doi.org/10.1109/JBHI.2013.2281505

Drugs are frequently prescribed to patients with the aim of improving each patient's medical state, but an unfortunate consequence of most prescription drugs is the occurrence of undesirable side effects. Side effects that occur in more than one in a... Read More about A Novel Semisupervised Algorithm for Rare Prescription Side Effect Discovery.