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An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids (2015)
Journal Article
Amey, J. S., O'Reilly, A. O., Burton, M. J., Puinean, A. M., Mellor, I. R., Duce, I. R., …Davies, T. E. (2015). An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids. FEBS Letters, 589(5), doi:10.1016/j.febslet.2015.01.020. ISSN 0014-5793

We describe the identification in aphids of a unique heterodimeric voltage-gated sodium channel which has an atypical ion selectivity filter and, unusually for insect channels, is highly insensitive to tetrodotoxin. We demonstrate that this channel h... Read More

In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents (2007)
Journal Article
Stepek, G., Lowe, A. E., Buttle, D. J., Duce, I. R., & Behnke, J. M. (2007). In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents. Journal of Helminthology, 81(4), doi:10.1017/S0022149X0786408X. ISSN 0022-149X

Infections with gastrointestinal (GI) nematodes are amongst the most prevalent worldwide, especially in tropical climates. Control of these infections is primarily through treatment with anthelmintic drugs, but the rapid development of resistance to... Read More