Research Repository

See what's under the surface


Bayesian linear size-and-shape regression with applications to face data (2018)
Journal Article
Dryden, I. L., Kim, K., & Le, H. (2018). Bayesian linear size-and-shape regression with applications to face data. Sankhya A, doi:10.1007/s13171-018-0136-8. ISSN 0972-7671

Regression models for size-and-shape analysis are developed, where the model is specified in the Euclidean space of the landmark coordinates. Statistical models in this space (which is known as the top space or ambient space) are often easier for pra... Read More

Peptide refinement using a stochastic search (2018)
Journal Article
Lewis, N. H., Hitchcock, D. B., Dryden, I. L., & Rose, J. R. (in press). Peptide refinement using a stochastic search. Journal of the Royal Statistical Society: Series C, doi:10.1111/rssc.12280. ISSN 0035-9254

Identifying a peptide based on a scan from a mass spectrometer is an important yet highly challenging problem. To identify peptides, we present a Bayesian approach which uses prior information about the average relative abundances of bond cleavages a... Read More

The decomposition of deformation: new metrics to enhance shape analysis in medical imaging (2018)
Journal Article
Varano, V., Piras, P., Gabriele, S., Teresi, L., Nardinocchi, P., Dryden, I. L., …Puddu, P. E. (in press). The decomposition of deformation: new metrics to enhance shape analysis in medical imaging. Medical Image Analysis, 46, doi:10.1016/j.media.2018.02.005. ISSN 1361-8415

In landmarks-based Shape Analysis size is measured, in most cases, with Centroid Size. Changes in shape are decomposed in affine and non affine components. Furthermore the non affine component can be in turn decomposed in a series of local deformatio... Read More

The TPS Direct Transport: a new method for transporting deformations in the Size-and-shape Space (2017)
Journal Article
deformations in the Size-and-shape Space. International Journal of Computer Vision, doi:10.1007/s11263-017-1031-9. ISSN 0920-5691

Modern shape analysis allows the fine comparison of shape changes occurring between different objects. Very often the classic machineries of Generalized Procrustes Analysis and Principal Component Analysis are used in order to contrast the shape chan... Read More

Covariance analysis for temporal data, with applications to DNA modelling (2017)
Journal Article
Dryden, I. L., Hill, B. C., Wang, H., & Laughton, C. A. (2017). Covariance analysis for temporal data, with applications to DNA modelling. Stat, 6(1), (218-230). doi:10.1002/sta4.149. ISSN 2049-1573

We introduce methodology for analysing the mean size-and-shape and covariance matrix of landmark data that are collected over time. Motivated by a study of DNA damage, we study some permutation based tests for investigating significant differences in... Read More

Participatory modelling for stakeholder involvement in the development of flood risk management intervention options (2016)
Journal Article
Maskrey, S. A., Mount, N. J., Thorne, C. R., & Dryden, I. L. (2016). Participatory modelling for stakeholder involvement in the development of flood risk management intervention options. Environmental Modelling and Software, 82, doi:10.1016/j.envsoft.2016.04.027. ISSN 1364-8152

Advancing stakeholder participation beyond consultation offers a range of benefits for local flood risk management, particularly as responsibilities are increasingly devolved to local levels. This paper details the design and implementation of a par... Read More

Regularisation, interpolation and visualisation of diffusion tensor images using non-Euclidean statistics (2015)
Journal Article
Zhou, D., Dryden, I. L., Koloydenko, A. A., Audenaert, K. M., & Bai, L. (2016). Regularisation, interpolation and visualisation of diffusion tensor images using non-Euclidean statistics. Journal of Applied Statistics, 43(5), doi:10.1080/02664763.2015.1080671

Practical statistical analysis of diffusion tensor images is considered, and we focus primarily on methods that use metrics based on Euclidean distances between powers of diffusion tensors. First we describe a family of anisotropy measures based on a... Read More

Size and shape analysis of error-prone shape data (2014)
Journal Article
Du, J., Dryden, I. L., & Huang, X. (2015). Size and shape analysis of error-prone shape data. Journal of the American Statistical Association, 110(509), doi:10.1080/01621459.2014.908779. ISSN 0162-1459

We consider the problem of comparing sizes and shapes of objects when landmark data are prone to measurement error. We show that naive implementation of ordinary Procrustes analysis that ignores measurement error can compromise inference. To account... Read More

Distances and inference for covariance operators (2014)
Journal Article
Pigoli, D., Aston, J. A., Dryden, I. L., & Secchi, P. (2014). Distances and inference for covariance operators. Biometrika, 101(2), doi:10.1093/biomet/asu008. ISSN 0006-3444

A framework is developed for inference concerning the covariance operator of a functional random process, where the covariance operator itself is an object of interest for statistical analysis. Distances for comparing positive-definite covariance mat... Read More

Rank-based model selection for multiple ions quantum tomography (2012)
Journal Article
Guţă, M., Kypraios, T., & Dryden, I. (2012). Rank-based model selection for multiple ions quantum tomography. New Journal of Physics, 14(105002), doi:10.1088/1367-2630/14/10/105002. ISSN 1367-2630

The statistical analysis of measurement data has become a key component of many quantum engineering experiments. As standard full state tomography becomes unfeasible for large dimensional quantum systems, one needs to exploit prior information and th... Read More

A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design (2012)
Journal Article
Higgins, H., Dryden, I. L., & Green, M. J. (2012). A Bayesian elicitation of veterinary beliefs regarding systemic dry cow therapy: variation and importance for clinical trial design. Preventive Veterinary Medicine, 106(2), doi:10.1016/j.prevetmed.2012.01.017. ISSN 0167-5877

The two key aims of this research were: (i) to conduct a probabilistic elicitation to quantify the variation in veterinarians’ beliefs regarding the efficacy of systemic antibiotics when used as an adjunct to intra-mammary dry cow therapy and (ii) to... Read More

Bayesian alignment of continuous molecular shapes using random fields (2008)
Journal Article
Czogiel, I., Dryden, I. L., & Brignell, C. J. Bayesian alignment of continuous molecular shapes using random fields. Manuscript submitted for publication

Statistical methodology is proposed for comparing molecular shapes. In order to account for the continuous nature of molecules, classical shape analysis methods are combined with techniques used for predicting random fields in spatial statistics. Ap... Read More