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Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 (2014)
Journal Article
Wang, H., Liddell, C. A., Coates, M. M., Mooney, M. D., Levitz, C. E., Schumacher, A. E., …Murray, C. J. L. (2014). Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet, 384(9947), 957-979. https://doi.org/10.1016/s0140-6736%2814%2960497-9

Background Remarkable financial and political efforts have been focused on the reduction of child mortality during the past few decades. Timely measurements of levels and trends in under-5 mortality are important to assess progress towards the Mi... Read More about Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.

Prophylactic antibiotics to prevent cellulitis of the leg: economic analysis of the PATCH I & II trials. (2014)
Journal Article

Background Cellulitis (erysipelas) is a recurring and debilitating bacterial infection of the skin and underlying tissue. We assessed the cost-effectiveness of prophylactic antibiotic treatment to prevent the recurrence of cellulitis using low dose... Read More about Prophylactic antibiotics to prevent cellulitis of the leg: economic analysis of the PATCH I & II trials..

Surgical excision versus imiquimod 5% cream for nodular and superficial basal-cell carcinoma (SINS): a multicentre, non-inferiority, randomised controlled trial (2013)
Journal Article
Bath-Hextall, F., Ozolins, M., Armstrong, S. J., Colver, G. B., Perkins, W., Miller, P. S., & Williams, H. C. (2014). Surgical excision versus imiquimod 5% cream for nodular and superficial basal-cell carcinoma (SINS): a multicentre, non-inferiority, randomised controlled trial. Lancet Oncology, 15(1), 96-105. https://doi.org/10.1016/S1470-2045%2813%2970530-8

Background Basal-cell carcinoma is the most common form of skin cancer and its incidence is increasing worldwide. We aimed to assess the effectiveness of imiquimod cream versus surgical excision in patients with low-risk basal-cell carcinoma. Met... Read More about Surgical excision versus imiquimod 5% cream for nodular and superficial basal-cell carcinoma (SINS): a multicentre, non-inferiority, randomised controlled trial.

UK Dermatology Clinical Trials Network’s STOP GAP trial (a multicentre trial of prednisolone versus ciclosporin for pyoderma gangrenosum): protocol for a randomised controlled trial (2012)
Journal Article
Craig, F. F., Thomas, K. S., Mitchell, E. J., Williams, H. C., Norrie, J., Mason, J. M., & Ormerod, A. D. (2012). UK Dermatology Clinical Trials Network’s STOP GAP trial (a multicentre trial of prednisolone versus ciclosporin for pyoderma gangrenosum): protocol for a randomised controlled trial. Trials, 13(1), Article 51. https://doi.org/10.1186/1745-6215-13-51

Established corticosteroid creams should be applied only once daily in patients with atopic eczema (2007)
Journal Article
Williams, H. C. (2007). Established corticosteroid creams should be applied only once daily in patients with atopic eczema. British medical journal, 334,

Atopic eczema affects many adults and up to 20% of children,1 with health costs comparable to diabetes2 and asthma.3 One community survey of 1760 young children in the United Kingdom found that 84% had mild eczema, 14% moderate, and 2% severe eczema.... Read More about Established corticosteroid creams should be applied only once daily in patients with atopic eczema.

Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg (2007)
Journal Article
Thomas, K. S., Cox, N. H., Savelyich, B. S., Shipley, D., Meredith, S., Nunn, A., Williams, H. C., & Reynolds, N. (2007). Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg. Trials, 8(3),

Background: This paper describes the results of a feasibility study for a randomised controlled trial (RCT). Methods: Twenty-nine members of the UK Dermatology Clinical Trials Network (UK DCTN) expressed an interest in recruiting for this study.... Read More about Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg.

How epidemiology has challenged 3 prevailing concepts about atopic dermatitis (2006)
Journal Article
Williams, H., & Flohr, C. (2006). How epidemiology has challenged 3 prevailing concepts about atopic dermatitis. Journal of Allergy and Clinical Immunology, 118,

We challenge 3 prevailing concepts in understanding atopic dermatitis using data from epidemiologic studies. First, we show that although atopy is associated with atopic dermatitis to some degree, its importance is not likely to be a simple causea... Read More about How epidemiology has challenged 3 prevailing concepts about atopic dermatitis.

Atopic Dermatitis (2005)
Journal Article
Williams, H. C. (2005). Atopic Dermatitis

A 10-year-old girl with atopic dermatitis reports itching that has recently become relentless, resulting in sleep loss. Her mother has been reluctant to treat the girl with topical corticosteroids, because she was told that they damage the skin, bu... Read More about Atopic Dermatitis.

How to reply to referees’ comments when submitting manuscripts for publication (2004)
Journal Article
Williams, H. C. (2004). How to reply to referees’ comments when submitting manuscripts for publication. Journal of The American Academy of Dermatology, 51(1),

Background: The publication of articles in peer-reviewed scientific journals is a fairly complex and stepwise process that involves responding to referees’ comments. Little guidance is available in the biomedical literature on how to deal with such c... Read More about How to reply to referees’ comments when submitting manuscripts for publication.

New treatments for atopic dermatitis (2002)
Journal Article
Williams, H. (2002). New treatments for atopic dermatitis. British medical journal, 324,

Atopic dermatitis now affects 15% to 20% of chil­dren in developed countries, and prevalence in cities in developing countries undergoingrapid demographic changes is quickly following suit. [1] Most cases of atopic dermatitis in a given communityare... Read More about New treatments for atopic dermatitis.

Conflicts of interest in dermatology
Journal Article
Williams, H. C., Naldi, L., Paul, C., Vahlquist, A., Schroter, S., & Jobling, R. Conflicts of interest in dermatology. Acta Dermato-Venereologica, 86(6), https://doi.org/10.2340/00015555-0191

Conflicts of interest exist in dermatology when professional judgement concerning a primary interest, such as research validity, may be influenced by a secondary interest, such as financial gain from a for-profit organization. Conflict of interest... Read More about Conflicts of interest in dermatology.