Skip to main content

Research Repository

Advanced Search

All Outputs (4)

Ex vivo assessment of basal cell carcinoma surgical margins in Mohs surgery by autofluorescence‐Raman spectroscopy: A pilot study (2023)
Journal Article
Boitor, R., Varma, S., Sharma, A., Elsheikh, S., Kulkarni, K., Eldib, K., …Notingher, I. (2023). Ex vivo assessment of basal cell carcinoma surgical margins in Mohs surgery by autofluorescence‐Raman spectroscopy: A pilot study. JEADV Clinical Practice, https://doi.org/10.1002/jvc2.336

Background: Autofluorescence (AF)‐Raman spectroscopy is a technology that can detect tumour tissue in surgically excised skin specimens. The technique does not require tissue fixation, staining, labelling or sectioning, and provides quantitative diag... Read More about Ex vivo assessment of basal cell carcinoma surgical margins in Mohs surgery by autofluorescence‐Raman spectroscopy: A pilot study.

Clinical integration of fast Raman spectroscopy for Mohs micrographic surgery of basal cell carcinoma (2021)
Journal Article
Boitor, R., de Wolf, C., Weesie, F., Shipp, D. W., Varma, S., Veitch, D., …Notingher, I. (2021). Clinical integration of fast Raman spectroscopy for Mohs micrographic surgery of basal cell carcinoma. Biomedical Optics Express, 12(4), 2015-2026. https://doi.org/10.1364/boe.417896

We present the first clinical integration of a prototype device based on integrated auto-fluorescence imaging and Raman spectroscopy (Fast Raman device) for intra-operative assessment of surgical margins during Mohs micrographic surgery of basal cell... Read More about Clinical integration of fast Raman spectroscopy for Mohs micrographic surgery of basal cell carcinoma.

Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery (2017)
Journal Article
Boitor, R., Kong, K., Shipp, D., Varma, S., Koloydenko, A., Kusum, K., …Ioan, N. (in press). Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery. Biomedical Optics Express, 8(12), https://doi.org/10.1364/BOE.8.005749

Multimodal spectral histopathology (MSH), an optical technique combining tissue auto-fluorescence (AF) imaging and Raman micro-spectroscopy (RMS), was previously proposed for detection of residual basal cell carcinoma (BCC) at the surface of surgical... Read More about Automated multimodal spectral histopathology for quantitative diagnosis of residual tumour during basal cell carcinoma surgery.

Tissue diagnosis using power-sharing multifocal Raman micro-spectroscopy and auto-fluorescence imaging (2016)
Journal Article
Sinjab, F., Kong, K., Gibson, G., Varma, S., Williams, H. C., Padgett, M., & Notingher, I. (2016). Tissue diagnosis using power-sharing multifocal Raman micro-spectroscopy and auto-fluorescence imaging. Biomedical Optics Express, 7(8), 2993–3006. https://doi.org/10.1364/BOE.7.002993

We describe a multifocal Raman micro-spectroscopy detection method based on a digital micromirror device, which allows for simultaneous “power-sharing” acquisition of Raman spectra from ad hoc sampling points. As the locations of the points can be ra... Read More about Tissue diagnosis using power-sharing multifocal Raman micro-spectroscopy and auto-fluorescence imaging.