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All Outputs (4)

Sexual dimorphism of brown adipose tissue function (2019)
Journal Article
Robinson, L. J., Law, J., Astle, V., Gutiérrez García, M., Ohja, S., Symonds, M. E., …Budge, H. (2019). Sexual dimorphism of brown adipose tissue function. Journal of Pediatrics, 210, 166-172.e1. https://doi.org/10.1016/j.jpeds.2019.03.003

Objective To determine whether brown adipose tissue (BAT) activity in school-age children differs between the sexes and to explore the impact of dietary intake, sedentary behavior, and picky/fussy eating. Study design Children aged 8.5-11.8 year... Read More about Sexual dimorphism of brown adipose tissue function.

Exercise-induced ‘browning’ of adipose tissues (2017)
Journal Article
Aldiss, P., Betts, J. A., Sale, C., Pope, M., Budge, H., & Symonds, M. E. (2018). Exercise-induced ‘browning’ of adipose tissues. Metabolism, 81, https://doi.org/10.1016/j.metabol.2017.11.009

Global rates of obesity continue to rise and are necessarily the consequence of a long-term imbalance between energy intake and energy expenditure. This is the result of an expansion of adipose tissue due to both the hypertrophy of existing adipocyte... Read More about Exercise-induced ‘browning’ of adipose tissues.

Gene pathway development in human epicardial adipose tissue during early life (2016)
Journal Article
Ojha, S., Fainberg, H. P., Wilson, V., Pelella, G., Castellanos, M., May, S., …Budge, H. (in press). Gene pathway development in human epicardial adipose tissue during early life. JCI insight, 1(13), Article e87460. https://doi.org/10.1172/jci.insight.87460

Studies in rodents and newborn humans demonstrate the influence of brown adipose tissue (BAT) in temperature control and energy balance and a critical role in the regulation of body weight. Here, we obtained samples of epicardial adipose tissue (EAT)... Read More about Gene pathway development in human epicardial adipose tissue during early life.

Maternal nutrient restriction during late gestation and early postnatal growth in sheep differentially reset the control of energy metabolism in the gastric mucosa (2011)
Journal Article
Sebert, S., Dellschaft, N., Chan, L., Street, H., Henry, M., Francois, C., …Symonds, M. E. (2011). Maternal nutrient restriction during late gestation and early postnatal growth in sheep differentially reset the control of energy metabolism in the gastric mucosa. Endocrinology, 152(7), https://doi.org/10.1210/en.2011-0169

Fetal growth restriction followed by accelerated postnatal growth contributes to impaired metabolic function in adulthood. The extent to which these outcomes may be mediated centrally within the hypothalamus, as opposed to in the periphery within the... Read More about Maternal nutrient restriction during late gestation and early postnatal growth in sheep differentially reset the control of energy metabolism in the gastric mucosa.