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All Outputs (7)

Thymosin beta 4 prevents systemic lipopolysaccharide-induced plaque load in middle-age APP/PS1 mice (2023)
Journal Article
Othman, O., Marshall, H., Masterson, M., Winlow, P., Gibson, G., Ding, Y., & Pardon, M. (2023). Thymosin beta 4 prevents systemic lipopolysaccharide-induced plaque load in middle-age APP/PS1 mice. International Immunopharmacology, 117, Article 109951. https://doi.org/10.1016/j.intimp.2023.109951

Lipopolysaccharide (LPS) produced by the gut during systemic infections and inflammation is thought to contribute to Alzheimer's disease (AD) progression. Since thymosin beta 4 (Tβ4) effectively reduces LPS-induced inflammation in sepsis, we tested i... Read More about Thymosin beta 4 prevents systemic lipopolysaccharide-induced plaque load in middle-age APP/PS1 mice.

Photoperiodic changes in adiposity increase sensitivity of female Siberian hamsters to systemic VGF derived peptide TLQP-21 (2019)
Journal Article
Lisci, C., Lewis, J. E., Daniel, Z. C., Stevenson, T. J., Monnier, C., Marshall, H. J., …Jethwa, P. H. (2019). Photoperiodic changes in adiposity increase sensitivity of female Siberian hamsters to systemic VGF derived peptide TLQP-21. PLoS ONE, 14(8), Article e0221517. https://doi.org/10.1371/journal.pone.0221517

TLQP-21, a peptide encoded by the highly conserved vgf gene, is expressed in neuroendocrine cells and has been the most prominent VGF-derived peptide studied in relation to control of energy balance. The recent discovery that TLQP-21 is the natural a... Read More about Photoperiodic changes in adiposity increase sensitivity of female Siberian hamsters to systemic VGF derived peptide TLQP-21.

Infusions of scopolamine in dorsal hippocampus reduce anticipatory responding in an appetitive trace conditioning procedure (2018)
Journal Article
Pezze, M., Marshall, H., & Cassaday, H. (2018). Infusions of scopolamine in dorsal hippocampus reduce anticipatory responding in an appetitive trace conditioning procedure. Brain and Behavior, https://doi.org/10.1002/brb3.1147

Trace conditioning is impaired by lesions to dorsal hippocampus, as well as by treatment with the muscarinic acetylcholine antagonist scopolamine. However, the role of muscarinic receptors within hippocampus has received little attention. The present... Read More about Infusions of scopolamine in dorsal hippocampus reduce anticipatory responding in an appetitive trace conditioning procedure.

Role of the anterior cingulate cortex in the retrieval of novel object recognition memory after a long delay (2017)
Journal Article
Pezze, M. A., Marshall, H. J., Fone, K. C., & Cassaday, H. J. (2017). Role of the anterior cingulate cortex in the retrieval of novel object recognition memory after a long delay. Learning and Memory, 24(7), 310-317. https://doi.org/10.1101/lm.044784.116

Previous in vivo electrophysiological studies suggest that the anterior cingulate cortex (ACgx) is an important substrate of novel object recognition (NOR) memory. However, intervention studies are needed to confirm this conclusion and permanent lesi... Read More about Role of the anterior cingulate cortex in the retrieval of novel object recognition memory after a long delay.

Scopolamine impairs appetitive but not aversive trace conditioning: role of the medial prefrontal cortex (2017)
Journal Article
Pezze, M. A., Marshall, H. J., & Cassaday, H. J. (2017). Scopolamine impairs appetitive but not aversive trace conditioning: role of the medial prefrontal cortex. Journal of Neuroscience, 37(26), https://doi.org/10.1523/JNEUROSCI.3308-16.2017

The muscarinic acetylcholine (ACh) receptor is an important modulator of medial prefrontal cortex (mPFC) functions, such as the working memory required to bridge a trace interval in associative leaning. Aversive and appetitive trace conditioning proc... Read More about Scopolamine impairs appetitive but not aversive trace conditioning: role of the medial prefrontal cortex.

The dopamine D1 receptor agonist SKF81297 has dose-related effects on locomotor activity but is without effect in a CER trace conditioning procedure conducted with two versus four trials (2016)
Journal Article
Pezze, M. A., Marshall, H. J., & Cassaday, H. J. (2016). The dopamine D1 receptor agonist SKF81297 has dose-related effects on locomotor activity but is without effect in a CER trace conditioning procedure conducted with two versus four trials. Learning and Motivation, 55, 53-64. https://doi.org/10.1016/j.lmot.2016.06.001

In an appetitively motivated procedure, we have previously reported that systemic treatment with the dopamine (DA) D1 receptor agonist SKF81297 (0.4 and 0.8 mg/kg) depressed acquisition at a 2s inter-stimulus-interval (ISI), suitable to detect trace... Read More about The dopamine D1 receptor agonist SKF81297 has dose-related effects on locomotor activity but is without effect in a CER trace conditioning procedure conducted with two versus four trials.

Dopamine D1 receptor stimulation modulates the formation and retrieval of novel object recognition memory: role of the prelimbic cortex. (2015)
Journal Article
Cassaday, H., Pezze, M., Marshall, H., & Fone, K. (2015). Dopamine D1 receptor stimulation modulates the formation and retrieval of novel object recognition memory: role of the prelimbic cortex. European Neuropsychopharmacology, 25(11), 2145-2156. https://doi.org/10.1016/j.euroneuro.2015.07.018

© 2015 The Authors. Previous studies have shown that dopamine D1 receptor antagonists impair novel object recognition memory but the effects of dopamine D1 receptor stimulation remain to be determined. This study investigated the effects of the selec... Read More about Dopamine D1 receptor stimulation modulates the formation and retrieval of novel object recognition memory: role of the prelimbic cortex..