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All Outputs (16)

Innate immune cell instruction using micron-scale 3D objects of varied architecture and polymer chemistry: The ChemoArchiChip (2023)
Journal Article
Vassey, M., Ma, L., Kämmerling, L., Mbadugha, C., Trindade, G. F., Figueredo, G. P., …Alexander, M. R. (2023). Innate immune cell instruction using micron-scale 3D objects of varied architecture and polymer chemistry: The ChemoArchiChip. Matter, 6(3), 887-906. https://doi.org/10.1016/j.matt.2023.01.002

To design effective immunomodulatory implants, innate immune cell interactions at the surface of biomaterials need to be controlled and understood. The architectural design freedom of two-photon polymerization is used to produce arrays of surface-mou... Read More about Innate immune cell instruction using micron-scale 3D objects of varied architecture and polymer chemistry: The ChemoArchiChip.

Strategies for Integrating Metal Nanoparticles with Two-Photon Polymerization Process: Toward High Resolution Functional Additive Manufacturing (2023)
Journal Article
Im, J., Liu, Y., Hu, Q., Trindade, G. F., Parmenter, C., Fay, M., …Turyanska, L. (2023). Strategies for Integrating Metal Nanoparticles with Two-Photon Polymerization Process: Toward High Resolution Functional Additive Manufacturing. Advanced Functional Materials, 33(39), Article 2211920. https://doi.org/10.1002/adfm.202211920

This study reports the successful fabrication of complex 3D metal nanoparticle–polymer nanocomposites using two-photon polymerization (2PP). Three complementary strategies are detailed: in situ formation of metal nanoparticles (MeNPs) through a singl... Read More about Strategies for Integrating Metal Nanoparticles with Two-Photon Polymerization Process: Toward High Resolution Functional Additive Manufacturing.

Elucidating the molecular landscape of the stratum corneum (2022)
Journal Article
Starr, N. J., Khan, M. H., Edney, M. K., Trindade, G. F., Kern, S., Pirkl, A., …Scurr, D. J. (2022). Elucidating the molecular landscape of the stratum corneum. Proceedings of the National Academy of Sciences, 119(12), Article e2114380119. https://doi.org/10.1073/pnas.2114380119

Characterization of the molecular structure of skin, especially the barrier layer, the stratum corneum, is a key research priority for generating understanding to improve diagnostics, aid pharmaceutical delivery, and prevent environmental damage. Our... Read More about Elucidating the molecular landscape of the stratum corneum.

Correction to “Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers” (2022)
Journal Article
Ruiz-Cantu, L., Trindade, G. F., Taresco, V., Zhou, Z., He, Y., Burroughs, L., …Wildman, R. D. (2022). Correction to “Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers”. ACS Applied Materials and Interfaces, 14(6), 8654. https://doi.org/10.1021/acsami.2c00035

The chemical structure of the drug trandolapril has been corrected in Figure 4c. The conclusions of the work have not been affected by this correction. (Figure present).

The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing (2021)
Journal Article
Hu, Q., Rance, G. A., Trindade, G. F., Pervan, D., Jiang, L., Foerster, A., …Wildman, R. D. (2022). The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing. Additive Manufacturing, 51, Article 102575. https://doi.org/10.1016/j.addma.2021.102575

Two-photon polymerisation (2PP) based additive manufacturing has emerged as a powerful technology to fabricate complex three-dimensional micro- and nanoscale architectures. However, a comprehensive understanding of the effect of printing parameters o... Read More about The influence of printing parameters on multi-material two-photon polymerisation based micro additive manufacturing.

Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers (2021)
Journal Article
Ruiz-Cantu, L., Trindade, G. F., Taresco, V., Zhou, Z., He, Y., Burroughs, L., …Wildman, R. D. (2021). Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers. ACS Applied Materials and Interfaces, 13(33), 38969-38978. https://doi.org/10.1021/acsami.1c07850

Controlling the microstructure of materials by means of phase separation is a versatile tool for optimizing material properties. Phase separation has been exploited to fabricate intricate microstructures in many fields including cell biology, tissue... Read More about Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers.

Modelling the influence of UV curing strategies for optimisation of inkjet based 3D printing (2021)
Journal Article
Zhao, P., He, Y., Trindade, G. F., Baumers, M., Irvine, D., Hague, R., …Wildman Conceptualisation, R. (2021). Modelling the influence of UV curing strategies for optimisation of inkjet based 3D printing. Materials and Design, 208, Article 109889. https://doi.org/10.1016/j.matdes.2021.109889

A predictive model is developed to assist in the design and manufacture of structures by inkjet based 3D printing (IJ3DP)/additive manufacturing. IJ3DP often exploits photopolymerisation to rapidly convert a photoreactive liquid ink into a solid prod... Read More about Modelling the influence of UV curing strategies for optimisation of inkjet based 3D printing.

Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices (2021)
Journal Article
He, Y., Abdi, M., Trindade, G. F., Begines, B., Dubern, J. F., Prina, E., …Wildman, R. D. (2021). Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices. Advanced Science, 8(15), Article 2100249. https://doi.org/10.1002/advs.202100249

As the understanding of disease grows, so does the opportunity for personalization of therapies targeted to the needs of the individual. To bring about a step change in the personalization of medical devices it is shown that multi-material inkjet-bas... Read More about Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices.

Residual polymer stabiliser causes anisotropic electrical conductivity during inkjet printing of metal nanoparticles (2021)
Journal Article
Trindade, G. F., Wang, F., Im, J., He, Y., Balogh, A., Scurr, D., …Roberts, C. J. (2021). Residual polymer stabiliser causes anisotropic electrical conductivity during inkjet printing of metal nanoparticles. Communications Materials, 2(1), Article 47. https://doi.org/10.1038/s43246-021-00151-0

Inkjet printing of metal nanoparticles allows for design flexibility, rapid processing and enables the 3D printing of functional electronic devices through co-deposition of multiple materials. However, the performance of printed devices, especially t... Read More about Residual polymer stabiliser causes anisotropic electrical conductivity during inkjet printing of metal nanoparticles.

Modulating the biological function of protein by tailoring the adsorption orientation on nanoparticles (2020)
Journal Article
Jain, A., Trindade, G. F., Hicks, J. M., Potts, J. C., Rahman, R., J. M. Hague, R., …Rawson, F. J. (2021). Modulating the biological function of protein by tailoring the adsorption orientation on nanoparticles. Journal of Colloid and Interface Science, 587, 150-161. https://doi.org/10.1016/j.jcis.2020.12.025

Protein orientation in nanoparticle-protein conjugates plays a crucial role in binding to cell receptors and ultimately, defines their targeting efficiency. Therefore, understanding fundamental aspects of the role of protein orientation upon adsorpti... Read More about Modulating the biological function of protein by tailoring the adsorption orientation on nanoparticles.

Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling (2020)
Journal Article
Kotowska, A. M., Trindade, G. F., Mendes, P. M., Williams, P. M., Aylott, J. W., Shard, A. G., …Scurr, D. J. (2020). Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling. Nature Communications, 11(1), Article 5832. https://doi.org/10.1038/s41467-020-19445-x

Label-free protein characterization at surfaces is commonly achieved using digestion and/or matrix application prior to mass spectrometry. We report the assignment of undigested proteins at surfaces in situ using secondary ion mass spectrometry (SIMS... Read More about Protein identification by 3D OrbiSIMS to facilitate in situ imaging and depth profiling.

Inter-Flake Quantum Transport of Electrons and Holes in Inkjet-Printed Graphene Devices (2020)
Journal Article
Wang, F., Gosling, J. H., Rance, G. A., Trindade, G. F., Makarovsky, O., Cottam, N. D., …Turyanska, L. (2021). Inter-Flake Quantum Transport of Electrons and Holes in Inkjet-Printed Graphene Devices. Advanced Functional Materials, 31(5), Article 2007478. https://doi.org/10.1002/adfm.202007478

© 2020 The Authors. Advanced Functional Materials published by Wiley-VCH GmbH 2D materials have unique structural and electronic properties with potential for transformative device applications. However, such devices are usually bespoke structures ma... Read More about Inter-Flake Quantum Transport of Electrons and Holes in Inkjet-Printed Graphene Devices.

Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles (2020)
Other
Jain, A., Trindade, G., Hicks, J. M., Potts, J. C., Rahman, R., Hague, R., …Rawson, F. Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles

Protein orientation in nanoparticle-protein conjugates plays a crucial role in binding to cell receptors and ultimately, defines their targeting efficiency. Therefore, understanding fundamental aspects of the role of protein orientation upon adsorpti... Read More about Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles.

A Reactive Prodrug Ink Formulation Strategy for Inkjet 3D Printing of Controlled Release Dosage Forms and Implants (2020)
Journal Article
He, Y., Foralosso, R., Ferraz Trindade, G., Ilchev, A., Cantu, L. R., Clark, E., …Wildman, R. D. (2020). A Reactive Prodrug Ink Formulation Strategy for Inkjet 3D Printing of Controlled Release Dosage Forms and Implants. Advanced Therapeutics, 3(6), Article 1900187. https://doi.org/10.1002/adtp.201900187

We propose a strategy for creating tuneable 3D printed drug delivery devices. 3D printing offers the opportunity for improved compliance and patient treatment outcomes through personalisation, but bottlenecks include finding formulations that provide... Read More about A Reactive Prodrug Ink Formulation Strategy for Inkjet 3D Printing of Controlled Release Dosage Forms and Implants.

The chemical throwing power of lithium-based inhibitors from organic coatings on AA2024-T3 (2019)
Journal Article
Visser, P., Marcoen, K., Trindade, G. F., Abel, M., Watts, J. F., Hauffman, T., …Terryn, H. (2019). The chemical throwing power of lithium-based inhibitors from organic coatings on AA2024-T3. Corrosion Science, 150, 194-206. https://doi.org/10.1016/j.corsci.2019.02.009

Chemical throwing power, being the distance over which an inhibitor is able to protect a defect effectively, is an important parameter for active protective coatings. This study investigates the chemical throwing power of lithium-based leachable corr... Read More about The chemical throwing power of lithium-based inhibitors from organic coatings on AA2024-T3.

Chemical Imaging of Buried Interfaces in Organic-Inorganic Devices Using Focused Ion Beam-Time-of-Flight-Secondary-Ion Mass Spectrometry (2019)
Journal Article
Tiddia, M., Mihara, I., Seah, M. P., Trindade, G. F., Kollmer, F., Roberts, C. J., …Havelund, R. (2019). Chemical Imaging of Buried Interfaces in Organic-Inorganic Devices Using Focused Ion Beam-Time-of-Flight-Secondary-Ion Mass Spectrometry. ACS Applied Materials and Interfaces, 11(4), 4500-4506. https://doi.org/10.1021/acsami.8b15091

Copyright © 2019 American Chemical Society. Organic-inorganic hybrid materials enable the design and fabrication of new materials with enhanced properties. The interface between the organic and inorganic materials is often critical to the device's pe... Read More about Chemical Imaging of Buried Interfaces in Organic-Inorganic Devices Using Focused Ion Beam-Time-of-Flight-Secondary-Ion Mass Spectrometry.