Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
(2015)
Journal Article
Johnstone, R. H., Chang, E. T., Bardenet, R., de Boer, T. P., Gavaghan, D. J., Pathmanathan, P., …Mirams, G. R. (2016). Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?. Journal of Molecular and Cellular Cardiology, 96, 49-62. https://doi.org/10.1016/j.yjmcc.2015.11.018
Cardiac electrophysiology models have been developed for over 50 years, and now include detailed descriptions of individual ion currents and sub-cellular calcium handling. It is commonly accepted that there are many uncertainties in these systems, wi... Read More about Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?.