Skip to main content

Research Repository

Advanced Search

All Outputs (14)

The association between living alone, loneliness and suicide mortality and effect modification by age: A case:control study (2024)
Journal Article
Alothman, D., Lewis, S., Card, T., Tyrrell, E., & Fogarty, A. W. (2024). The association between living alone, loneliness and suicide mortality and effect modification by age: A case:control study. Journal of Affective Disorders, 352, 278-280. https://doi.org/10.1016/j.jad.2024.02.047

Background: Social isolation is a potentially reversible risk factor for suicide. Methods: A matched case control study design was used. The study population was from England and identified from an electronic primary case database with linkage to a s... Read More about The association between living alone, loneliness and suicide mortality and effect modification by age: A case:control study.

Primary care consultation patterns prior to suicide: a nationally representative case-control study. (2024)
Journal Article
Alothman, D., Lewis, S., Fogarty, A. W., Card, T., & Tyrrell, E. (2024). Primary care consultation patterns prior to suicide: a nationally representative case-control study. British Journal of General Practice, https://doi.org/10.3399/bjgp.2023.0509

Consultation with primary health care may provide an opportunity to identify patients at higher suicide risk. To explore primary care consultation patterns in the 5 years before suicide to identify suicide high-risk groups and common reasons for cons... Read More about Primary care consultation patterns prior to suicide: a nationally representative case-control study..

Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England (2023)
Journal Article
Alothman, D., Tyrrell, E., Lewis, S., Card, T., & Fogarty, A. W. (2023). Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England. The Lancet Regional Health Europe, 32, Article 100695. https://doi.org/10.1016/j.lanepe.2023.100695

Background: Analgesics prescriptions may provide a marker for identifying individuals at higher risk of suicide. In particular, awareness of which analgesics are implicated may help clinicians assess and modify risk. Method: A case–control study in E... Read More about Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England.

Comparison of the effectiveness of exclusively facilitated clinical teaching as an alternative to traditional practice-based primary care placements (2023)
Journal Article
Tyrrell, E. G., Knox, R., Saha, R., Berry, K., & Taggar, J. S. (2023). Comparison of the effectiveness of exclusively facilitated clinical teaching as an alternative to traditional practice-based primary care placements. Education for Primary Care, 34(3), 152-160. https://doi.org/10.1080/14739879.2023.2217795

Introduction: COVID-19 presented major challenges to undergraduate GP placement capacity and there was an increased reliance on clinical training using facilitated simulation. The authors present a novel comparison of the effectiveness and cost-effec... Read More about Comparison of the effectiveness of exclusively facilitated clinical teaching as an alternative to traditional practice-based primary care placements.

Cost-effectiveness of England's national 'Safe At Home' scheme for reducing hospital admissions for unintentional injury in children aged under 5 (2022)
Journal Article
Jones, M., Hill, T., Coupland, C., Kendrick, D., Akbari, A., Rodgers, S., …Orton, E. (2022). Cost-effectiveness of England's national 'Safe At Home' scheme for reducing hospital admissions for unintentional injury in children aged under 5. Injury Prevention, https://doi.org/10.1136/ip-2022-044698

Background: Injuries in children aged under 5 years most commonly occur in the home and disproportionately affect those living in the most disadvantaged communities. The 'Safe at Home' (SAH) national home safety equipment scheme, which ran in England... Read More about Cost-effectiveness of England's national 'Safe At Home' scheme for reducing hospital admissions for unintentional injury in children aged under 5.

Risk of Suicide After Dementia Diagnosis (2022)
Journal Article
Alothman, D., Card, T., Lewis, S., Tyrrell, E., Fogarty, A. W., & Marshall, C. R. (2022). Risk of Suicide After Dementia Diagnosis. JAMA Neurology, 79(11), 1148-1154. https://doi.org/10.1001/jamaneurol.2022.3094

Importance: Patients with dementia may be at an increased suicide risk. Identifying groups at greatest risk of suicide would support targeted risk reduction efforts by clinical dementia services. Objectives: To examine the association between a d... Read More about Risk of Suicide After Dementia Diagnosis.

Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England (2022)
Journal Article
Alothman, D., Marshall, C. R., Tyrrell, E., Lewis, S., Card, T., & Fogarty, A. (2022). Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England. Journal of Neurology, 269, 4436–4439. https://doi.org/10.1007/s00415-022-11085-z

Objective: To examine the relative risk of suicide mortality in patients with Huntington’s disease (HD). Methods: A case–control study design was used. We used linked electronic records from primary care, secondary care and Office for National Statis... Read More about Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England.

Ethnicity and suicide risk: A population-based study from England (2021)
Journal Article
Alothman, D., Fogarty, A., Tyrrell, E., Lewis, S., & Card, T. (2022). Ethnicity and suicide risk: A population-based study from England. Journal of Affective Disorders, 298(Part A), 555-557. https://doi.org/10.1016/j.jad.2021.11.044

Using multiple linked electronic health databases, we conducted a large case-control study in England from 2001 through 2019 to examine the association between ethnicity and suicide risk. Asian, Black and Other ethnic groups had a significantly lower... Read More about Ethnicity and suicide risk: A population-based study from England.

Risk and prevention of unintentional injuries in children and young people with attention-deficit/hyperactivity disorder (2021)
Journal Article
Tyrrell, E., & Prasad, V. (2021). Risk and prevention of unintentional injuries in children and young people with attention-deficit/hyperactivity disorder. Paediatrics and Child Health, 31(10), 371-375. https://doi.org/10.1016/j.paed.2021.07.001

Injuries among children and young people are a leading cause of morbidity and mortality in the UK and globally. Attention-deficit/hyperactivity disorder (ADHD) is an important neurodevelopmental disorder which can be present from preschool age but is... Read More about Risk and prevention of unintentional injuries in children and young people with attention-deficit/hyperactivity disorder.

Impact of the national home safety equipment scheme ‘Safe At Home’ on hospital admissions for unintentional injury in children under 5: controlled interrupted time series analysis (2021)
Journal Article
Hill, T., Coupland, C., Kendrick, D., Jones, M., Akbari, A., Rodgers, S., …Orton, E. (2022). Impact of the national home safety equipment scheme ‘Safe At Home’ on hospital admissions for unintentional injury in children under 5: controlled interrupted time series analysis. Journal of Epidemiology and Community Health, 76(1), 53-59. https://doi.org/10.1136/jech-2021-216613

Background: Unintentional home injuries are a leading cause of preventable death in young children. Safety education and equipment provision improve home safety practices, but their impact on injuries is less clear. Between 2009 and 2011 a national h... Read More about Impact of the national home safety equipment scheme ‘Safe At Home’ on hospital admissions for unintentional injury in children under 5: controlled interrupted time series analysis.

Incident Type 2 Diabetes and Risk of Fracture: A Comparative Cohort Analysis Using U.K. Primary Care Records (2020)
Journal Article
Davie, G. S., Pal, K., Orton, E., Tyrrell, E. G., & Petersen, I. (2021). Incident Type 2 Diabetes and Risk of Fracture: A Comparative Cohort Analysis Using U.K. Primary Care Records. Diabetes Care, 44(1), 58-66. https://doi.org/10.2337/dc20-1220

Objective: To estimate risk of fracture in men and women with recent diagnosis of type 2 diabetes compared to individuals without diabetes. Research Design and Methods: In this cohort study we used routinely-collected UK primary care data from Th... Read More about Incident Type 2 Diabetes and Risk of Fracture: A Comparative Cohort Analysis Using U.K. Primary Care Records.

Poisoning substances taken by young people: a population-based cohort study (2018)
Journal Article
Tyrrell, E. G., Kendrick, D., Sayal, K., & Orton, E. (2018). Poisoning substances taken by young people: a population-based cohort study. British Journal of General Practice, 68(675), e703-e710. https://doi.org/10.3399/bjgp18X698897

Background: Globally, poisonings account for most medically-attended self-harm. Recent data on poisoning substances are lacking, but needed to inform self-harm prevention. Aim: To assess poisoning substance patterns and trends among 10-24 year olds... Read More about Poisoning substances taken by young people: a population-based cohort study.

Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study (2016)
Journal Article
Tyrrell, E. G., Orton, E., Sayal, K., Baker, R., & Kendrick, D. (2017). Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study. Journal of Public Health, 39(2), Article e1-e9. https://doi.org/10.1093/pubmed/fdw075

Background Accurate and up to date data on changes in poisoning incidence among young people are lacking. Recent linkage of UK primary care, hospital and mortality data allows these to be quantified to inform service delivery. Methods An open coh... Read More about Differing patterns in intentional and unintentional poisonings among young people in England, 1998-2014: a population based cohort study.

Changes in poisonings among adolescents in the UK between 1992 and 2012: a population based cohort study (2016)
Journal Article
Tyrrell, E. G., Orton, E., & Tata, L. J. (2016). Changes in poisonings among adolescents in the UK between 1992 and 2012: a population based cohort study. Injury Prevention, 22(6), 400-406. https://doi.org/10.1136/injuryprev-2015-041901

Background: Poisonings are a common cause of morbidity and mortality among adolescents. Yet surveillance data indicating current incidence rates (IRs) and time trends are lacking, making policy development and service planning difficult. We utilised... Read More about Changes in poisonings among adolescents in the UK between 1992 and 2012: a population based cohort study.