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Alpha-defensin and the Synovasure lateral flow device for the diagnosis of prosthetic joint infection: a systematic review and meta-analysis (2018)
Journal Article
Marson, B. A., Deshmukh, S. R., Grindlay, D. J. C., & Scammell, B. E. (2018). Alpha-defensin and the Synovasure lateral flow device for the diagnosis of prosthetic joint infection: a systematic review and meta-analysis. Bone and Joint Journal, 100-B(6), 703-711. https://doi.org/10.1302/0301-620x.100b6.bjj-2017-1563.r1

Aims The aim of this review is to evaluate the available literature and to calculate a pooled diagnostic sensitivity and specificity for the different alpha-defensin test systems to diagnose peri-prosthetic infection. Materials and Methods Studi... Read More about Alpha-defensin and the Synovasure lateral flow device for the diagnosis of prosthetic joint infection: a systematic review and meta-analysis.

What's new in atopic eczema? An analysis of systematic reviews published in 2015. Part 2: prevention and treatment (2018)
Journal Article
Lloyd-Lavery, A., Rogers, N. K., Davies, E., Grindlay, D. J. C., & Thomas, K. S. (2018). What's new in atopic eczema? An analysis of systematic reviews published in 2015. Part 2: prevention and treatment. Clinical and Experimental Dermatology, 43(6), 653-658. https://doi.org/10.1111/ced.13554

This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE), providing a succinct guide for clinicians and patients. It provides a summary of key findings from 26 systematic reviews that were published... Read More about What's new in atopic eczema? An analysis of systematic reviews published in 2015. Part 2: prevention and treatment.

What’s new in psoriasis treatment? An analysis of systematic reviews published in 2015 (2018)
Journal Article
Foulkes, A., Ferguson, F., Grindlay, D. J., Williams, H. C., Griffiths, C., & Warren, R. (2018). What’s new in psoriasis treatment? An analysis of systematic reviews published in 2015. Clinical and Experimental Dermatology, 43(7), 759-765. https://doi.org/10.1111/ced.13601

This review provides a summary of key findings from 27 systematic reviews of 51 articles first published or indexed during 2015, focusing on the treatment of psoriasis as well as precision medicine in psoriasis. Evidence supports weight loss interven... Read More about What’s new in psoriasis treatment? An analysis of systematic reviews published in 2015.

Risk of skin cancer in people with vitiligo: a systematic review and meta-analysis (2018)
Journal Article
Ban, L., Labbouz, S., Grindlay, D. J., Batchelor, J. M., & Ratib, S. (2018). Risk of skin cancer in people with vitiligo: a systematic review and meta-analysis. British Journal of Dermatology, 179(4), 971-972. https://doi.org/10.1111/bjd.16703

Vitiligo is a chronic disorder causing skin depigmentation with around 1% global prevalence, affecting people of all ages, skin types and genders.1 Due to the absence of melanin in lesional skin there is a theoretical concern that there might be a hi... Read More about Risk of skin cancer in people with vitiligo: a systematic review and meta-analysis.

Quantitative outcomes of a One Health approach to study global health challenges (2018)
Journal Article
Falzon, L. C., Lechner, I., Chantziaras, I., Collineau, L., Courcoul, A., Filippitzi, M., …Brennan, M. L. (2018). Quantitative outcomes of a One Health approach to study global health challenges. EcoHealth, 15(1), 209-227. https://doi.org/10.1007/s10393-017-1310-5

Having gained momentum in the last decade, the One Health initiative promotes a holistic approach to address complex global health issues. Before recommending its adoption to stakeholders, however, it is paramount to first compile quantitative eviden... Read More about Quantitative outcomes of a One Health approach to study global health challenges.

What's new in atopic eczema? An analysis of systematic reviews published in 2015. Part 1: epidemiology and methodology (2018)
Journal Article
Davies, E., Rogers, N. K., Lloyd-Lavery, A., Grindlay, D. J. C., & Thomas, K. S. (2018). What's new in atopic eczema? An analysis of systematic reviews published in 2015. Part 1: epidemiology and methodology. Clinical and Experimental Dermatology, 43(4), 375-379. doi:10.1111/ced.13377

This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE), providing a succinct guide for clinicians and patients. It provides a summary of key findings from 15 systematic reviews that were published... Read More about What's new in atopic eczema? An analysis of systematic reviews published in 2015. Part 1: epidemiology and methodology.

Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature (2017)
Journal Article
Robinson, N. J., Lyons, E., Grindlay, D., & Brennan, M. L. (in press). Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature. Veterinary Sciences, 4(4), https://doi.org/10.3390/vetsci4040058

Rabbits and guinea pigs are increasingly popular pets in the UK, yet little is known about their common ailments, or how these relate to what appears in the published literature. The aim of this study was to characterise the common conditions of rabb... Read More about Veterinarian nominated common conditions of rabbits and guinea pigs compared with published literature.

Quality of life in people with vitiligo: a systematic review and meta-analysis (2017)
Journal Article
Morrison, B., Burden-Teh, E., Batchelor, J. M., Mead, E., Grindlay, D., & Ratib, S. (2018). Quality of life in people with vitiligo: a systematic review and meta-analysis. British Journal of Dermatology, 177(6), e338-e339. https://doi.org/10.1111/bjd.15933

Vitiligo is cosmetically disfiguring and has profound psychosocial effects due to stigmatization, problems in sexual function, anxiety, self-esteem and difficulty finding employment. Previous studies suggest a reduction in quality of life (QoL) due t... Read More about Quality of life in people with vitiligo: a systematic review and meta-analysis.

A systematic review of diagnostic criteria for psoriasis in adults and children: evidence from studies with a primary aim to develop or validate diagnostic criteria (2017)
Journal Article
Burden-Teh, E., Phillips, R., Thomas, K., Ratib, S., Grindlay, D., & Murphy, R. (2018). A systematic review of diagnostic criteria for psoriasis in adults and children: evidence from studies with a primary aim to develop or validate diagnostic criteria. British Journal of Dermatology, 178(5), 1035-1043. https://doi.org/10.1111/bjd.16104

Background: The diagnosis of psoriasis in adults and children is made clinically, for both patient management and the selection of participants in research. Diagnostic criteria provide a structure for clinical assessment, which in turn helps standard... Read More about A systematic review of diagnostic criteria for psoriasis in adults and children: evidence from studies with a primary aim to develop or validate diagnostic criteria.

The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis (2017)
Journal Article
Osinubi, O., Grainge, M. J., Ahmed, A., Batchelor, J. M., Grindlay, D., Thompson, A., & Ratib, S. (2018). The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis. British Journal of Dermatology, 178(4), 863-878. https://doi.org/10.1111/bjd.16049

Background: Vitiligo is a chronic disorder causing skin depigmentation with global prevalence varying from 0.2 to 1.8%. UK guidelines recommend assessment of psychological state during clinical evaluation of vitiligo. However, the prevalence of psych... Read More about The prevalence of psychological comorbidity in people with vitiligo: a systematic review and meta-analysis.

Sample size and number of outcome measures of veterinary randomised controlled trials of pharmaceutical interventions funded by different sources, a cross-sectional study (2017)
Journal Article
Wareham, K., Hyde, R., Grindlay, D. J., Brennan, M. L., & Dean, R. S. (2017). Sample size and number of outcome measures of veterinary randomised controlled trials of pharmaceutical interventions funded by different sources, a cross-sectional study. BMC Veterinary Research, 13, Article 295. https://doi.org/10.1186/s12917-017-1207-0

Background Randomised controlled trials (RCTs) are a key component of the veterinary evidence base. Sample sizes and defined outcome measures are crucial components of RCTs. To describe the sample size and number of outcome measures of veterinary... Read More about Sample size and number of outcome measures of veterinary randomised controlled trials of pharmaceutical interventions funded by different sources, a cross-sectional study.

Sponsorship bias and quality of randomised controlled trials in veterinary medicine (2017)
Journal Article
Wareham, K., Hyde, R., Grindlay, D. J., Brennan, M. L., & Dean, R. S. (in press). Sponsorship bias and quality of randomised controlled trials in veterinary medicine. BMC Veterinary Research, 13(234), https://doi.org/10.1186/s12917-017-1146-9

Background: Randomised controlled trials (RCTs) are considered the gold standard form of evidence for assessing treatment efficacy, but many factors can influence their reliability including methodological quality, reporting quality and funding sourc... Read More about Sponsorship bias and quality of randomised controlled trials in veterinary medicine.

A systematic review of Vancouver B2 and B3 periprosthetic femoral fractures (2017)
Journal Article
Khan, T., Grindlay, D. J., Scammell, B. E., Ollivere, B., Manktelow, A., & Pearson, R. G. (2017). A systematic review of Vancouver B2 and B3 periprosthetic femoral fractures. Bone and Joint Journal, 99-B(4_Supple_B), 17-25. https://doi.org/10.1302/0301-620X.99B4.BJJ-2016-1311.R1

Aims The aim of this study was to investigate the outcomes of Vancouver type B2 and B3 fractures by performing a systematic review of the methods of surgical treatment which have been reported. Materials and Methods A systematic search was perform... Read More about A systematic review of Vancouver B2 and B3 periprosthetic femoral fractures.

Searching the veterinary literature: a comparison of the coverage of veterinary journals by nine bibliographic databases (2016)
Journal Article
Grindlay, D. J., Brennan, M. L., & Dean, R. S. (in press). Searching the veterinary literature: a comparison of the coverage of veterinary journals by nine bibliographic databases. Journal of Veterinary Medical Education, 39(4), https://doi.org/10.3138/jvme.1111.109R

A thorough search of the literature to find the best evidence is central to the practice of evidence-based veterinary medicine. This requires knowing which databases to search to maximize journal coverage. The aim of the present study was to compare... Read More about Searching the veterinary literature: a comparison of the coverage of veterinary journals by nine bibliographic databases.

What's new in atopic eczema? An analysis of systematic reviews published in 2014. Part 2. Treatment and prevention (2016)
Journal Article
Lloyd-Lavery, A., Rogers, N. K., Hatfield, S. J., Grindlay, D., Barnett, R., & Thomas, K. S. (2017). What's new in atopic eczema? An analysis of systematic reviews published in 2014. Part 2. Treatment and prevention. Clinical and Experimental Dermatology, 42(1), 3-7. https://doi.org/10.1111/ced.12967

This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE). It provides a summary of key findings from 12 systematic reviews (SRs) that were published or indexed during 2014, and focuses on the treatm... Read More about What's new in atopic eczema? An analysis of systematic reviews published in 2014. Part 2. Treatment and prevention.

What's new in atopic eczema? An analysis of systematic reviews published in 2014. Part 1. Epidemiology, risk factors and outcomes (2016)
Journal Article
Hatfield, S. J., Rogers, N. K., Lloyd-Lavery, A., Grindlay, D., Barnett, R., & Thomas, K. S. (2016). What's new in atopic eczema? An analysis of systematic reviews published in 2014. Part 1. Epidemiology, risk factors and outcomes. Clinical and Experimental Dermatology, 41(8), 843-846. https://doi.org/10.1111/ced.12977

This review summarizes key findings from nine systematic reviews on atopic eczema (AE) published or first indexed in 2014. It focuses on epidemiology, disease processes and methodological issues. There is reasonable evidence to conclude that high bir... Read More about What's new in atopic eczema? An analysis of systematic reviews published in 2014. Part 1. Epidemiology, risk factors and outcomes.

A systematic review of the literature relating to captive great ape morbidity and mortality (2016)
Journal Article
Strong, V. J., Grindlay, D. J., Redrobe, S., Cobb, M., & White, K. (2016). A systematic review of the literature relating to captive great ape morbidity and mortality. Journal of Zoo and Wildlife Medicine, 47(3), https://doi.org/10.1638/2015-0240.1

Wild bonobos (Pan paniscus), chimpanzees (Pan troglodytes), Western gorillas (Gorilla gorilla), and orangutans (Pongo pygmaeus, Pongo abelii) are threatened with extinction. In order to help maintain a self-sustaining zoo population, clinicians requi... Read More about A systematic review of the literature relating to captive great ape morbidity and mortality.

The epidemiology of childhood psoriasis: a scoping review (2016)
Journal Article
Burden-Teh, E., Thomas, K. S., Ratib, S., Grindlay, D. J., Adaji, E., & Murphy, R. (2016). The epidemiology of childhood psoriasis: a scoping review. British Journal of Dermatology, 174(6), 1242-1257. https://doi.org/10.1111/bjd.14507

Psoriasis is an inflammatory noncommunicable skin disease that affects both adults and children. At present, the epidemiology and natural history of psoriasis are not widely understood. This scoping review aimed to map the existing literature on the... Read More about The epidemiology of childhood psoriasis: a scoping review.