All Outputs (3)

Deuterium brain imaging at 7T during D2O dosing (2022)
Journal Article
Cocking, D., Damion, R. A., Franks, H., Jaconelli, M., Wilkinson, D., Brook, M., …Bowtell, R. (2023). Deuterium brain imaging at 7T during D2O dosing. Magnetic Resonance in Medicine, 89(4), 1514-1521. https://doi.org/10.1002/mrm.29539

Purpose To characterize the (2H) deuterium MR signal measured from human brain at 7T in participants loading with D2O to ˜1.5% enrichment over a six-week period. Methods 2H spectroscopy and imaging measurements were used to track the time-course... Read More about Deuterium brain imaging at 7T during D2O dosing.

5-Carboxylcytosine levels are elevated in human breast cancers and gliomas (2015)
Journal Article
Eleftheriou, M., Jimenez Pascual, A., Wheldon, L., Perry, C., Abakir, A., Arora, A., …Ruzov, A. (2015). 5-Carboxylcytosine levels are elevated in human breast cancers and gliomas. Clinical Epigenetics, 7, 1-6. https://doi.org/10.1186/s13148-015-0117-x

Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era (2014)
Journal Article
Perry, C., Agarwal, D., Abdel-Fatah, T. M., Lourdusamy, A., Grundy, R., Auer, D. T., …Madhusudan, S. (2014). Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era. Oncotarget, 5(14), 5764-5781. https://doi.org/10.18632/oncotarget.2180

Deregulation of multiple DNA repair pathways may contribute to aggressive biology and therapy resistance in gliomas. We evaluated transcript levels of 157 genes involved in DNA repair in an adult glioblastoma Test set (n=191) and validated in ‘The Ca... Read More about Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era.