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All Outputs (4)

Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules (2020)
Journal Article
Delcassian, D., Luzhansky, I., Spanoudaki, V., Bochenek, M., McGladrigan, C., Nguyen, A., …Anderson, D. G. (2020). Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules. Advanced Materials, 32(16), Article 1904502. https://doi.org/10.1002/adma.201904502

© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Encapsulated beta cell transplantation offers a potential cure for a subset of diabetic patients. Once transplanted, beta cell grafts can help to restore glycemic control; however, locating and retr... Read More about Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules.

Improved delivery of PLGA microparticles and microparticle-cell scaffolds in clinical needle gauges using modified viscosity formulations (2018)
Journal Article
Qutachi, O., Wright, E. J., Bray, G., Hamid, O. A., Rose, F. R., Shakesheff, K., & Delcassian, D. (2018). Improved delivery of PLGA microparticles and microparticle-cell scaffolds in clinical needle gauges using modified viscosity formulations. International Journal of Pharmaceutics, 546(1-2), 272-278. https://doi.org/10.1016/j.ijpharm.2018.05.025

Polymer microparticles are widely used as acellular drug delivery platforms in regenerative medicine, and have emerging potential as cellular scaffolds for therapeutic cell delivery. In the clinic, PLGA microparticles are typically administered intra... Read More about Improved delivery of PLGA microparticles and microparticle-cell scaffolds in clinical needle gauges using modified viscosity formulations.

Drug delivery across length scales (2018)
Journal Article
Delcassian, D., Patel, A. K., Cortinas, A. B., & Langer, R. (2019). Drug delivery across length scales. Journal of Drug Targeting, 27(3), 229-243. https://doi.org/10.1080/1061186X.2018.1438440

Over the last century, there has been a dramatic change in the nature of therapeutic, biologically active molecules available to treat disease. Therapies have evolved from extracted natural products towards rationally designed biomolecules, including... Read More about Drug delivery across length scales.

T cell immunoengineering with advanced biomaterials (2017)
Journal Article
Delcassian, D., Sattler, S., & Dunlop, I. E. (2017). T cell immunoengineering with advanced biomaterials. Integrative Biology, 9(3), https://doi.org/10.1039/c6ib00233a

Recent advances in biomaterials design offer the potential to actively control immune cell activation and behaviour. Many human diseases, such as infections, cancer, and autoimmune disorders, are partly mediated by inappropriate or insufficient activ... Read More about T cell immunoengineering with advanced biomaterials.