Research Repository

See what's under the surface


Gap-induced inhibition of the post-auricular muscle response in humans and guinea pigs (2019)
Journal Article
Wilson, C. A., Berger, J. I., de Boer, J., Sereda, M., Palmer, A. R., Hall, D. A., & Wallace, M. N. (2019). Gap-induced inhibition of the post-auricular muscle response in humans and guinea pigs. Hearing Research, 374, 13-23. doi:10.1016/j.heares.2019.01.009

A common method for measuring changes in temporal processing sensitivity in both humans and animals makes use of GaP-induced Inhibition of the Acoustic Startle (GPIAS). It is also the basis of a common method for detecting tinnitus in rodents. Howeve... Read More

Betahistine for tinnitus (Review) (2018)
Journal Article
Wegner, I., Hall, D. A., Smit, A. L., McFerran, D., & Stegeman, I. (2018). Betahistine for tinnitus (Review). Cochrane Database of Systematic Reviews, 2018(12), doi:10.1002/14651858.CD013093.pub2

Background: Tinnitus is a symptom defined as the perception of sound in the absence of an external source. In England alone there are an estimated ¾ million general practice consultations every year where the primary complaint is tinnitus, equating t... Read More

Sound therapy (using amplification devices and/or sound generators) for tinnitus (2018)
Journal Article
Sereda, M., Xia, J., El Refaie, A., Hall, D. A., & Hoare, D. J. (2018). Sound therapy (using amplification devices and/or sound generators) for tinnitus. Cochrane Database of Systematic Reviews, 2018(12), doi:10.1002/14651858.CD013094.pub2

BACKGROUND: Tinnitus affects 10% to 15% of the adult population, with about 20% of these experiencing symptoms that negatively affect quality of life. In England alone there are an estimated ¾ million general practice consultations every year where t... Read More

Pathophysiology of subjective tinnitus: triggers and maintenance (2018)
Journal Article
Haider, H. F., Bojić, T., Ribeiro, S. F., Paço, J., Hall, D., & Szczepek, A. J. (2018). Pathophysiology of subjective tinnitus: triggers and maintenance. Frontiers in Neuroscience, doi:10.3389/fnins.2018.00866

Tinnitus is the conscious perception of a sound without a corresponding external acoustic stimulus, usually described as a phantom perception. One of the major challenges for tinnitus research is to understand the pathophysiological mechanisms trigge... Read More

The Noise Exposure Structured Interview (NESI): an instrument for the comprehensive estimation of lifetime noise exposure (2018)
Journal Article
Guest, H., Dewey, R. S., Plack, C. J., Couth, S., Prendergast, G., Bakay, W., & Hall, D. A. (2018). The Noise Exposure Structured Interview (NESI): an instrument for the comprehensive estimation of lifetime noise exposure. Trends in Hearing, 22, 1-10. doi:10.1177/2331216518803213

Lifetime noise exposure is generally quantified by self report. The accuracy of retrospective self report is limited by respondent recall, but is also bound to be influenced by reporting procedures. Such procedures are of variable quality in current... Read More

Betahistine for tinnitus (Protocol) (2018)
Journal Article
Hall, D. A., Wegner, . I., Smit, A. L., McFerran, D., & Stegeman, I. (2018). Betahistine for tinnitus (Protocol). Cochrane Database of Systematic Reviews, 2018(8), doi:10.1002/14651858.CD013093

Background: Tinnitus describes 'ringing', 'whooshing' or 'hissing' sounds that are heard in the absence of any corresponding external sound. Between 5% and 43% of people experience this symptom and for some it has a significant negative impact on the... Read More

The physiological bases of hidden noise-induced hearing loss: protocol for a functional neuroimaging study (2018)
Journal Article
Dewey, R. S., Hall, D. A., Guest, H., Prendergast, G., Plack, C. J., & Francis, S. T. (2018). The physiological bases of hidden noise-induced hearing loss: protocol for a functional neuroimaging study. JMIR, 7(3), doi:10.2196/resprot.9095. ISSN 1438-8871

Background: Rodent studies indicate that noise exposure can cause permanent damage to synapses between inner hair cells and high-threshold auditory nerve fibers, without permanently altering threshold sensitivity. These demonstrations of what is comm... Read More

Interpreting the Tinnitus Questionnaire (German version):what individual differences are clinically important? (2018)
Journal Article
Hall, D. A., Mehta, R., & Argstatter, H. (2018). Interpreting the Tinnitus Questionnaire (German version):what individual differences are clinically important?. International Journal of Audiology, 57(7), (553-557). doi:10.1080/14992027.2018.1442591. ISSN 1499-2027

Objective: Reporting of clinical significance is recommended because findings can be statistically significant without being relevant to patients. For aiding clinical interpretation of the Tinnitus Questionnaire (TQ), many investigators use a 5-point... Read More

Performance of the Tinnitus Functional Index as a diagnostic instrument in a UK clinical population (2017)
Journal Article
Fackrell, K., Hall, D. A., Barry, J. G., & Hoare, D. J. (2018). Performance of the Tinnitus Functional Index as a diagnostic instrument in a UK clinical population. Hearing Research, 358, doi:10.1016/j.heares.2017.10.016. ISSN 0378-5955

Objectives: The Tinnitus Functional Index (TFI) has been optimised as a diagnostic tool for quantifying the functional impact of tinnitus in US veteran and civilian groups. However, the TFI has not been evaluated for use in other English-speaking cl... Read More

Designing clinical trials for assessing the effectiveness of interventions for tinnitus (2017)
Journal Article
Hall, D. A. (2017). Designing clinical trials for assessing the effectiveness of interventions for tinnitus. Trends in Hearing, 21, doi:10.1177/2331216517736689. ISSN 2331-2165

In the face of finite resources, allocations of research and healthcare funding are dependent upon high-quality evidence. Historically, tinnitus has been the poor cousin of hearing science, with low-quality clinical research providing unreliable esti... Read More

Effects of noise exposure on young adults with normal audiograms II: Behavioral measures (2017)
Journal Article
Prendergast, G., Millman, R. E., Guest, H., Munro, K. J., Kluk, K., Dewey, R. S., …Plack, C. J. (2017). Effects of noise exposure on young adults with normal audiograms II: Behavioral measures. Hearing Research, 356, doi:10.1016/j.heares.2017.10.007. ISSN 0378-5955

An estimate of lifetime noise exposure was used as the primary predictor of performance on a range of behavioral tasks: frequency and intensity difference limens, amplitude modulation detection, interaural phase discrimination, the digit triplet spee... Read More