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All Outputs (17)

Betahistine for tinnitus (Review) (2018)
Journal Article
Wegner, I., Hall, D. A., Smit, A. L., McFerran, D., & Stegeman, I. (2018). Betahistine for tinnitus (Review). Cochrane Database of Systematic Reviews, 2018(12), Article CD013093. https://doi.org/10.1002/14651858.CD013093.pub2

Background: Tinnitus is a symptom defined as the perception of sound in the absence of an external source. In England alone there are an estimated ¾ million general practice consultations every year where the primary complaint is tinnitus, equating t... Read More about Betahistine for tinnitus (Review).

Sound therapy (using amplification devices and/or sound generators) for tinnitus (2018)
Journal Article
Sereda, M., Xia, J., El Refaie, A., Hall, D. A., & Hoare, D. J. (2018). Sound therapy (using amplification devices and/or sound generators) for tinnitus. Cochrane Database of Systematic Reviews, 2018(12), https://doi.org/10.1002/14651858.CD013094.pub2

BACKGROUND: Tinnitus affects 10% to 15% of the adult population, with about 20% of these experiencing symptoms that negatively affect quality of life. In England alone there are an estimated ¾ million general practice consultations every year where t... Read More about Sound therapy (using amplification devices and/or sound generators) for tinnitus.

The COMiT'ID study: developing core outcome domains sets for clinical trials of sound-, psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults (2018)
Journal Article
Hall, D. A., Smith, H., Hibbert, A., Colley, V., Haider, H. F., Horobin, A. J., …Core Outcome Measures in Tinnitus (COMiT). (2018). The COMiT'ID study: developing core outcome domains sets for clinical trials of sound-, psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults. Trends in Hearing, 22, 1-16. https://doi.org/10.1177/2331216518814384

Subjective tinnitus is a chronic heterogeneous condition that is typically managed using intervention approaches based on sound devices, psychologically informed therapies, or pharmaceutical products. For clinical trials, there are currently no commo... Read More about The COMiT'ID study: developing core outcome domains sets for clinical trials of sound-, psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults.

Pathophysiology of subjective tinnitus: triggers and maintenance (2018)
Journal Article
Haider, H. F., Bojić, T., Ribeiro, S. F., Paço, J., Hall, D., & Szczepek, A. J. (2018). Pathophysiology of subjective tinnitus: triggers and maintenance. Frontiers in Neuroscience, 12, Article 866. https://doi.org/10.3389/fnins.2018.00866

Tinnitus is the conscious perception of a sound without a corresponding external acoustic stimulus, usually described as a phantom perception. One of the major challenges for tinnitus research is to understand the pathophysiological mechanisms trigge... Read More about Pathophysiology of subjective tinnitus: triggers and maintenance.

The Noise Exposure Structured Interview (NESI): an instrument for the comprehensive estimation of lifetime noise exposure (2018)
Journal Article
Guest, H., Dewey, R. S., Plack, C. J., Couth, S., Prendergast, G., Bakay, W., & Hall, D. A. (2018). The Noise Exposure Structured Interview (NESI): an instrument for the comprehensive estimation of lifetime noise exposure. Trends in Hearing, 22, 1-10. https://doi.org/10.1177/2331216518803213

Lifetime noise exposure is generally quantified by self report. The accuracy of retrospective self report is limited by respondent recall, but is also bound to be influenced by reporting procedures. Such procedures are of variable quality in current... Read More about The Noise Exposure Structured Interview (NESI): an instrument for the comprehensive estimation of lifetime noise exposure.

Vestibulotoxicity associated with platinum-based chemotherapy in survivors of cancer: a scoping review (2018)
Journal Article
Prayuenyong, P., Taylor, J. A., Pearson, S. E., Gomez, R., Patel, P. M., Hall, D. A., …Baguley, D. M. (2018). Vestibulotoxicity associated with platinum-based chemotherapy in survivors of cancer: a scoping review. Frontiers in Oncology, 8, Article 363. https://doi.org/10.3389/fonc.2018.00363

Background: Cochleotoxicity following the treatment with platinum-based chemotherapy is well documented. The potential for vestibulotoxicity is still unclear. This scoping review examined the extent of current research literature, summarized research... Read More about Vestibulotoxicity associated with platinum-based chemotherapy in survivors of cancer: a scoping review.

Betahistine for tinnitus (Protocol) (2018)
Journal Article
Hall, D. A., Wegner, . I., Smit, A. L., McFerran, D., & Stegeman, I. (2018). Betahistine for tinnitus (Protocol). Cochrane Database of Systematic Reviews, 2018(8), Article CD013093. https://doi.org/10.1002/14651858.CD013093

Background: Tinnitus describes 'ringing', 'whooshing' or 'hissing' sounds that are heard in the absence of any corresponding external sound. Between 5% and 43% of people experience this symptom and for some it has a significant negative impact on the... Read More about Betahistine for tinnitus (Protocol).

Sound therapy (using amplification devices and/or sound generators) for tinnitus in adults (Protocol) (2018)
Journal Article
Sereda, M., Xia, J., El Refaie, A., Hall, D. A., & Hoare, D. (2018). Sound therapy (using amplification devices and/or sound generators) for tinnitus in adults (Protocol). Cochrane Database of Systematic Reviews, 2018(8), Article CD013094. https://doi.org/10.1002/14651858.CD013094

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of sound therapy (using amplification devices and/or sound generators) for tinnitus in adults.

A narrative synthesis of research evidence for tinnitus-related complaints as reported by patients and their significant others (2018)
Journal Article
Hall, D. A., Fackrell, K. L., Li, A. B., Thavayogan, R., Smith, S., Kennedy, V., …Haider, H. (2018). A narrative synthesis of research evidence for tinnitus-related complaints as reported by patients and their significant others. Health and Quality of Life Outcomes, 16, Article 61. https://doi.org/10.1186/s12955-018-0888-9

Background: There are a large number of assessment tools for tinnitus, with little consensus on what it is important to measure and no preference for a minimum reporting standard. The item content of tinnitus assessment tools should seek to capture r... Read More about A narrative synthesis of research evidence for tinnitus-related complaints as reported by patients and their significant others.

The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study (Preprint) (2018)
Other
Dewey, R. S., Hall, D. A., Guest, H., Prendergast, G., Plack, C. J., & Francis, S. T. (2018). The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study (Preprint)

Background: Rodent studies indicate that noise exposure can cause permanent damage to synapses between inner hair cells and high-threshold auditory nerve fibers, without permanently altering threshold sensitivity. These demonstrations of what is c... Read More about The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study (Preprint).

The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study (2018)
Journal Article
Dewey, R. S., Hall, D. A., Guest, H., Prendergast, G., Plack, C. J., & Francis, S. T. (2018). The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study. JMIR Research Protocols, 7(3), Article e79. https://doi.org/10.2196/resprot.9095

Background: Rodent studies indicate that noise exposure can cause permanent damage to synapses between inner hair cells and high-threshold auditory nerve fibers, without permanently altering threshold sensitivity. These demonstrations of what is comm... Read More about The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study.

Defining and evaluating novel procedures for involving patients in Core Outcome Set research: creating a meaningful long list of candidate outcome domains (2018)
Journal Article
Smith, H., Horobin, A. J., Fackrell, K., Colley, V., Thacker, B., & Hall, D. A. (2018). Defining and evaluating novel procedures for involving patients in Core Outcome Set research: creating a meaningful long list of candidate outcome domains. Research Involvement and Engagement, 4(8), https://doi.org/10.1186/s40900-018-0091-5

Background Tinnitus is a complex audiological condition affecting many different domains of everyday life. Clinical trials of tinnitus interventions measure and report those outcome domains inconsistently and this hinders direct comparison between s... Read More about Defining and evaluating novel procedures for involving patients in Core Outcome Set research: creating a meaningful long list of candidate outcome domains.

Interpreting the Tinnitus Questionnaire (German version):what individual differences are clinically important? (2018)
Journal Article
Hall, D. A., Mehta, R., & Argstatter, H. (2018). Interpreting the Tinnitus Questionnaire (German version):what individual differences are clinically important?. International Journal of Audiology, 57(7), 553-557. https://doi.org/10.1080/14992027.2018.1442591

Objective: Reporting of clinical significance is recommended because findings can be statistically significant without being relevant to patients. For aiding clinical interpretation of the Tinnitus Questionnaire (TQ), many investigators use a 5-point... Read More about Interpreting the Tinnitus Questionnaire (German version):what individual differences are clinically important?.

Recruiting ENT and audiology patients into pharmaceutical trials: evaluating the multi-center experience in the UK and USA (2018)
Journal Article
Sanchez, V. A., Hall, D. A., Millar, B., Escabi, C. D., Sharman, A., Watson, J., …Harris, P. (in press). Recruiting ENT and audiology patients into pharmaceutical trials: evaluating the multi-center experience in the UK and USA. International Journal of Audiology, https://doi.org/10.1080/14992027.2018.1425002

Objective: Recruiting into clinical trials on time and on target is a major challenge, and yet often goes unreported. This study evaluated the adjustment to procedures, recruitment, and screening methods in two multi-center pharmaceutical randomized... Read More about Recruiting ENT and audiology patients into pharmaceutical trials: evaluating the multi-center experience in the UK and USA.

Diagnostic Criteria for Somatosensory Tinnitus: A Delphi Process and Face-to-Face Meeting to Establish Consensus (2018)
Journal Article
Michiels, S., Sanchez, T. G., Oron, Y., Gilles, A., Haider, H. F., Erlandsson, S., …Hall, D. A. (2018). Diagnostic Criteria for Somatosensory Tinnitus: A Delphi Process and Face-to-Face Meeting to Establish Consensus. Trends in Hearing, 22, 1-10. https://doi.org/10.1177/2331216518796403

Since somatic or somatosensory tinnitus (ST) was first described as a subtype of subjective tinnitus, where altered somatosensory afference from the cervical spine or temporomandibular area causes or changes a patient’s tinnitus perception, several s... Read More about Diagnostic Criteria for Somatosensory Tinnitus: A Delphi Process and Face-to-Face Meeting to Establish Consensus.