All Outputs (2)

The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain (2016)
Journal Article
Hulse, R. P., Drake, R. A., Bates, D. O., & Donaldson, L. F. (in press). The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain. Neurobiology of Disease, 96, https://doi.org/10.1016/j.nbd.2016.09.009

Neuropathic pain results from neuroplasticity in nociceptive neuronal networks. Here we demonstrate that control of alternative pre-mRNA splicing, through the splice factor serine-arginine splice factor 1 (SRSF1), is integral to the processing of noc... Read More about The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain.

Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt the vascular maturation in infantile haemangioma (2016)
Journal Article
Ye, X., Abou-Rayyah, Y., Bischoff, J., Ritchie, A., Sebire, N. J., Watts, P., …Bates, D. O. (in press). Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt the vascular maturation in infantile haemangioma. Journal of Pathology, 239(2), https://doi.org/10.1002/path.4715

Infantile haemangioma (IH), the most common neoplasm in infants, is a slowly resolving vascular tumour. Vascular endothelial growth factor A (VEGF-A), which consists of both the pro- and anti-angiogenic variants, contributes to the pathogenesis of IH... Read More about Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt the vascular maturation in infantile haemangioma.