Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo

Defang, Gabriel; Luke, Thomas; Wu, Hua; Zhao, Jincun; Channappanavar, Rudragouda; Coleman, Christopher M.; Jiao, Jin An; Matsushita, Hiroaki; Liu, Ye; Postnikova, Elena N.; Ork, Britini L.; Glenn, Gregory; Flyer, David; Raviprakash, Kanakatte; Kochel, Tadeusz; Smith, Gale; Hensley, Lisa E.; Olinger, Gene G.; Kuhn, Jens H.; Holbrook, Michael R.; Johnson, Reed F.; Wang, Jonathan; Perlman, Stanley; Sullivan, Eddie; Nie, Wensheng; Frieman, Matthew B.

doi:10.1126/scitranslmed.aaf1061

All Outputs (3)

CD8 + T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome (2016)
Journal Article
Coleman, C. M., Sisk, J. M., Halasz, G., Zhong, J., Beck, S. E., Matthews, K. L., …Frieman, M. B. (2017). CD8 + T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome. Journal of Virology, 91(1), https://doi.org/10.1128/jvi.01825-16

© 2016 American Society for Microbiology. Middle East respiratory syndrome coronavirus (MERS-CoV) is an important emerging pathogen that was first described in 2012. While the cell surface receptor for MERS-CoV has been identified as dipeptidyl pepti... Read More about CD8 + T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome.

Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion (2016)
Journal Article
Coleman, C. M., Sisk, J. M., Mingo, R. M., Nelson, E. A., White, J. M., & Frieman, M. B. (2016). Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion. Journal of Virology, 90(19), 8924-8933. https://doi.org/10.1128/jvi.01429-16

© 2016, American Society for Microbiology. All Rights Reserved. The highly pathogenic severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) cause significant morbidity and morality. There... Read More about Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion.

Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo (2016)
Journal Article
Defang, G., Luke, T., Wu, H., Zhao, J., Channappanavar, R., Coleman, C. M., …Frieman, M. B. (2016). Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Science Translational Medicine, 8(326), 326ra21-326ra21. https://doi.org/10.1126/scitranslmed.aaf1061

Copyright 2016 by the American Association for the Advancement of Science; all rights reserved. As of 13 November 2015, 1618 laboratory-confirmed human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, including 579 deaths,... Read More about Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo.