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Activation induced changes in GABA: functional MRS at 7 T with MEGA-sLASER (2017)
Journal Article
Chen, C., Sigurdsson, H. P., Pépés, S. E., Auer, D. P., Morris, P. G., Morgan, P. S., …Jackson, S. R. (2017). Activation induced changes in GABA: functional MRS at 7 T with MEGA-sLASER. NeuroImage, 156, doi:10.1016/j.neuroimage.2017.05.044. ISSN 1053-8119

Functional magnetic resonance spectroscopy (fMRS) has been used to assess the dynamic metabolic responses of the brain to a physiological stimulus non-invasively. However, only limited information on the dynamic functional response of γ-aminobutyric... Read More

The role of anti-aquaporin 4 antibody in the conversion of acute brainstem syndrome to neuromyelitis optica (2016)
Journal Article
Cheng, C., Jiang, Y., Lu, X., Gu, F., Kang, Z., Dai, Y., …Hu, X. (in press). The role of anti-aquaporin 4 antibody in the conversion of acute brainstem syndrome to neuromyelitis optica. BMC Neurology, 16(1), doi:10.1186/s12883-016-0721-1. ISSN 1471-2377

Background: Acute brainstem syndrome (ABS) may herald multiple sclerosis (MS), neuromyelitis optica (NMO), or occur as an isolated syndrome. The aquaporin 4 (AQP4)-specific serum autoantibody, NMO-IgG, is a biomarker for NMO. However, the role of ant... Read More

The properties of HPMC: PEO extended release hydrophilic matrices and their response to ionic environments (2016)
Journal Article
Hu, A., Chen, C., Mantle, M. D., Wolf, B., Gladden, L. F., Rajabi-Siahboomi, A., …Melia, C. D. (2017). The properties of HPMC: PEO extended release hydrophilic matrices and their response to ionic environments. Pharmaceutical Research, 34(5), doi:10.1007/s11095-016-2031-0. ISSN 0724-8741

Purpose Investigate the extended release behaviour of compacts containing mixtures of hydrophilic HPMC and PEO in hydrating media of differing ionic strengths. Methods The extended release behaviour of various HPMC:PEO compacts was investigate... Read More

Combining classical and molecular approaches elaborates on the complexity of mechanisms underpinning anterior regeneration (2011)
Journal Article
Evans, D. J., Owlarn, S., Romero, B. T., Chen, C., & Aboobaker, A. A. (2011). Combining classical and molecular approaches elaborates on the complexity of mechanisms underpinning anterior regeneration. PLoS ONE, 6(11), doi:10.1371/journal.pone.0027927. ISSN 1932-6203

The current model of planarian anterior regeneration evokes the establishment of low levels of Wnt signalling at anterior wounds, promoting anterior polarity and subsequent elaboration of anterior fate through the action of the TALE class homeodomain... Read More