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All Outputs (6)

Refining Ovarian Cancer Test accuracy Scores (ROCkeTS): protocol for a prospective longitudinal test accuracy study to validate new risk scores in women with symptoms of suspected ovarian cancer (2016)
Journal Article
Sundar, S., Rick, C., Dowling, F., Au, P., Snell, K., Rai, N., …Deeks, J. (2016). Refining Ovarian Cancer Test accuracy Scores (ROCkeTS): protocol for a prospective longitudinal test accuracy study to validate new risk scores in women with symptoms of suspected ovarian cancer. BMJ Open, 6(8), Article e010333. https://doi.org/10.1136/bmjopen-2015-010333

© 2016 Published by the BMJ Publishing Group Limited. Ovarian cancer (OC) is associated with non-specific symptoms such as bloating, making accurate diagnosis challenging: only 1 in 3 women with OC presents through primary care referral. National Ins... Read More about Refining Ovarian Cancer Test accuracy Scores (ROCkeTS): protocol for a prospective longitudinal test accuracy study to validate new risk scores in women with symptoms of suspected ovarian cancer.

Clinical effectiveness and cost-effectiveness of physiotherapy and occupational therapy versus no therapy in mild to moderate Parkinson’s disease: a large pragmatic randomised controlled trial (PD REHAB) (2016)
Journal Article
Clarke, C. E., Patel, S., Ives, N., Rick, C. E., Woolley, R., Wheatley, K., …Sackley, C. M. (2016). Clinical effectiveness and cost-effectiveness of physiotherapy and occupational therapy versus no therapy in mild to moderate Parkinson’s disease: a large pragmatic randomised controlled trial (PD REHAB). Health Technology Assessment, 20(63), https://doi.org/10.3310/hta20630

Background Cochrane reviews of physiotherapy (PT) and occupational therapy (OT) for Parkinson’s disease found insufficient evidence of effectiveness, but previous trials were methodologically flawed with small sample size and short-term follow-up.... Read More about Clinical effectiveness and cost-effectiveness of physiotherapy and occupational therapy versus no therapy in mild to moderate Parkinson’s disease: a large pragmatic randomised controlled trial (PD REHAB).

Patients’ experiences of deep brain stimulation for Parkinson's disease: a qualitative systematic review and synthesis (2016)
Journal Article
Mathers, J., Rick, C., Jenkinson, C., Garside, R., Pall, H., Mitchell, R., …Jones, L. L. (2016). Patients’ experiences of deep brain stimulation for Parkinson's disease: a qualitative systematic review and synthesis. BMJ Open, 6(6), 1-10. https://doi.org/10.1136/bmjopen-2016-011525

Objective: To review and synthesise qualitative research studies that have explored patients’ experience of deep brain stimulation (DBS) in advanced Parkinson's disease (PD). Design: Systematic review and meta-synthesis of 7 original papers, using... Read More about Patients’ experiences of deep brain stimulation for Parkinson's disease: a qualitative systematic review and synthesis.

Cost‐utility analysis of deep brain stimulation surgery plus best medical therapy versus best medical therapy in patients with Parkinson's: Economic evaluation alongside the PD SURG trial (2016)
Journal Article
McIntosh, E., Gray, A., Daniels, J., Gill, S., Ives, N., Jenkinson, C., …on behalf of The PD SURG Collaborators Group. (2016). Cost‐utility analysis of deep brain stimulation surgery plus best medical therapy versus best medical therapy in patients with Parkinson's: Economic evaluation alongside the PD SURG trial. Movement Disorders, 31(8), 1173-1182. https://doi.org/10.1002/mds.26423

Introduction Williams and colleagues reported that DBS surgery for patients with advanced PD improves motor function and quality of life compared to best medical therapy alone at 1 year, but with surgery‐related side effects in a minority. This ar... Read More about Cost‐utility analysis of deep brain stimulation surgery plus best medical therapy versus best medical therapy in patients with Parkinson's: Economic evaluation alongside the PD SURG trial.

Physiotherapy and occupational therapy vs no therapy in mild to moderate Parkinson disease: a randomized clinical trial (2016)
Journal Article
Clarke, C. E., Patel, S., Ives, N., Dowling, F., Rick, C. E., Woolley, R., …Sackley, C. M. (in press). Physiotherapy and occupational therapy vs no therapy in mild to moderate Parkinson disease: a randomized clinical trial. JAMA Neurology, 73(3), https://doi.org/10.1001/jamaneurol.2015.4452

IMPORTANCE It is unclear whether physiotherapy and occupational therapy are clinically effective and cost-effective in Parkinson disease (PD). OBJECTIVE To perform a large pragmatic randomized clinical trial to evaluate the clinical effectiveness of... Read More about Physiotherapy and occupational therapy vs no therapy in mild to moderate Parkinson disease: a randomized clinical trial.

A systematic review of interventions to reduce hospitalisation in Parkinson's disease (2016)
Journal Article
Muzerengi, S., Herd, C., Rick, C., & Clarke, C. (2016). A systematic review of interventions to reduce hospitalisation in Parkinson's disease. Parkinsonism and Related Disorders, 24, 3-7. https://doi.org/10.1016/j.parkreldis.2016.01.011

The neurodegenerative process in Parkinson's disease (PD) results in a relentless progression of motor and non-motor symptoms. Affected individuals are frequently hospitalised for complications of the disease including falls, fractures, infections, a... Read More about A systematic review of interventions to reduce hospitalisation in Parkinson's disease.