All Outputs (3)

Urine tests for Down's syndrome screening (2015)
Journal Article
Alldred, S. K., Guo, B., Takwoingi, Y., Pennant, M., Wisniewski, S., Deeks, J. J., …Alldred, S. K. (2015). Urine tests for Down's syndrome screening. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD011984

Background

Down's syndrome occurs when a person has three copies of chromosome 21, or the specific area of chromosome 21 implicated in causing Down's syndrome, rather than two. It is the commonest congenital cause of mental disability and also lea... Read More about Urine tests for Down's syndrome screening.

Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data (2015)
Journal Article
Takwoingi, Y., Guo, B., Riley, R. D., & Deeks, J. J. (2015). Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data. Statistical Methods in Medical Research, https://doi.org/10.1177/0962280215592269

Hierarchical models such as the bivariate and hierarchical summary receiver operating characteristic (HSROC) models are recommended for meta-analysis of test accuracy studies. These models are challenging to fit when there are few studies and/or spar... Read More about Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data.

First trimester serum tests for Down's syndrome screening (2015)
Journal Article
Alldred, S. K., Takwoingi, Y., Guo, B., Pennant, M., Deeks, J. J., Neilson, J. P., & Alfirevic, Z. (2015). First trimester serum tests for Down's syndrome screening. Cochrane Database of Systematic Reviews, 11, Article CD011975. https://doi.org/10.1002/14651858.CD011975

Background

Down's syndrome occurs when a person has three, rather than two copies of chromosome 21; or the specific area of chromosome 21 implicated in causing Down's syndrome. It is the commonest congenital cause of mental disability and also lea... Read More about First trimester serum tests for Down's syndrome screening.