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All Outputs (41)

A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study (2022)
Journal Article
Lee, A. R., McDermott, O., Guo, B., Roe, J., & Orrell, M. (2022). A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study. JMIR Research Protocols, 11(7), Article e33881. https://doi.org/10.2196/33881

Background: With the rapid increase in the prevalence of dementia in the United Kingdom and beyond, the emotional, social, and economic burden on individuals, families, and health care services continues to rise. Currently, interventions that enable... Read More about A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study.

Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals (2022)
Journal Article
Andrews, J. A., Craven, M. P., Lang, A. R., Guo, B., Morriss, R., Hollis, C., & RADAR-CNS Consortium. (2022). Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals. BMC Medical Informatics and Decision Making, 22(1), Article 125. https://doi.org/10.1186/s12911-022-01856-z

BACKGROUND: Epilepsy, multiple sclerosis(MS) and depression are long term, central nervous system disorders which have a significant impact on everyday life. Evaluating symptoms of these conditions is problematic and typically involves repeated visit... Read More about Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals.

A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial) (2022)
Journal Article
Patel, S., Boutry, C., Patel, P., Craven, M. P., Guo, B., Zafar, A., …Morriss, R. (2022). A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial). Trials, 23(1), Article 250. https://doi.org/10.1186/s13063-022-06192-1

Background: Major depression is the second leading cause of years lost to disability worldwide and is a leading contributor to suicide. However, first-line antidepressants are only fully effective for 33%, and only 40% of those offered psychological... Read More about A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial).

Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey (2022)
Journal Article
Roe, J., Cresswell, A., Mittal, S., Al-Uzri, M., Tanner, J., Moore, M., …Morriss, R. (2022). Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey. Journal of Mental Health, 31(5), 724-731. https://doi.org/10.1080/09638237.2021.2022614

Clinical guidelines for mental health disorders produced by the National Institute of Care Excellence (NICE) emphasise a recovery-based approach clinical care with collaborative decision-making. The aim of the study was to explore service user experi... Read More about Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey.

Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit (2022)
Journal Article
Coleston-Shields, D. M., Challis, D., Worden, A., Broome, E., Dening, T., Guo, B., …Orrell, M. (2022). Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit. Trials, 23, Article 54. https://doi.org/10.1186/s13063-021-05995-y

Background: Improving care at home for people with dementia is a core policy goal in the dementia strategies of many European countries. A challenge to effective home support is the occurrence of crises in the care of people with dementia which arise... Read More about Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit.

The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey (2021)
Journal Article
Andrews, J. A., Craven, M. P., Lang, A. R., Guo, B., Morriss, R., Hollis, C., & The RADAR-CNS Consortium. (2021). The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey. BMC Medical Informatics and Decision Making, 21, Article 282. https://doi.org/10.1186/s12911-021-01640-5

Background: A variety of smartphone apps and wearables are available both to help patients monitor their health and to support health care professionals (HCPs) in providing clinical care. As part of the RADAR-CNS consortium, we have conducted researc... Read More about The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey.

Correction: A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial (2021)
Journal Article
Morriss, R., Kaylor-Hughes, C., Rawsthorne, M., Coulson, N., Simpson, S., Guo, B., …Williams, L. (2021). Correction: A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial. Journal of Medical Internet Research, 23(7), Article e31543. https://doi.org/10.2196/31543

[This corrects the article DOI: 10.2196/23487.].

The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time (2021)
Journal Article
Guo, B., Li, L., Crawford, M. J., & Morriss, R. (2021). The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time. International Journal of Methods in Psychiatric Research, 30(3), Article e1874. https://doi.org/10.1002/mpr.1874

Objectives There is a lack of independent longitudinal evidence on the factor structure and validity of the Zanarini Rating Scale for Borderline Personality Disorder (ZAN?BPD). This study aimed to investigate the dimensionality of ZAN?BPD and its... Read More about The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time.

A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial (2021)
Journal Article
Rawsthorne, M., Tata, L., Williams, L., Morriss, R., Guo, B., Simpson, S., …Moran, P. (2021). A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial. JMIR, 23(4), Article e23487. https://doi.org/10.2196/23487

Background: Effective help for depression and anxiety reaches a small proportion of people who might benefit from it. The scale of the problem suggests the need for effective, safe web-based public health services delivered directly to the public. On... Read More about A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial.

Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., …Groom, M. J. (2021). Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 68. https://doi.org/10.1186/s40814-021-00788-1

Background Medication for attention deficit hyperactivity disorder (ADHD) should be closely monitored to ensure optimisation. There is growing interest in using computerised assessments of ADHD symptoms to support medication monitoring. The aim of t... Read More about Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial.

The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial (2021)
Journal Article
Browning, M., Bilderbeck, A. C., Dias, R., Dourish, C. T., Kingslake, J., Deckert, J., …Dawson, G. R. (2021). The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial. Neuropsychopharmacology, 46, 1307–1314. https://doi.org/10.1038/s41386-021-00981-z

Depressed patients often do not respond to the first antidepressant prescribed, resulting in sequential trials of different medications. Personalised medicine offers a means of reducing this delay, however the clinical effectiveness of personalised a... Read More about The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial.

Pilot Randomised Evaluation of Singing in Dementia (PRESIDE): protocol for a two-arm, parallel group randomised controlled feasibility study with waiting-list control (2021)
Journal Article
Dowson, B., Schneider, J., Guo, B., Bath, P. M., Mcdermott, O., Haywood, L. J., & Orrell, M. (2021). Pilot Randomised Evaluation of Singing in Dementia (PRESIDE): protocol for a two-arm, parallel group randomised controlled feasibility study with waiting-list control. Pilot and Feasibility Studies, 7, Article 15. https://doi.org/10.1186/s40814-020-00759-y

Background As the number of people living with dementia grows, so does the need to provide them with adequate psychosocial support. Many people with dementia live at home with family carers, who also require social and emotional support to cope wi... Read More about Pilot Randomised Evaluation of Singing in Dementia (PRESIDE): protocol for a two-arm, parallel group randomised controlled feasibility study with waiting-list control.

Outcomes of a public health campaign and automated randomised controlled trial of a direct to public peer support programme (Big White Wall) versus web-based information to aid self-management of depression and anxiety (The REBOOT study) (2020)
Working Paper
Morriss, R., Kaylor-Hughes, C., Rawsthorne, M., Coulson, N., Simpson, S., Guo, B., …Williams, L. Outcomes of a public health campaign and automated randomised controlled trial of a direct to public peer support programme (Big White Wall) versus web-based information to aid self-management of depression and anxiety (The REBOOT study)

Background: Effective help for depression and anxiety only reaches a small proportion of those who might benefit from it. The scale of the problem suggests a role for effective, safe public health online services delivered directly to the public. On... Read More about Outcomes of a public health campaign and automated randomised controlled trial of a direct to public peer support programme (Big White Wall) versus web-based information to aid self-management of depression and anxiety (The REBOOT study).

The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome (2020)
Journal Article
Nixon, N., Guo, B., Garland, A., Kaylor-Hughes, C., Nixon, E., & Morriss, R. (2020). The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome. PLoS ONE, 15(10), Article e0241370. https://doi.org/10.1371/journal.pone.0241370

Background: The 17-item Hamilton Depression Rating Scale (HDRS17) is used world-wide as an observer-rated measure of depression in randomised controlled trials (RCTs) despite continued uncertainty regarding its factor structure. This study investiga... Read More about The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome.

Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study (2020)
Journal Article
Aldridge, Z., Patel, S., Guo, B., Nixon, E., Bouman, W. P., Witcomb, G. L., & Arcelus, J. (2021). Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study. Andrology, 9(6), 1808-1816. https://doi.org/10.1111/andr.12884

Background Cross-sectional studies show that transgender people are more likely than cisgender people to experience depression and anxiety before Gender Affirming Hormone Treatment (GAHT). However, the effect of GAHT on mental health in transgender... Read More about Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study.

Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study (2020)
Journal Article
Aldridge, Z., Patel, S., Guo, B., Nixon, E., Pierre Bouman, W., Witcomb, G. L., & Arcelus, J. (2021). Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study. Andrology, 9(6), 1808-1816. https://doi.org/10.1111/andr.12884

Background Cross?sectional studies show that transgender people are more likely than cisgender people to experience depression and anxiety before Gender Affirming Hormone Treatment (GAHT). However, the effect of GAHT on mental health in transgende... Read More about Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study.

SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus (2019)
Conference Proceeding
Blake, H., Knox, E., Randell, T., Leighton, P., Guo, B., Greening, J., …Glazebrook, C. (2019). SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus. In 5th International Clinical Trials Methodology Conference (ICTMC 2019) Book of Abstracts

Introduction: Physical activity is important for children with type 1 diabetes mellitus (T1DM) but it is unclear whether interventions delivered online are feasible, acceptable to patients and efficacious. The aim was to assess the feasibility and ac... Read More about SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus.

The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms (2019)
Journal Article
Hall, C. L., Guo, B., Valentine, A. Z., Groom, M. J., Daley, D., Sayal, K., & Hollis, C. (2019). The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms. PLoS ONE, 14(6), Article e0218518. https://doi.org/10.1371/journal.pone.0218518

Background: The Strengths and Difficulties Questionnaire (SDQ) is widely used to assess child and adolescent mental health problems. However, the factor structure of the SDQ is subject to debate and there is limited evidence investigating measurement... Read More about The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms.

The Validity of the SNAP-IV in Children Displaying ADHD Symptoms (2019)
Journal Article
Hall, C. L., Guo, B., Valentine, A. Z., Groom, M. J., Daley, D., Sayal, K., & Hollis, C. (2020). The Validity of the SNAP-IV in Children Displaying ADHD Symptoms. Assessment, 27(6), 1258-1271. https://doi.org/10.1177/1073191119842255

The Swanson, Nolan, and Pelham Rating Scale (SNAP-IV) is a widely used scale that measures the core symptoms of attention deficit hyperactivity disorder (ADHD). However, there are contradictory findings regarding factor structure. Factor structure an... Read More about The Validity of the SNAP-IV in Children Displaying ADHD Symptoms.